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- W2750979344 endingPage "160" @default.
- W2750979344 startingPage "152" @default.
- W2750979344 abstract "Bevacizumab is a vascular endothelial growth factor-A-specific angiogenesis inhibitor indicated as an adjunct to chemotherapy for the treatment of several types of cancer. Hypertension is commonly observed during bevacizumab treatment, and high-grade toxicity can limit therapy and lead to other cardiovascular complications. The factors that contribute to interindividual variability in blood pressure response to bevacizumab treatment are not well understood. In this review, we outline research efforts to understand the mechanisms and pathophysiology of hypertension resulting from bevacizumab treatment. Moreover, we highlight current knowledge of the pharmacogenetics of bevacizumab-induced hypertension, which may be used to develop strategies to prevent or minimize this toxicity." @default.
- W2750979344 created "2017-09-15" @default.
- W2750979344 creator A5000349543 @default.
- W2750979344 creator A5055451852 @default.
- W2750979344 date "2018-02-01" @default.
- W2750979344 modified "2023-10-14" @default.
- W2750979344 title "Bevacizumab-induced hypertension: Clinical presentation and molecular understanding" @default.
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