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- W2750996938 abstract "A-33-year-old man with bronchial asthma received budesonide and formoterol fumarate powder for inhalation one suction twice daily (one suck containing budesonide 160 μg and formoterol 4.5 μg). After 6 days of treatment, he developed the symptoms of fever (temperature of 38.2 ℃), headache, nasal obstruction, runny nose and sneeze. He took paracetamol, pseudoephedrine hydrochloride, dextrome-thorphan hydrobromide and chlorphenamine maleate one tablet thrice daily by himself. Two days later, the body temperature returned to normal and the headache was relieved. The follow day, paracetamol, pseudoephedrine hydrochloride, dextromethorphan hydrobromide and chlorphenamine maleate was stopped, the nasal obstruction and runny nose slightly better but continuous. The budesonide and formoterol fumarate powder for inhalation was discontinued after one month because of the patient absent re-visiting in time. The symptoms of nasal obstruction and runny nose were relieved in the second day and disappear in the third day. The patient was using the drug again at intervals of 3 days, the flu-like symptoms recurred in 30 minutes and the body temperature reached 38.8 ℃. Drug-induced flu-like syndrome was considered. Budesonide and formoterol fumarate powder for inhalation was stopped and changed to salmeterol xinafoate and fluticasone propionate powder for inhalation. Loratadine and acetaminophen were given. The flu-like symptoms did not recur during four weeks of follow-up.Key words: Budesonide; Formoterol fumarate; Influenza, human; Signs and symptoms" @default.
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- W2750996938 date "2016-10-28" @default.
- W2750996938 modified "2023-09-28" @default.
- W2750996938 title "Drug-induced flu-like syndrome caused by budesonide and formoterol fumarate powder for inhalation" @default.
- W2750996938 doi "https://doi.org/10.3760/cma.j.issn.1008-5734.2016.05.012" @default.
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