FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2751108855> ?p ?o ?g. }

• W2751108855 endingPage "263" @default.
• W2751108855 startingPage "255" @default.
• W2751108855 abstract "Environmental enrichment (EE) has been associated with many effects on the behavior of laboratory animals.  The term EE is rather vague, often referring to a variety of item combinations as if what is added to  the cage has no significance. EE is indeed housing refinement, and therefore more exact terms should be  used to clarify the situation. This study was designed to assess whether access to a nest box (NB) could  modify behavior of BALB/c mice in the plus-maze test. Two series of experiments were done with an aspen  NB (11 x 11 x 7 cm, wall thickness 1.5 cm, two round holes (d = 3 cm) at opposite sides. Control mice had  no added item in the cage. The plus-maze consisted of two open (8 x 17 cm) and two closed arms (8 x 17  x 30 cm) connected by a central platform (8 x 8 cm). Mice were placed on the central platform facing an  open arm. During five minutes, the numbers of entries made onto the open and into the closed arms were  recorded. From this data, the percentages of entries made onto the open arms, and the percentage of time  spent on the open arms, were calculated. Furthermore, the number of fecal boli left by the mice in the plusmaze,  as a stress indicator, were counted. In the first series of experiments NB was present for one, two  and three weeks but no drugs were administered. NB provided for one or two weeks had no effect on the  behavior of mice. However, exposure to NB for three weeks did decrease the locomotor activity of mice in  the plus-maze test, as reflected in the decline in the total number of entries made in the test. The presence  of NB for one or two weeks resulted in more (p = 0.001) fecal boli voided when compared to the no NB  or NB for three weeks groups.  In the second series of experiments we used NB for 10 days and the selective neuronal nitric oxide synthase  (nNOS) inhibitor 1-(2-trifluoromethylphenyl)-imidazole (TRIM) as a pharmacological tool (at doses  of 25.0, 50.0 and 100.0 mg/kg, i.p.). Depending on the dose, the administration of TRIM induced an anxiolytic  (50 mg/kg) or sedative effect (100 mg/kg) as seen in the increase in the percentage of entries made  onto the open arms or a decrease in the total number of entries, respectively. NB for 10 days had no effect  on the behavior of mice or on the effect of TRIM. In conclusion, NB does not appear to interfere with the anxiolytic effect of TRIM in the plus-maze test but  prolonged exposure to NB does reduce the locomotor  activity of mice.Â" @default.
• W2751108855 created "2017-09-15" @default.
• W2751108855 creator A5013174865 @default.
• W2751108855 creator A5013616853 @default.
• W2751108855 creator A5034093604 @default.
• W2751108855 creator A5037820841 @default.
• W2751108855 creator A5044846625 @default.
• W2751108855 creator A5082664124 @default.
• W2751108855 date "2007-01-01" @default.
• W2751108855 modified "2023-09-23" @default.
• W2751108855 title "Prolonged Exposure of Mice to a Nest Box Reduces Locomotor Activity in the Plus-Maze Test" @default.
• W2751108855 cites W1491397924 @default.
• W2751108855 cites W2000672600 @default.
• W2751108855 cites W2027326698 @default.
• W2751108855 cites W2032058764 @default.
• W2751108855 cites W2119535782 @default.
• W2751108855 cites W2137482757 @default.
• W2751108855 cites W2145597472 @default.
• W2751108855 cites W2147434439 @default.
• W2751108855 cites W2410450878 @default.
• W2751108855 cites W2432644488 @default.
• W2751108855 cites W2397536154 @default.
• W2751108855 hasPublicationYear "2007" @default.
• W2751108855 type Work @default.
• W2751108855 sameAs 2751108855 @default.
• W2751108855 citedByCount "2" @default.
• W2751108855 countsByYear W27511088552012 @default.
• W2751108855 crossrefType "journal-article" @default.
• W2751108855 hasAuthorship W2751108855A5013174865 @default.
• W2751108855 hasAuthorship W2751108855A5013616853 @default.
• W2751108855 hasAuthorship W2751108855A5034093604 @default.
• W2751108855 hasAuthorship W2751108855A5037820841 @default.
• W2751108855 hasAuthorship W2751108855A5044846625 @default.
• W2751108855 hasAuthorship W2751108855A5082664124 @default.
• W2751108855 hasConcept C114614502 @default.
• W2751108855 hasConcept C118552586 @default.
• W2751108855 hasConcept C126322002 @default.
• W2751108855 hasConcept C140793950 @default.
• W2751108855 hasConcept C15744967 @default.
• W2751108855 hasConcept C160272327 @default.
• W2751108855 hasConcept C173586616 @default.
• W2751108855 hasConcept C2992926266 @default.
• W2751108855 hasConcept C33070731 @default.
• W2751108855 hasConcept C33923547 @default.
• W2751108855 hasConcept C53927964 @default.
• W2751108855 hasConcept C558461103 @default.
• W2751108855 hasConcept C71924100 @default.
• W2751108855 hasConcept C86803240 @default.
• W2751108855 hasConceptScore W2751108855C114614502 @default.
• W2751108855 hasConceptScore W2751108855C118552586 @default.
• W2751108855 hasConceptScore W2751108855C126322002 @default.
• W2751108855 hasConceptScore W2751108855C140793950 @default.
• W2751108855 hasConceptScore W2751108855C15744967 @default.
• W2751108855 hasConceptScore W2751108855C160272327 @default.
• W2751108855 hasConceptScore W2751108855C173586616 @default.
• W2751108855 hasConceptScore W2751108855C2992926266 @default.
• W2751108855 hasConceptScore W2751108855C33070731 @default.
• W2751108855 hasConceptScore W2751108855C33923547 @default.
• W2751108855 hasConceptScore W2751108855C53927964 @default.
• W2751108855 hasConceptScore W2751108855C558461103 @default.
• W2751108855 hasConceptScore W2751108855C71924100 @default.
• W2751108855 hasConceptScore W2751108855C86803240 @default.
• W2751108855 hasIssue "4" @default.
• W2751108855 hasOpenAccess W2751108855 @default.
• W2751108855 hasRelatedWork W1164385966 @default.
• W2751108855 hasRelatedWork W1968387526 @default.
• W2751108855 hasRelatedWork W201530117 @default.
• W2751108855 hasRelatedWork W2015933888 @default.
• W2751108855 hasRelatedWork W2027527730 @default.
• W2751108855 hasRelatedWork W2034872365 @default.
• W2751108855 hasRelatedWork W2035743528 @default.
• W2751108855 hasRelatedWork W2037364272 @default.
• W2751108855 hasRelatedWork W2069970074 @default.
• W2751108855 hasRelatedWork W2167298203 @default.
• W2751108855 hasRelatedWork W2181747285 @default.
• W2751108855 hasRelatedWork W2313879621 @default.
• W2751108855 hasRelatedWork W2317012847 @default.
• W2751108855 hasRelatedWork W2332080832 @default.
• W2751108855 hasRelatedWork W2379785912 @default.
• W2751108855 hasRelatedWork W2419613556 @default.
• W2751108855 hasRelatedWork W2605818295 @default.
• W2751108855 hasRelatedWork W2994317813 @default.
• W2751108855 hasRelatedWork W2186992890 @default.
• W2751108855 hasRelatedWork W2188427011 @default.
• W2751108855 hasVolume "34" @default.
• W2751108855 isParatext "false" @default.
• W2751108855 isRetracted "false" @default.
• W2751108855 magId "2751108855" @default.
• W2751108855 workType "article" @default.