FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2751114927> ?p ?o ?g. }

• W2751114927 abstract "Nowadays the multidrug-resistant (MDR) bacterial pathogens are a major concern of the medical science. Medicinal plants may be considered as new sources for producing antibacterial agents. The present study aimed to standardize an improved method for micropropagation and in vitro biomass production of Bacopa monnieri. Second aim is to evaluate the antimicrobial potency of in vitro cultured and ex vitro field grown micropropagated plants against different MDR clinical isolates of human urinary tract infecting (UTI) and respiratory tract infecting (RTI) pathogens. Micropropagation of B. monnieri were performed following standard tissue culture method. The role of 6-benzylaminopurine (BAP), kinetin and spermidine on multiple shoot induction were evaluated. Antimicrobial activity of ethanol, methanol and acetone extract of in vitro and ex vitro plants of B. monnieri were screened by agar cup method against five MDR-UTI bacteria, four MDR-RTI bacteria and three microbial type culture collection (MTCC) bacteria and two fungi. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were also determined. Synergistic effect of BAP and spermidine had improved shoot induction with a maximum of 123.8 shoot-buds per explant. Optimum micropropagation with 34.9 elongated shoots per explant was recorded in Murashige and Skoog medium containing 1.5 mg/L BAP and 2.0 mM spermidine. Methanolic extract of ex vitro plants showed maximum activity against MDR-UTI strain of Escherichia coli (sample-9) [ZI 18 ± 0.68 mm, MIC 2.5 μg/mL, MBC 5.0 μg/mL]. Acetone extract of ex vitro plant exhibited maximum inhibition against MDR-RTI strain of Klebsiella pneumoniae (sample-38) [ZI 14 ± 0.22 mm, MIC 5.0 μg/mL, MBC 7.5 μg/mL]. The extracts of B. monnieri were bactericidal rather than bacteriostatic against all UTI and RTI bacteria tested. The present manuscript demonstrated an efficient in vitro method for large scale biomass production of B. monnieri. Furthermore, the methanolic extract of B. monnieri have potential antimicrobial activity against clinical isolates of MDR-UTI and MDR-RTI bacterial strains. Hence this plant may further use to treat these infectious diseases. The comparative results show ex vitro grown plants have slightly better antimicrobial activities as compared to the in vitro plants." @default.
• W2751114927 created "2017-09-15" @default.
• W2751114927 creator A5015483936 @default.
• W2751114927 creator A5017176151 @default.
• W2751114927 creator A5026768626 @default.
• W2751114927 creator A5037845988 @default.
• W2751114927 creator A5038248030 @default.
• W2751114927 creator A5057173415 @default.
• W2751114927 date "2017-09-27" @default.
• W2751114927 modified "2023-10-04" @default.
• W2751114927 title "Improved micropropagation of Bacopa monnieri (L.) Wettst. (Plantaginaceae) and antimicrobial activity of in vitro and ex vitro raised plants against multidrug-resistant clinical isolates of urinary tract infecting (UTI) and respiratory tract infecting (RTI) bacteria" @default.
• W2751114927 cites W1528940404 @default.
• W2751114927 cites W1897230168 @default.
• W2751114927 cites W1960613750 @default.
• W2751114927 cites W1979973356 @default.
• W2751114927 cites W1980436481 @default.
• W2751114927 cites W1984183838 @default.
• W2751114927 cites W1988628462 @default.
• W2751114927 cites W1991650405 @default.
• W2751114927 cites W1996286992 @default.
• W2751114927 cites W2001910744 @default.
• W2751114927 cites W2003900175 @default.
• W2751114927 cites W2005621581 @default.
• W2751114927 cites W2024556021 @default.
• W2751114927 cites W2038751208 @default.
• W2751114927 cites W2043465566 @default.
• W2751114927 cites W2044389340 @default.
• W2751114927 cites W2047151085 @default.
• W2751114927 cites W2049531291 @default.
• W2751114927 cites W2053626254 @default.
• W2751114927 cites W2068697138 @default.
• W2751114927 cites W2093512385 @default.
• W2751114927 cites W2132981204 @default.
• W2751114927 cites W2136319945 @default.
• W2751114927 cites W2158647404 @default.
• W2751114927 cites W2164760065 @default.
• W2751114927 cites W2185564569 @default.
• W2751114927 cites W2214538883 @default.
• W2751114927 cites W2304275425 @default.
• W2751114927 cites W2309704116 @default.
• W2751114927 cites W2315348758 @default.
• W2751114927 cites W2317321563 @default.
• W2751114927 cites W2337508576 @default.
• W2751114927 cites W2465454952 @default.
• W2751114927 cites W2474974041 @default.
• W2751114927 cites W4251715317 @default.
• W2751114927 doi "https://doi.org/10.1186/s40816-017-0055-6" @default.
• W2751114927 hasPublicationYear "2017" @default.
• W2751114927 type Work @default.
• W2751114927 sameAs 2751114927 @default.
• W2751114927 citedByCount "19" @default.
• W2751114927 countsByYear W27511149272018 @default.
• W2751114927 countsByYear W27511149272019 @default.
• W2751114927 countsByYear W27511149272020 @default.
• W2751114927 countsByYear W27511149272021 @default.
• W2751114927 countsByYear W27511149272022 @default.
• W2751114927 countsByYear W27511149272023 @default.
• W2751114927 crossrefType "journal-article" @default.
• W2751114927 hasAuthorship W2751114927A5015483936 @default.
• W2751114927 hasAuthorship W2751114927A5017176151 @default.
• W2751114927 hasAuthorship W2751114927A5026768626 @default.
• W2751114927 hasAuthorship W2751114927A5037845988 @default.
• W2751114927 hasAuthorship W2751114927A5038248030 @default.
• W2751114927 hasAuthorship W2751114927A5057173415 @default.
• W2751114927 hasBestOaLocation W27511149271 @default.
• W2751114927 hasConcept C157890192 @default.
• W2751114927 hasConcept C202751555 @default.
• W2751114927 hasConcept C21410773 @default.
• W2751114927 hasConcept C2780433948 @default.
• W2751114927 hasConcept C2780822416 @default.
• W2751114927 hasConcept C4937899 @default.
• W2751114927 hasConcept C55493867 @default.
• W2751114927 hasConcept C59822182 @default.
• W2751114927 hasConcept C86803240 @default.
• W2751114927 hasConcept C89423630 @default.
• W2751114927 hasConceptScore W2751114927C157890192 @default.
• W2751114927 hasConceptScore W2751114927C202751555 @default.
• W2751114927 hasConceptScore W2751114927C21410773 @default.
• W2751114927 hasConceptScore W2751114927C2780433948 @default.
• W2751114927 hasConceptScore W2751114927C2780822416 @default.
• W2751114927 hasConceptScore W2751114927C4937899 @default.
• W2751114927 hasConceptScore W2751114927C55493867 @default.
• W2751114927 hasConceptScore W2751114927C59822182 @default.
• W2751114927 hasConceptScore W2751114927C86803240 @default.
• W2751114927 hasConceptScore W2751114927C89423630 @default.
• W2751114927 hasIssue "1" @default.
• W2751114927 hasLocation W27511149271 @default.
• W2751114927 hasOpenAccess W2751114927 @default.
• W2751114927 hasPrimaryLocation W27511149271 @default.
• W2751114927 hasRelatedWork W1989950808 @default.
• W2751114927 hasRelatedWork W2048910667 @default.
• W2751114927 hasRelatedWork W2093512385 @default.
• W2751114927 hasRelatedWork W2182266173 @default.
• W2751114927 hasRelatedWork W2183724132 @default.
• W2751114927 hasRelatedWork W2938739276 @default.
• W2751114927 hasRelatedWork W3039219092 @default.
• W2751114927 hasRelatedWork W3041797579 @default.
• W2751114927 hasRelatedWork W2185322125 @default.
• W2751114927 hasRelatedWork W2187185605 @default.
• W2751114927 hasVolume "3" @default.

• next