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- W2751234803 abstract "// Jing Zhang 1, * , Linrui Cai 2, * , Yanlin Song 3, * , Baoyin Shan 1 , Min He 1 , Qingqing Ren 1 , Chaoyue Chen 1 , Zhiyong Liu 1 , Yunhui Zeng 1 and Jianguo Xu 1 1 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, PR China 2 National Drug Clinical Trial Institute of West China Second University Hospital, Sichuan University, Chengdu 610041, PR China 3 West China School of Medicine, West China Hospital, Sichuan University, Chengdu 610041, PR China * These authors have contributed equally to this work Correspondence to: Jianguo Xu, email: jianguo_1229@126.com Keywords: neutrophil lymphocyte ratio, intracerebral hemorrhage, prognosis, outcome Received: May 23, 2017 Accepted: July 30, 2017 Published: September 08, 2017 ABSTRACT The aim of this study was to evaluate the prognostic role of neutrophil lymphocyte ratio (NLR) in patients with spontaneous intracerebral hemorrhage (ICH). PubMed, EMBASE, Web of Knowledge, Cochrane Library and China National Knowledge Infrastructure were searched for potentially relevant literature. The study and patient characteristics were extracted. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to estimate the prognostic role of NLR in patients with ICH. Poor functional outcome was defined as modified Rankin Scale≥3. Four studies with 1,720 patients were included. The pooled OR of higher NLR for poor functional outcome at 3 months was 2.74 (95% CI, 1.33-5.65). The pooled OR of higher NLR for death at 3 months was 1.58 (95% CI, 0.44-5.68). Subgroup analysis and sensitivity analysis were also performed. Publication bias was not present. In conclusion, for patients with ICH, higher NLR was associated with poorer functional outcome at 3 months, while higher NLR was not associated with higher risk of death at 3 months." @default.
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- W2751234803 date "2017-09-08" @default.
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- W2751234803 title "Prognostic role of neutrophil lymphocyte ratio in patients with spontaneous intracerebral hemorrhage" @default.
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- W2751234803 doi "https://doi.org/10.18632/oncotarget.20776" @default.
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