Matches in SemOpenAlex for { <https://semopenalex.org/work/W2751361130> ?p ?o ?g. }
- W2751361130 endingPage "810" @default.
- W2751361130 startingPage "801" @default.
- W2751361130 abstract "Review of literature.This review of literature investigates the application of mesenchymal stem cells (MSCs) in spinal fusion, highlights potential uses in the development of bone grafts, and discusses limitations based on both preclinical and clinical models.A review of literature was conducted looking at current studies using stem cells for augmentation of spinal fusion in both animal and human models.Eleven preclinical studies were found that used various animal models. Average fusion rates across studies were 59.8% for autograft and 73.7% for stem cell-based grafts. Outcomes included manual palpation and stressing of the fusion, radiography, micro-computed tomography (μCT), and histological analysis. Fifteen clinical studies, 7 prospective and 8 retrospective, were found. Fusion rates ranged from 60% to 100%, averaging 87.1% in experimental groups and 87.2% in autograft control groups.It appears that there is minimal clinical difference between commercially available stem cells and bone marrow aspirates indicating that MSCs may be a good choice in a patient with poor marrow quality. Overcoming morbidity and limitations of autograft for spinal fusion, remains a significant problem for spinal surgeons and further studies are needed to determine the efficacy of stem cells in augmenting spinal fusion." @default.
- W2751361130 created "2017-09-15" @default.
- W2751361130 creator A5035312942 @default.
- W2751361130 creator A5045395453 @default.
- W2751361130 creator A5053484529 @default.
- W2751361130 creator A5066181773 @default.
- W2751361130 date "2017-09-01" @default.
- W2751361130 modified "2023-10-01" @default.
- W2751361130 title "Stem Cells in Spinal Fusion" @default.
- W2751361130 cites W141499538 @default.
- W2751361130 cites W1566311357 @default.
- W2751361130 cites W1631413635 @default.
- W2751361130 cites W1965525642 @default.
- W2751361130 cites W1965700550 @default.
- W2751361130 cites W1970771505 @default.
- W2751361130 cites W1981264906 @default.
- W2751361130 cites W1984213135 @default.
- W2751361130 cites W1985202261 @default.
- W2751361130 cites W1988942062 @default.
- W2751361130 cites W1992132297 @default.
- W2751361130 cites W1992245406 @default.
- W2751361130 cites W1992274596 @default.
- W2751361130 cites W1995741855 @default.
- W2751361130 cites W2001788240 @default.
- W2751361130 cites W2007823854 @default.
- W2751361130 cites W2008454791 @default.
- W2751361130 cites W2009743923 @default.
- W2751361130 cites W2013957375 @default.
- W2751361130 cites W2025371271 @default.
- W2751361130 cites W2031196293 @default.
- W2751361130 cites W2032130665 @default.
- W2751361130 cites W2032458162 @default.
- W2751361130 cites W2032785541 @default.
- W2751361130 cites W2034462694 @default.
- W2751361130 cites W2037150903 @default.
- W2751361130 cites W2041489090 @default.
- W2751361130 cites W2049966052 @default.
- W2751361130 cites W2051068441 @default.
- W2751361130 cites W2053435751 @default.
- W2751361130 cites W2059241173 @default.
- W2751361130 cites W2059284624 @default.
- W2751361130 cites W2060644720 @default.
- W2751361130 cites W2060910232 @default.
- W2751361130 cites W2061831400 @default.
- W2751361130 cites W2067028423 @default.
- W2751361130 cites W2067202196 @default.
- W2751361130 cites W2070525877 @default.
- W2751361130 cites W2071536607 @default.
- W2751361130 cites W2073150015 @default.
- W2751361130 cites W2077476963 @default.
- W2751361130 cites W2083935605 @default.
- W2751361130 cites W2087578260 @default.
- W2751361130 cites W2090091203 @default.
- W2751361130 cites W2096960092 @default.
- W2751361130 cites W2102974461 @default.
- W2751361130 cites W2113422273 @default.
- W2751361130 cites W2118492858 @default.
- W2751361130 cites W2120054616 @default.
- W2751361130 cites W2120919706 @default.
- W2751361130 cites W2122812892 @default.
- W2751361130 cites W2127997119 @default.
- W2751361130 cites W2132131875 @default.
- W2751361130 cites W2133764165 @default.
- W2751361130 cites W2139639812 @default.
- W2751361130 cites W2140202284 @default.
- W2751361130 cites W2140806962 @default.
- W2751361130 cites W2147121669 @default.
- W2751361130 cites W2148260965 @default.
- W2751361130 cites W2155862946 @default.
- W2751361130 cites W2159999899 @default.
- W2751361130 cites W2164833748 @default.
- W2751361130 cites W2176782402 @default.
- W2751361130 cites W2187781852 @default.
- W2751361130 cites W2314272269 @default.
- W2751361130 cites W2317290154 @default.
- W2751361130 cites W2318459925 @default.
- W2751361130 cites W2320032044 @default.
- W2751361130 cites W2334795290 @default.
- W2751361130 cites W2347204646 @default.
- W2751361130 cites W2398878756 @default.
- W2751361130 cites W247935490 @default.
- W2751361130 cites W75132527 @default.
- W2751361130 doi "https://doi.org/10.1177/2192568217701102" @default.
- W2751361130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5721996" @default.
- W2751361130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29238646" @default.
- W2751361130 hasPublicationYear "2017" @default.
- W2751361130 type Work @default.
- W2751361130 sameAs 2751361130 @default.
- W2751361130 citedByCount "20" @default.
- W2751361130 countsByYear W27513611302018 @default.
- W2751361130 countsByYear W27513611302019 @default.
- W2751361130 countsByYear W27513611302020 @default.
- W2751361130 countsByYear W27513611302021 @default.
- W2751361130 countsByYear W27513611302022 @default.
- W2751361130 countsByYear W27513611302023 @default.
- W2751361130 crossrefType "journal-article" @default.
- W2751361130 hasAuthorship W2751361130A5035312942 @default.
- W2751361130 hasAuthorship W2751361130A5045395453 @default.