FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2751462904> ?p ?o ?g. }

• W2751462904 endingPage "1560" @default.
• W2751462904 startingPage "1553" @default.
• W2751462904 abstract "To investigate the temporal pattern and relevant associations of CSF inflammatory measures after intraventricular hemorrhage (IVH).We analyzed prospectively collected CSF cell counts and protein and glucose levels from participants in the Clot Lysis Evaluation of Accelerated Resolution of IVH phase III (CLEAR III) trial. Corrected leukocyte count and cell index were calculated to adjust for CSF leukocytes attributable to circulating blood. Data were chronologically plotted. CSF inflammatory measures (daily, mean, median, maximum, and cases with highest quartile response) were correlated with initial IVH volume, IVH clearance rate, thrombolytic treatment, bacterial infection, and adjudicated clinical outcome at 30 and 180 days.A total of 11,376 data points of CSF results from 464 trial participants were analyzed. Measures of CSF inflammatory response evolved during the resolution of IVH. This was significantly more pronounced with initial IVH volume exceeding 20 mL. Intraventricular alteplase was associated with a significantly augmented inflammatory response compared to saline, even after correcting for initial IVH volume. There was an association but nonpredictive correlation of CSF inflammation measures with culture-positive CSF bacterial infection. None of the CSF inflammatory measures, including cases with upper quartile inflammatory response, was associated with a significant detrimental effect on 30 or 180 days functional outcome or mortality after multivariate adjustment for measures of disease severity.Aseptic CSF inflammation after IVH is primarily dependent on the volume of initial bleed. Thrombolysis intensifies the inflammatory response, with no apparent detrimental effect on clinical outcome.NCT00784134." @default.
• W2751462904 created "2017-09-15" @default.
• W2751462904 creator A5004739483 @default.
• W2751462904 creator A5011179398 @default.
• W2751462904 creator A5012035250 @default.
• W2751462904 creator A5016563277 @default.
• W2751462904 creator A5022728582 @default.
• W2751462904 creator A5025030662 @default.
• W2751462904 creator A5040619239 @default.
• W2751462904 creator A5040895261 @default.
• W2751462904 creator A5043634794 @default.
• W2751462904 creator A5055304768 @default.
• W2751462904 creator A5056306171 @default.
• W2751462904 creator A5067014628 @default.
• W2751462904 creator A5073362663 @default.
• W2751462904 creator A5084117365 @default.
• W2751462904 creator A5087790193 @default.
• W2751462904 date "2017-09-08" @default.
• W2751462904 modified "2023-10-14" @default.
• W2751462904 title "CSF inflammatory response after intraventricular hemorrhage" @default.
• W2751462904 cites W1534915598 @default.
• W2751462904 cites W1611918793 @default.
• W2751462904 cites W1965069494 @default.
• W2751462904 cites W1965425898 @default.
• W2751462904 cites W1967047312 @default.
• W2751462904 cites W1977721599 @default.
• W2751462904 cites W1978690745 @default.
• W2751462904 cites W1980923279 @default.
• W2751462904 cites W1984171271 @default.
• W2751462904 cites W2003813570 @default.
• W2751462904 cites W2011252631 @default.
• W2751462904 cites W2011871200 @default.
• W2751462904 cites W2016612573 @default.
• W2751462904 cites W2038196999 @default.
• W2751462904 cites W2040585889 @default.
• W2751462904 cites W2044946346 @default.
• W2751462904 cites W2048087380 @default.
• W2751462904 cites W2051133080 @default.
• W2751462904 cites W2058323075 @default.
• W2751462904 cites W2083398834 @default.
• W2751462904 cites W2090147463 @default.
• W2751462904 cites W2094098499 @default.
• W2751462904 cites W2106544141 @default.
• W2751462904 cites W2106610228 @default.
• W2751462904 cites W2140900977 @default.
• W2751462904 cites W2160930102 @default.
• W2751462904 cites W2169259256 @default.
• W2751462904 cites W2339999090 @default.
• W2751462904 cites W2549926987 @default.
• W2751462904 cites W2728291192 @default.
• W2751462904 doi "https://doi.org/10.1212/wnl.0000000000004493" @default.
• W2751462904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5634667" @default.
• W2751462904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28887375" @default.
• W2751462904 hasPublicationYear "2017" @default.
• W2751462904 type Work @default.
• W2751462904 sameAs 2751462904 @default.
• W2751462904 citedByCount "38" @default.
• W2751462904 countsByYear W27514629042017 @default.
• W2751462904 countsByYear W27514629042018 @default.
• W2751462904 countsByYear W27514629042019 @default.
• W2751462904 countsByYear W27514629042020 @default.
• W2751462904 countsByYear W27514629042021 @default.
• W2751462904 countsByYear W27514629042022 @default.
• W2751462904 countsByYear W27514629042023 @default.
• W2751462904 crossrefType "journal-article" @default.
• W2751462904 hasAuthorship W2751462904A5004739483 @default.
• W2751462904 hasAuthorship W2751462904A5011179398 @default.
• W2751462904 hasAuthorship W2751462904A5012035250 @default.
• W2751462904 hasAuthorship W2751462904A5016563277 @default.
• W2751462904 hasAuthorship W2751462904A5022728582 @default.
• W2751462904 hasAuthorship W2751462904A5025030662 @default.
• W2751462904 hasAuthorship W2751462904A5040619239 @default.
• W2751462904 hasAuthorship W2751462904A5040895261 @default.
• W2751462904 hasAuthorship W2751462904A5043634794 @default.
• W2751462904 hasAuthorship W2751462904A5055304768 @default.
• W2751462904 hasAuthorship W2751462904A5056306171 @default.
• W2751462904 hasAuthorship W2751462904A5067014628 @default.
• W2751462904 hasAuthorship W2751462904A5073362663 @default.
• W2751462904 hasAuthorship W2751462904A5084117365 @default.
• W2751462904 hasAuthorship W2751462904A5087790193 @default.
• W2751462904 hasBestOaLocation W27514629042 @default.
• W2751462904 hasConcept C126322002 @default.
• W2751462904 hasConcept C2776914184 @default.
• W2751462904 hasConcept C2778376644 @default.
• W2751462904 hasConcept C2779234561 @default.
• W2751462904 hasConcept C2779252433 @default.
• W2751462904 hasConcept C3020196126 @default.
• W2751462904 hasConcept C44249647 @default.
• W2751462904 hasConcept C54355233 @default.
• W2751462904 hasConcept C68443243 @default.
• W2751462904 hasConcept C71924100 @default.
• W2751462904 hasConcept C86803240 @default.
• W2751462904 hasConcept C90924648 @default.
• W2751462904 hasConceptScore W2751462904C126322002 @default.
• W2751462904 hasConceptScore W2751462904C2776914184 @default.
• W2751462904 hasConceptScore W2751462904C2778376644 @default.
• W2751462904 hasConceptScore W2751462904C2779234561 @default.
• W2751462904 hasConceptScore W2751462904C2779252433 @default.

• next