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- W2751639648 abstract "Aim: To explore the complete gene networks regulated by small RNA SprC and its targets in Staphylococcus aureus. Materials & methods: The isobaric tags for relative and absolute quantitation and bioinformatic methods were utilized to identify and analyze the target proteins affected by SprC in S. aureus N315. Results: Proteomic analysis showed that the expression of 44 proteins was modulated by SprC. Further, bioinformatic analysis displayed that these affected proteins mainly associated with metabolic and cellular process, biological regulation and catalytic activity. Conclusion: Our data provide a rich resource of SprC targets in S. aureus, although the mechanism of regulation by SprC is yet to be elucidated." @default.
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- W2751639648 date "2017-10-01" @default.
- W2751639648 modified "2023-09-23" @default.
- W2751639648 title "Isobaric tags for relative and absolute quantitation proteomics analysis of gene regulation by SprC in Staphylococcus aureus" @default.
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- W2751639648 doi "https://doi.org/10.2217/fmb-2017-0033" @default.
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