FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2751777421> ?p ?o ?g. }

• W2751777421 endingPage "S273" @default.
• W2751777421 startingPage "S273" @default.
• W2751777421 abstract "The diagnosis of bullous pemphigoid (BP) relies on the detection of tissue bound or circulating in patients’ sera IgG anti-basement membrane (BMZ) autoantibodies. Despite the reported comparable titers of anti-BMZ antibodies in both serum and blister fluid of BP patients using indirect immunofluorescence on salt-split skin substrate, only scarce data exist on the detection of antibodies to the BP antigens, BP180 and BP230, using the more sensitive and specific ELISA assays. In the present study, BP180NC16A and BP230 ELISA kits were used to compare the levels of the corresponding autoantibodies in pairs serum-blister fluid collected simultaneously in 38 newly diagnosed untreated BP patients. Our aim was to investigate whether blister fluid can be an alternative to sera for detecting anti-BP180 and anti-BP230 in the routine diagnosis of BP. Positive results for anti-BP180 antibodies (cut-off 20 RU/ml) were detected in 32 and 30 sera and blister fluid samples, respectively (n = 38, Cohen’s k = 0.826) which represents a very good correlation of the results. Similarly, anti-BP230 antibodies were positive (cut-off 20 RU/ml) in the serum and blister fluid of 13 and 12 patients, respectively (n = 38, Cohen’s k = 0.821). In addition, in 17 out of 38 patients (44.7%) there was full agreement between the ELISA BP180 and BP230 results in the serum-blister fluid pairs, all positive in 12 or all negative in 5 patients, respectively. In the remaining 21 patients the blister fluid tested positive only for anti-BP180 known to be of major pathogenic importance in BP. Only 3 out of 38 blister fluid samples showed negative results for both autoantibodies, whereas the corresponding serum samples were positive either for BP180 or BP230 antibodies. Our results demonstrate a relatively high agreement between the anti-BP180 and anti-BP230 values in the pairs serum-blister fluid, the latter being less invasive and easier to obtain in the routine diagnosis of BP, especially in elderly patients or children." @default.
• W2751777421 created "2017-09-15" @default.
• W2751777421 creator A5038226640 @default.
• W2751777421 creator A5078286417 @default.
• W2751777421 creator A5087850699 @default.
• W2751777421 date "2017-10-01" @default.
• W2751777421 modified "2023-10-16" @default.
• W2751777421 title "473 A comparative study of bullous pemphigoid-180 and 230 antibodies in serum and blister fluid samples" @default.
• W2751777421 doi "https://doi.org/10.1016/j.jid.2017.07.669" @default.
• W2751777421 hasPublicationYear "2017" @default.
• W2751777421 type Work @default.
• W2751777421 sameAs 2751777421 @default.
• W2751777421 citedByCount "0" @default.
• W2751777421 crossrefType "journal-article" @default.
• W2751777421 hasAuthorship W2751777421A5038226640 @default.
• W2751777421 hasAuthorship W2751777421A5078286417 @default.
• W2751777421 hasAuthorship W2751777421A5087850699 @default.
• W2751777421 hasBestOaLocation W27517774211 @default.
• W2751777421 hasConcept C142724271 @default.
• W2751777421 hasConcept C147483822 @default.
• W2751777421 hasConcept C159654299 @default.
• W2751777421 hasConcept C163764329 @default.
• W2751777421 hasConcept C203014093 @default.
• W2751777421 hasConcept C2778075117 @default.
• W2751777421 hasConcept C2778236600 @default.
• W2751777421 hasConcept C2779252107 @default.
• W2751777421 hasConcept C2984894117 @default.
• W2751777421 hasConcept C32611913 @default.
• W2751777421 hasConcept C71924100 @default.
• W2751777421 hasConceptScore W2751777421C142724271 @default.
• W2751777421 hasConceptScore W2751777421C147483822 @default.
• W2751777421 hasConceptScore W2751777421C159654299 @default.
• W2751777421 hasConceptScore W2751777421C163764329 @default.
• W2751777421 hasConceptScore W2751777421C203014093 @default.
• W2751777421 hasConceptScore W2751777421C2778075117 @default.
• W2751777421 hasConceptScore W2751777421C2778236600 @default.
• W2751777421 hasConceptScore W2751777421C2779252107 @default.
• W2751777421 hasConceptScore W2751777421C2984894117 @default.
• W2751777421 hasConceptScore W2751777421C32611913 @default.
• W2751777421 hasConceptScore W2751777421C71924100 @default.
• W2751777421 hasIssue "10" @default.
• W2751777421 hasLocation W27517774211 @default.
• W2751777421 hasLocation W27517774212 @default.
• W2751777421 hasOpenAccess W2751777421 @default.
• W2751777421 hasPrimaryLocation W27517774211 @default.
• W2751777421 hasRelatedWork W2004634456 @default.
• W2751777421 hasRelatedWork W2005537564 @default.
• W2751777421 hasRelatedWork W2014901103 @default.
• W2751777421 hasRelatedWork W2037292226 @default.
• W2751777421 hasRelatedWork W2122130153 @default.
• W2751777421 hasRelatedWork W2135902875 @default.
• W2751777421 hasRelatedWork W2414958781 @default.
• W2751777421 hasRelatedWork W2420728863 @default.
• W2751777421 hasRelatedWork W53214839 @default.
• W2751777421 hasRelatedWork W3031994139 @default.
• W2751777421 hasVolume "137" @default.
• W2751777421 isParatext "false" @default.
• W2751777421 isRetracted "false" @default.
• W2751777421 magId "2751777421" @default.
• W2751777421 workType "article" @default.