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- W2751844625 abstract "ObjectiveTo investigate the association of aggressive violent behavior and related short tandem repeats (STRs) loci by the analysis of 15 STRs loci genetic polymorphism.MethodsThe biological samples of 203 persons with aggressive violent behaviors and 207 healthy persons without violent behavior were collected. Then the DNA sample was amplified by AmpFlSTR IdentifilerTM system and separated by electrophoresis to compare the genotypes and alleles of 15 STRs gene frequencies in the two groups.ResultsAll the 15 STRs loci in people with aggressive violent behavior and healthy people were found to coincide with Hardy-Weinberg equilibrium (P>0.05). There was a significant difference in distributing of allele frequency of THO1 and TPOX between people with aggressive violent behaviors and healthy people (P 0.05）.ConclusionThe genetic polymorphism of THO1 and TPOX loci may be associated with the aggressive violent behaviors，and the allele 10 of THO1, allele 11 of TPOX may be the genetic factor to aggressive violent behavior.Key words: Passive-aggressive personality disorder; Chromosomes, human; Microsatellites repeats; Polymorphism，genetic; Case-control studies" @default.
- W2751844625 created "2017-09-15" @default.
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- W2751844625 date "2012-04-05" @default.
- W2751844625 modified "2023-09-22" @default.
- W2751844625 title "Association study of the genetic polymorphism of fifteen short tandem repeats loci and aggressive violent behavior" @default.
- W2751844625 doi "https://doi.org/10.3760/cma.j.issn.1006-7884.2012.02.007" @default.
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