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- W2752071446 abstract "ObjectiveTo observe the change of wrists and fingers of patients with rheumatoid arthritis(RA) in the moderately severe active period before and after treatment by high frequency power Doppler ultrasound, and analyze relationship between ultrasound parameter and other clinical indexes.MethodsThirty-five patients with moderately severe active period of RA were involved. Ultrasonography were performed to scan wrists and fingers of RA patients at baseline, 3 months and 6 months after treatment. The synovial membrane, flexor/extensor tendon sheath, power Doppler signal and bone cortex were observed. At the same time, clinical indexes, laboratory indicators, visual analog scale(VAS), 28-joint disease activity score(DAS28) and health assessment questionnaire(HAQ) were recorded.ResultsCompared with those befor treatment, tender joint count(TJC), swollen joint count(SJC), erythrocyte sedimentation rate (ESR), C reactive protein (CRP), VAS, DAS28, HAQ were reduced and hypertrophic synovium, synovitis and tenosynovitis scores were also improved after treatment. There were significant correlation between hypertrophic synovium, synovitis, tenosynovitis scores and DAS28, CRP. Bone erosion was correlated with CRP before treatment, and were correlated with CRP, DAS28, HAQ after treatment.ConclusionsHypertrophic synovium, synovitis, tenosynovitis can evaluate curative efficacy in moderately severe active period of RA patients.Key words: Ultrasonography, Doppler; Arthritis, rheumatoid; Treatment outcome" @default.
- W2752071446 created "2017-09-15" @default.
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- W2752071446 date "2016-08-25" @default.
- W2752071446 modified "2023-09-25" @default.
- W2752071446 title "Evaluation of curative effect of rheumatoid arthritis in the moderately severe active period by high frequency power Doppler ultrasound" @default.
- W2752071446 doi "https://doi.org/10.3760/cma.j.issn.1004-4477.2016.08.017" @default.
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