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- W2752453328 abstract "Hodgkin lymphoma (HL) is curable in 70-80% of patients with first-line therapy. However, relapses occur in a minority of patients with favorable early stage disease and are more frequent in patients with advanced HL. Salvage chemotherapy followed by high-dose chemotherapy and autologous stem cell transplant (ASCT) for patients with chemotherapy-sensitive disease is a standard treatment sequence for relapsed or refractory (rel/ref) HL. Patients who achieve complete response prior to ASCT have better survival outcomes. The choice of salvage chemotherapy therapy is becoming increasingly difficult in the era of novel agents, as there are no randomized studies to guide the choice of a second-line regimen. In this article, we will review current salvage therapy options, including combination chemotherapy and novel-agent-based salvage regimens for rel/ref HL." @default.
- W2752453328 created "2017-09-15" @default.
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- W2752453328 date "2017-08-29" @default.
- W2752453328 modified "2023-10-18" @default.
- W2752453328 title "Current strategies for salvage treatment for relapsed classical Hodgkin lymphoma" @default.
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- W2752453328 doi "https://doi.org/10.1177/2040620717728000" @default.
- W2752453328 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5638176" @default.
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