FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2752585393> ?p ?o ?g. }

• W2752585393 abstract "Instrument and technique development and modeling of ionization methods using infrared (IR) laser desorption and ablation for mass spectrometry (MS) analysis of chemical and biochemical samples are described. Infrared lasers are highly efficient at sample removal and post-ablation ionization of materials removed by IR laser can be used to improve ionization efficiency. Fundamental studies of the physical processes in laser ablation mass spectrometry can help elucidate the mechanism. In this research, an infrared/ultraviolet two-laser matrix-assisted laser desorption ionization (MALDI) MS was developed for analysis of biomolecules. An infrared laser was used to ablate a mixture of analyte and matrix, and the ablated material was post-ionized by an ultraviolet (UV) laser. Factors affecting ion yield, including IR and UV laser fluences and the delay time between the laser pulses, were studied using a peptide standard. Protein samples were tested and the observed signals suggested that ionization occurs through a UV MALDI mechanism. A continuous flow infrared matrix-assisted laser desorption electrospray ionization (CF IR MALDESI) mass spectrometry was developed for study of chemical and biochemical reactions. Samples in aqueous solution were flowed through a silica capillary to form a liquid bead at the capillary tip. An IR laser was used for sample ablation and the ejected sample was entrained in an electrospray to form ions. Ions were sent to an ion trap mass spectrometer for analysis. The chelation reaction of 1,10-phenanthroline with iron (II), the denaturation reaction of insulin with 1,4-dithiothreitol, and tryptic digestion of cytochrome c were on-line monitored. A two-dimensional finite element model was developed to simulate IR laser ablation of glycerol. The laser fluence was varied from 1 to 6 kJ/m2, and the wavelength was varied from 2.7 – 3.7 µm that covered the OH and CH stretch absorption region of glycerol. The results showed a strong temperature dependence on laser wavelength and fluence. The peak temperature of glycerol was obtained as the laser wavelength tuned to OH stretch absorption at 3 µm, and was sufficient for phase explosion to occur. The simulation results showed a good agreement with previous particle sizing and plume imaging results." @default.
• W2752585393 created "2017-09-15" @default.
• W2752585393 creator A5070427740 @default.
• W2752585393 date "2022-06-10" @default.
• W2752585393 modified "2023-10-15" @default.
• W2752585393 title "Infrared laser ablation for biological mass spectrometry" @default.
• W2752585393 cites W1497508684 @default.
• W2752585393 cites W1520098629 @default.
• W2752585393 cites W1606248456 @default.
• W2752585393 cites W1650743766 @default.
• W2752585393 cites W1662114404 @default.
• W2752585393 cites W1963645511 @default.
• W2752585393 cites W1964021392 @default.
• W2752585393 cites W1964907417 @default.
• W2752585393 cites W1967907887 @default.
• W2752585393 cites W1969290129 @default.
• W2752585393 cites W1972050584 @default.
• W2752585393 cites W1972808096 @default.
• W2752585393 cites W1974732006 @default.
• W2752585393 cites W1974830441 @default.
• W2752585393 cites W1978659737 @default.
• W2752585393 cites W1980346428 @default.
• W2752585393 cites W1980776679 @default.
• W2752585393 cites W1981781693 @default.
• W2752585393 cites W1983335448 @default.
• W2752585393 cites W1983996314 @default.
• W2752585393 cites W1984541138 @default.
• W2752585393 cites W1984806658 @default.
• W2752585393 cites W1985973605 @default.
• W2752585393 cites W1986693684 @default.
• W2752585393 cites W1987320735 @default.
• W2752585393 cites W1988330065 @default.
• W2752585393 cites W1990206893 @default.
• W2752585393 cites W1990917480 @default.
• W2752585393 cites W1992802768 @default.
• W2752585393 cites W1993191718 @default.
• W2752585393 cites W1994789201 @default.
• W2752585393 cites W1994984489 @default.
• W2752585393 cites W1995382705 @default.
• W2752585393 cites W1996076449 @default.
• W2752585393 cites W1998192315 @default.
• W2752585393 cites W1999201825 @default.
• W2752585393 cites W1999312098 @default.
• W2752585393 cites W1999365897 @default.
• W2752585393 cites W2001130657 @default.
• W2752585393 cites W2002203811 @default.
• W2752585393 cites W2002603327 @default.
• W2752585393 cites W2004627688 @default.
• W2752585393 cites W2006146101 @default.
• W2752585393 cites W2007305775 @default.
• W2752585393 cites W2007661953 @default.
• W2752585393 cites W2013915244 @default.
• W2752585393 cites W2015855282 @default.
• W2752585393 cites W2016642215 @default.
• W2752585393 cites W2020472469 @default.
• W2752585393 cites W2022042587 @default.
• W2752585393 cites W2022850426 @default.
• W2752585393 cites W2023698910 @default.
• W2752585393 cites W2025085133 @default.
• W2752585393 cites W2026916042 @default.
• W2752585393 cites W2028811987 @default.
• W2752585393 cites W2029101457 @default.
• W2752585393 cites W2029644425 @default.
• W2752585393 cites W2032301089 @default.
• W2752585393 cites W2032311781 @default.
• W2752585393 cites W2032380575 @default.
• W2752585393 cites W2033770857 @default.
• W2752585393 cites W2034904963 @default.
• W2752585393 cites W2036945414 @default.
• W2752585393 cites W2039392102 @default.
• W2752585393 cites W2040385608 @default.
• W2752585393 cites W2040677997 @default.
• W2752585393 cites W2040879180 @default.
• W2752585393 cites W2041496236 @default.
• W2752585393 cites W2043675566 @default.
• W2752585393 cites W2044811560 @default.
• W2752585393 cites W2044835288 @default.
• W2752585393 cites W2044899072 @default.
• W2752585393 cites W2045411758 @default.
• W2752585393 cites W2046382043 @default.
• W2752585393 cites W2047824610 @default.
• W2752585393 cites W2048795280 @default.
• W2752585393 cites W2050565280 @default.
• W2752585393 cites W2051746356 @default.
• W2752585393 cites W2053055288 @default.
• W2752585393 cites W2053591916 @default.
• W2752585393 cites W2053618747 @default.
• W2752585393 cites W2054970731 @default.
• W2752585393 cites W2055243355 @default.
• W2752585393 cites W2055954673 @default.
• W2752585393 cites W2057940370 @default.
• W2752585393 cites W2058340084 @default.
• W2752585393 cites W2060887762 @default.
• W2752585393 cites W2061085456 @default.
• W2752585393 cites W2063142894 @default.
• W2752585393 cites W2063542815 @default.
• W2752585393 cites W2063556676 @default.
• W2752585393 cites W2071044837 @default.
• W2752585393 cites W2071255171 @default.
• W2752585393 cites W2071323592 @default.

• next