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- W2752602654 abstract "Granulocytic sarcoma is a rare extramedullary tumor composed ofimmature myeloid cells. It is usually associated with leukemia or othermyeloproliferative disorders but can also occur without overthematologic diseases. The breast is an uncommon site of presentationand requires a high index of suspicion for diagnosis. We report such acase in a 45-year-old female, who presented with nontender left breastlump of 6 months' duration. A peripheral smear and bone marrowexamination at that time was normal. A lumpectomy was done. An H and Ediagnosis of lobular carcinoma vs. non-Hodgkin's lymphoma wasentertained. Immunostains, however, revealed myeloperoxidase, naphtholAS-D chloroacetate esterase and CD43 positivity, indicating a diagnosisof granulocytic sarcoma. It appears that early initiation of systemicAML-type chemotherapy is beneficial and may delay or avert thedevelopment of AML in bone marrow and blood. Eight months later, thepatient presented with an orbital mass; bone marrow and peripheralsmear involvement by AML." @default.
- W2752602654 created "2017-09-15" @default.
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- W2752602654 date "2007-03-28" @default.
- W2752602654 modified "2023-09-26" @default.
- W2752602654 title "Case Report - Granulocytic sarcoma of breast: An aleukemic presentation" @default.
- W2752602654 hasPublicationYear "2007" @default.
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