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- W2752702588 abstract "During an asthma attack, drugs such as salbutamol can help a person breathe easy by turning on a protein receptor that triggers the opening of the lung’s airways. According to a new study, drugs targeting this receptor might have another, unrelated benefit: reducing the risk of Parkinson’s disease (Science 2017, DOI: 10.1126/science.aaf3934). “It’s an exciting clue” that could point the way toward new treatments for the neurodegenerative disease, says Clemens Scherzer of Brigham & Women’s Hospital and Harvard Medical School, who led the research team. The findings connect the receptor targeted by asthma drugs to the expression of the gene that encodes the protein α-synuclein. In the brains of people with Parkinson’s, this protein aggregates and forms characteristic clumps. Scientists are working on therapies to clear toxic forms of the protein from the brain. But, Scherzer says, scientists still debate which form of α-synuclein is the toxic one. He and" @default.
- W2752702588 created "2017-09-15" @default.
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- W2752702588 date "2017-09-04" @default.
- W2752702588 modified "2023-10-16" @default.
- W2752702588 title "Asthma drugs may reduce Parkinson’s risk" @default.
- W2752702588 doi "https://doi.org/10.1021/cen-09535-notw5" @default.
- W2752702588 hasPublicationYear "2017" @default.
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