Matches in SemOpenAlex for { <https://semopenalex.org/work/W2753073951> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2753073951 endingPage "1098" @default.
- W2753073951 startingPage "1095" @default.
- W2753073951 abstract "To investigate the value of serum inhibin B (InhB) in predicting the results of testicular sperm extraction (TESE) in patients with azoospermia.This study included 191 cases of obstructive azoospermia (OA), 360 cases of nonobstructive azoospermia (NOA), and 100 male controls with normal semen parameters. According to whether sperm was found in TESE, the NOA patients were divided into a sperm-absence group (TESE－, n=127) and a sperm-presence group (TESE+, n=233). Blood samples were collected from the subjects between 8:00 and 10:00 am for measurement of the levels of serum InhB. The specificity and sensitivity of serum InhB predicting TESE outcome were analyzed with receiver operating characteristics curve (ROC).The serum InhB level was significantly lower in the TESE－ group (［19.7±34.8］ pg/ml) than in the OA (［106.8±66.2］ pg/ml), TESE+ (［98.2±62.4］ pg/ml) and normal control group (［108.3±65.0］ pg/ml) (P<0.01), but there were no statistically significant differences among the latter three groups (P>0.05). Analysis of ROC showed that the best cut-off value of serum InhB was 19.1 pg/ml. Under the cut-off value, AUCROC was 0.88, specificity 84.2%, sensitivity 90.1%, and accuracy 88.1%.The serum InhB level is a good and non-invasively obtained index of spermatogenesis and should be measured for predicting the results of TESE.目的： 探讨血清抑制素 B（INHB）检测在无精子症患者经睾丸抽吸术（TESE）结局预评估中的意义。 方法： 根据研究需要将受试者分为3组：梗阻性无精子症（OA）组（n=191)，非梗阻性无精子症（NOA）组（n=360）,精液参数正常对照组（n=100）。NOA组根据TESE结局分为TESE无精子组(TESE－,n=127)和TESE有精子组(TESE+,n=233)。血液标本均于上午8:00~10:00收集，测定其INHB值。 采用受试者工作特征曲线(ROC)分析评价血清INHB预测TESE结局的敏感性和特异性。 结果： TESE－组的血清INHB水平［(19.7±34.8) pg/ml］显著低于OA组［(106.8±66.2) pg/ml］、TESE+组［(98.2±62.4) pg/ml］及精液参数正常对照组［(108.3±65.0) pg/ml］（P<0.01)，TESE+组的血清INHB水平与OA组、精液参数正常对照组无显著性差异（P>0.05)。ROC曲线分析显示，血清INHB最佳分割点为19.1 pg/ml，此时ROC曲线下面积(AUCROC)为0.88，敏感性为90.1%，特异性为84.2%，诊断准确性达88.1%。结论： 血清INHB是一种良好的非侵入性的精子生成预测指标，无精子症患者TESE前应该常规行血清INHB检测以评估其TESE结局。." @default.
- W2753073951 created "2017-09-15" @default.
- W2753073951 creator A5011887817 @default.
- W2753073951 creator A5015422657 @default.
- W2753073951 creator A5025010750 @default.
- W2753073951 creator A5033098447 @default.
- W2753073951 creator A5053011514 @default.
- W2753073951 date "2016-12-01" @default.
- W2753073951 modified "2023-09-23" @default.
- W2753073951 title "[Level of serum inhibin B for predicting the results of testicular sperm extraction in azoospermia patients]." @default.
- W2753073951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29282914" @default.
- W2753073951 hasPublicationYear "2016" @default.
- W2753073951 type Work @default.
- W2753073951 sameAs 2753073951 @default.
- W2753073951 citedByCount "0" @default.
- W2753073951 crossrefType "journal-article" @default.
- W2753073951 hasAuthorship W2753073951A5011887817 @default.
- W2753073951 hasAuthorship W2753073951A5015422657 @default.
- W2753073951 hasAuthorship W2753073951A5025010750 @default.
- W2753073951 hasAuthorship W2753073951A5033098447 @default.
- W2753073951 hasAuthorship W2753073951A5053011514 @default.
- W2753073951 hasConcept C123765429 @default.
- W2753073951 hasConcept C126322002 @default.
- W2753073951 hasConcept C126894567 @default.
- W2753073951 hasConcept C16685009 @default.
- W2753073951 hasConcept C2777420699 @default.
- W2753073951 hasConcept C2777688143 @default.
- W2753073951 hasConcept C2778093475 @default.
- W2753073951 hasConcept C2779234561 @default.
- W2753073951 hasConcept C2781087480 @default.
- W2753073951 hasConcept C29456083 @default.
- W2753073951 hasConcept C3018711027 @default.
- W2753073951 hasConcept C35035537 @default.
- W2753073951 hasConcept C54355233 @default.
- W2753073951 hasConcept C58471807 @default.
- W2753073951 hasConcept C71924100 @default.
- W2753073951 hasConcept C86803240 @default.
- W2753073951 hasConceptScore W2753073951C123765429 @default.
- W2753073951 hasConceptScore W2753073951C126322002 @default.
- W2753073951 hasConceptScore W2753073951C126894567 @default.
- W2753073951 hasConceptScore W2753073951C16685009 @default.
- W2753073951 hasConceptScore W2753073951C2777420699 @default.
- W2753073951 hasConceptScore W2753073951C2777688143 @default.
- W2753073951 hasConceptScore W2753073951C2778093475 @default.
- W2753073951 hasConceptScore W2753073951C2779234561 @default.
- W2753073951 hasConceptScore W2753073951C2781087480 @default.
- W2753073951 hasConceptScore W2753073951C29456083 @default.
- W2753073951 hasConceptScore W2753073951C3018711027 @default.
- W2753073951 hasConceptScore W2753073951C35035537 @default.
- W2753073951 hasConceptScore W2753073951C54355233 @default.
- W2753073951 hasConceptScore W2753073951C58471807 @default.
- W2753073951 hasConceptScore W2753073951C71924100 @default.
- W2753073951 hasConceptScore W2753073951C86803240 @default.
- W2753073951 hasIssue "12" @default.
- W2753073951 hasLocation W27530739511 @default.
- W2753073951 hasOpenAccess W2753073951 @default.
- W2753073951 hasPrimaryLocation W27530739511 @default.
- W2753073951 hasRelatedWork W124409614 @default.
- W2753073951 hasRelatedWork W2021447344 @default.
- W2753073951 hasRelatedWork W2046597038 @default.
- W2753073951 hasRelatedWork W2054660932 @default.
- W2753073951 hasRelatedWork W2185638398 @default.
- W2753073951 hasRelatedWork W2260672927 @default.
- W2753073951 hasRelatedWork W2372998219 @default.
- W2753073951 hasRelatedWork W2387983349 @default.
- W2753073951 hasRelatedWork W2388627257 @default.
- W2753073951 hasRelatedWork W2404968987 @default.
- W2753073951 hasRelatedWork W2465650527 @default.
- W2753073951 hasRelatedWork W2503026489 @default.
- W2753073951 hasRelatedWork W2605759983 @default.
- W2753073951 hasRelatedWork W2744834612 @default.
- W2753073951 hasRelatedWork W2903291928 @default.
- W2753073951 hasRelatedWork W2939197740 @default.
- W2753073951 hasRelatedWork W2958787261 @default.
- W2753073951 hasRelatedWork W2986894676 @default.
- W2753073951 hasRelatedWork W3124018425 @default.
- W2753073951 hasRelatedWork W804746708 @default.
- W2753073951 hasVolume "22" @default.
- W2753073951 isParatext "false" @default.
- W2753073951 isRetracted "false" @default.
- W2753073951 magId "2753073951" @default.
- W2753073951 workType "article" @default.