Matches in SemOpenAlex for { <https://semopenalex.org/work/W2753325495> ?p ?o ?g. }
- W2753325495 abstract "Our current understanding of cardiac excitation and its coupling to contraction is largely based on ex vivo studies utilising fluorescent organic dyes to assess cardiac action potentials and signal transduction. Recent advances in optogenetic sensors open exciting new possibilities for cardiac research and allow us to answer research questions that cannot be addressed using the classic organic dyes. Especially thrilling is the possibility to use optogenetic sensors to record parameters of cardiac excitation and contraction in vivo. In addition, optogenetics provide a high spatial resolution, as sensors can be coupled to motifs and targeted to specific cell types and subcellular domains of the heart. In this review, we will give a comprehensive overview of relevant optogenetic sensors, how they can be utilised in cardiac research and how they have been applied in cardiac research up to now." @default.
- W2753325495 created "2017-09-15" @default.
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- W2753325495 creator A5068162834 @default.
- W2753325495 creator A5083773371 @default.
- W2753325495 date "2017-08-31" @default.
- W2753325495 modified "2023-10-16" @default.
- W2753325495 title "Cardiac optogenetics: using light to monitor cardiac physiology" @default.
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- W2753325495 doi "https://doi.org/10.1007/s00395-017-0645-y" @default.
- W2753325495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5579185" @default.
- W2753325495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28861604" @default.
- W2753325495 hasPublicationYear "2017" @default.
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