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- W2753372908 abstract "Clec12a is a largely uncharacterized C-type lectin receptor with an immunoreceptor tyrosine-based inhibition motif. A Clec12a-deficient mouse model was generated in order to investigate the physiological role of Clec12a. Clec12a is dispensable for myeloid and lymphoid cell development under homeostatic conditions, and for the initiation of immune responses to all tested microbial-derived PAMPs. Clec12a is required for the regulation of inflammation in response to sterile cell death and sensing of uric acid crystals, with implications for autoimmunity and inflammatory diseases." @default.
- W2753372908 created "2017-09-15" @default.
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- W2753372908 date "2014-01-01" @default.
- W2753372908 modified "2023-09-26" @default.
- W2753372908 title "Generation and analysis of a Clec12a-deficient mouse model" @default.
- W2753372908 hasPublicationYear "2014" @default.
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