Matches in SemOpenAlex for { <https://semopenalex.org/work/W2753648728> ?p ?o ?g. }
- W2753648728 endingPage "173" @default.
- W2753648728 startingPage "155" @default.
- W2753648728 abstract "Model organisms are widely used in research that is ultimately aimed at understanding the causes and consequences of human disease. It may seem counterintuitive to expect clinically useful information to be obtained from species as diverse as fishes and insects, but because fundamental biological mechanisms share evolutionary origins they transcend species barriers. Epigenetic mechanisms fulfil this expectation admirably as more and more is discovered about the basic operational rules of inheritance, which are much more elaborate than formerly thought. Only a few decades ago, although the complex interplay between genes, inheritance and the environment was recognized, it was difficult to explain. Recent discoveries about the controlling influences of gene silencing through DNA and histone methylation, the roles of so-called non-coding DNA and microRNA, and the way in which these factors respond to environmental conditions have started to shed light on these basic mechanisms. Diverse model species allow epigenetic mechanisms to be studied from different perspectives; for example, some are better suited to studies of sex determination while others may be more convenient for studying the earliest stages of organ development, growth and the influence of nutrition on future wellbeing. The rationale for including this chapter in a book that is focused on uncovering relationships between periconception nutrition in humans is to highlight the opportunities and insights that may be gained by focusing attention on studies in non-mammalian model species." @default.
- W2753648728 created "2017-09-15" @default.
- W2753648728 creator A5008547914 @default.
- W2753648728 date "2017-01-01" @default.
- W2753648728 modified "2023-09-23" @default.
- W2753648728 title "Exploitation of Non-mammalian Model Organisms in Epigenetic Research" @default.
- W2753648728 cites W1420514769 @default.
- W2753648728 cites W1497336969 @default.
- W2753648728 cites W1504041703 @default.
- W2753648728 cites W1511926043 @default.
- W2753648728 cites W1519202369 @default.
- W2753648728 cites W1529532448 @default.
- W2753648728 cites W1568932783 @default.
- W2753648728 cites W1576742444 @default.
- W2753648728 cites W1587808549 @default.
- W2753648728 cites W1655353685 @default.
- W2753648728 cites W1862666278 @default.
- W2753648728 cites W1963785180 @default.
- W2753648728 cites W1969429580 @default.
- W2753648728 cites W1971010535 @default.
- W2753648728 cites W1972474711 @default.
- W2753648728 cites W1982690749 @default.
- W2753648728 cites W1985576540 @default.
- W2753648728 cites W1986622938 @default.
- W2753648728 cites W1987375811 @default.
- W2753648728 cites W1994908837 @default.
- W2753648728 cites W2000375923 @default.
- W2753648728 cites W2002830755 @default.
- W2753648728 cites W2007733726 @default.
- W2753648728 cites W2009340001 @default.
- W2753648728 cites W2010894254 @default.
- W2753648728 cites W2011150806 @default.
- W2753648728 cites W2014553168 @default.
- W2753648728 cites W2022574340 @default.
- W2753648728 cites W2027138325 @default.
- W2753648728 cites W2030172543 @default.
- W2753648728 cites W2033026475 @default.
- W2753648728 cites W2033237462 @default.
- W2753648728 cites W2034428614 @default.
- W2753648728 cites W2034512154 @default.
- W2753648728 cites W2044401234 @default.
- W2753648728 cites W2048296225 @default.
- W2753648728 cites W2054070560 @default.
- W2753648728 cites W2056012554 @default.
- W2753648728 cites W2059365427 @default.
- W2753648728 cites W2059964587 @default.
- W2753648728 cites W2065294830 @default.
- W2753648728 cites W2065365453 @default.
- W2753648728 cites W2065525499 @default.
- W2753648728 cites W2066431595 @default.
- W2753648728 cites W2067149182 @default.
- W2753648728 cites W2069122810 @default.
- W2753648728 cites W2070528759 @default.
- W2753648728 cites W2072829167 @default.
- W2753648728 cites W2073655252 @default.
- W2753648728 cites W2079346928 @default.
- W2753648728 cites W2079489819 @default.
- W2753648728 cites W2091903381 @default.
- W2753648728 cites W2092529046 @default.
- W2753648728 cites W2092852907 @default.
- W2753648728 cites W2095170442 @default.
- W2753648728 cites W2100462687 @default.
- W2753648728 cites W2102721981 @default.
- W2753648728 cites W2103736493 @default.
- W2753648728 cites W2106898876 @default.
- W2753648728 cites W2106909551 @default.
- W2753648728 cites W2111381054 @default.
- W2753648728 cites W2113535093 @default.
- W2753648728 cites W2125076027 @default.
- W2753648728 cites W2134748701 @default.
- W2753648728 cites W2134868253 @default.
- W2753648728 cites W2135396506 @default.
- W2753648728 cites W2137168087 @default.
- W2753648728 cites W2139639851 @default.
- W2753648728 cites W2140666900 @default.
- W2753648728 cites W2142382298 @default.
- W2753648728 cites W2143558266 @default.
- W2753648728 cites W2143955569 @default.
- W2753648728 cites W2145905670 @default.
- W2753648728 cites W2146562627 @default.
- W2753648728 cites W2149149525 @default.
- W2753648728 cites W2150761291 @default.
- W2753648728 cites W2154944962 @default.
- W2753648728 cites W2156675957 @default.
- W2753648728 cites W2162989712 @default.
- W2753648728 cites W2163644152 @default.
- W2753648728 cites W2164404896 @default.
- W2753648728 cites W2165967121 @default.
- W2753648728 cites W2166167805 @default.
- W2753648728 cites W2166542953 @default.
- W2753648728 cites W2167535325 @default.
- W2753648728 cites W2175842617 @default.
- W2753648728 cites W2221030794 @default.
- W2753648728 cites W2228244355 @default.
- W2753648728 cites W2241941008 @default.
- W2753648728 cites W2243947518 @default.
- W2753648728 cites W2254852224 @default.
- W2753648728 cites W2256261253 @default.