Matches in SemOpenAlex for { <https://semopenalex.org/work/W2753867490> ?p ?o ?g. }
- W2753867490 endingPage "e0183677" @default.
- W2753867490 startingPage "e0183677" @default.
- W2753867490 abstract "A cable model that includes polarization-induced capacitive current is derived for modeling the solitonic conduction of electrotonic potentials in neuronal branchlets with microstructure containing endoplasmic membranes. A solution of the nonlinear cable equation modified for fissured intracellular medium with a source term representing charge 'soakage' is used to show how intracellular capacitive effects of bound electrical charges within mitochondrial membranes can influence electrotonic signals expressed as solitary waves. The elastic collision resulting from a head-on collision of two solitary waves results in localized and non-dispersing electrical solitons created by the nonlinearity of the source term. It has been shown that solitons in neurons with mitochondrial membrane and quasi-electrostatic interactions of charges held by the microstructure (i.e., charge 'soakage') have a slower velocity of propagation compared with solitons in neurons with microstructure, but without endoplasmic membranes. When the equilibrium potential is a small deviation from rest, the nonohmic conductance acts as a leaky channel and the solitons are small compared when the equilibrium potential is large and the outer mitochondrial membrane acts as an amplifier, boosting the amplitude of the endogenously generated solitons. These findings demonstrate a functional role of quasi-electrostatic interactions of bound electrical charges held by microstructure for sustaining solitons with robust self-regulation in their amplitude through changes in the mitochondrial membrane equilibrium potential. The implication of our results indicate that a phenomenological description of ionic current can be successfully modeled with displacement current in Maxwell's equations as a conduction process involving quasi-electrostatic interactions without the inclusion of diffusive current. This is the first study in which solitonic conduction of electrotonic potentials are generated by polarization-induced capacitive current in microstructure and nonohmic mitochondrial membrane current." @default.
- W2753867490 created "2017-09-15" @default.
- W2753867490 creator A5010545314 @default.
- W2753867490 creator A5012569641 @default.
- W2753867490 creator A5014541617 @default.
- W2753867490 creator A5053404607 @default.
- W2753867490 creator A5057618056 @default.
- W2753867490 creator A5057661894 @default.
- W2753867490 creator A5076833026 @default.
- W2753867490 date "2017-09-07" @default.
- W2753867490 modified "2023-10-15" @default.
- W2753867490 title "Induced mitochondrial membrane potential for modeling solitonic conduction of electrotonic signals" @default.
- W2753867490 cites W1598892278 @default.
- W2753867490 cites W1633315028 @default.
- W2753867490 cites W1966154362 @default.
- W2753867490 cites W1968429775 @default.
- W2753867490 cites W1973120886 @default.
- W2753867490 cites W1981783876 @default.
- W2753867490 cites W1985454023 @default.
- W2753867490 cites W1985563324 @default.
- W2753867490 cites W1985940938 @default.
- W2753867490 cites W1986962390 @default.
- W2753867490 cites W1990681678 @default.
- W2753867490 cites W1991214313 @default.
- W2753867490 cites W2006155705 @default.
- W2753867490 cites W2008263877 @default.
- W2753867490 cites W2009375605 @default.
- W2753867490 cites W2009624432 @default.
- W2753867490 cites W2010818823 @default.
- W2753867490 cites W2017783331 @default.
- W2753867490 cites W2023192221 @default.
- W2753867490 cites W2037013349 @default.
- W2753867490 cites W2042990234 @default.
- W2753867490 cites W2044090667 @default.
- W2753867490 cites W2052814563 @default.
- W2753867490 cites W2060650941 @default.
- W2753867490 cites W2075538829 @default.
- W2753867490 cites W2077807867 @default.
- W2753867490 cites W2082106205 @default.
- W2753867490 cites W2084457009 @default.
- W2753867490 cites W2088668758 @default.
- W2753867490 cites W2089394676 @default.
- W2753867490 cites W2092520818 @default.
- W2753867490 cites W2118542498 @default.
- W2753867490 cites W2120050620 @default.
- W2753867490 cites W2122576752 @default.
- W2753867490 cites W2141194930 @default.
- W2753867490 cites W2141479374 @default.
- W2753867490 cites W2141590717 @default.
- W2753867490 cites W2149565372 @default.
- W2753867490 cites W2152781875 @default.
- W2753867490 cites W2153662862 @default.
- W2753867490 cites W2170639136 @default.
- W2753867490 cites W2174844779 @default.
- W2753867490 cites W2187576980 @default.
- W2753867490 cites W2226479614 @default.
- W2753867490 cites W2336127465 @default.
- W2753867490 cites W2585585541 @default.
- W2753867490 cites W2618770137 @default.
- W2753867490 cites W2768526693 @default.
- W2753867490 doi "https://doi.org/10.1371/journal.pone.0183677" @default.
- W2753867490 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5589106" @default.
- W2753867490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28880876" @default.
- W2753867490 hasPublicationYear "2017" @default.
- W2753867490 type Work @default.
- W2753867490 sameAs 2753867490 @default.
- W2753867490 citedByCount "8" @default.
- W2753867490 countsByYear W27538674902017 @default.
- W2753867490 countsByYear W27538674902018 @default.
- W2753867490 countsByYear W27538674902019 @default.
- W2753867490 countsByYear W27538674902020 @default.
- W2753867490 countsByYear W27538674902022 @default.
- W2753867490 crossrefType "journal-article" @default.
- W2753867490 hasAuthorship W2753867490A5010545314 @default.
- W2753867490 hasAuthorship W2753867490A5012569641 @default.
- W2753867490 hasAuthorship W2753867490A5014541617 @default.
- W2753867490 hasAuthorship W2753867490A5053404607 @default.
- W2753867490 hasAuthorship W2753867490A5057618056 @default.
- W2753867490 hasAuthorship W2753867490A5057661894 @default.
- W2753867490 hasAuthorship W2753867490A5076833026 @default.
- W2753867490 hasBestOaLocation W27538674901 @default.
- W2753867490 hasConcept C101142426 @default.
- W2753867490 hasConcept C110925319 @default.
- W2753867490 hasConcept C119599485 @default.
- W2753867490 hasConcept C121332964 @default.
- W2753867490 hasConcept C121932024 @default.
- W2753867490 hasConcept C12554922 @default.
- W2753867490 hasConcept C127413603 @default.
- W2753867490 hasConcept C158617107 @default.
- W2753867490 hasConcept C180761244 @default.
- W2753867490 hasConcept C181911157 @default.
- W2753867490 hasConcept C185592680 @default.
- W2753867490 hasConcept C26873012 @default.
- W2753867490 hasConcept C41625074 @default.
- W2753867490 hasConcept C55493867 @default.
- W2753867490 hasConcept C59399137 @default.
- W2753867490 hasConcept C60799052 @default.
- W2753867490 hasConcept C62520636 @default.