Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754110156> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2754110156 endingPage "521" @default.
- W2754110156 startingPage "516" @default.
- W2754110156 abstract "Fractionated therapy with 177Lu-DOTATATE has been reported to be an effective treatment for patients with metastasized neuroendocrine tumors. To optimize the treatment, absorbed doses to risk organs are calculated for the individual patient. For each organ, absorbed dose due to activity in the organ itself (self-dose) and that originating from other organs (cross-dose) are calculated from serial measurements to obtain the activity distribution following treatment. The main aim of the present work were to calculate the cross-dose contribution to the total absorbed kidney dose.Five hundred patients with neuroendocrine tumors undergoing therapy with 177Lu-DOTATATE were included. Scintigraphic planar whole body images and single photon emission computed tomography/computed tomography (SPECT/CT) over the abdomen were acquired at 1, 4 and 7 days after treatment. Kidney self-dose was calculated based on radioactivity distribution obtained from SPECT/CT. Cross-dose to kidneys was estimated using organ-based analysis of planar whole body images and cross-fire dose factors from Olinda/EXM 1.1.Cross-dose to kidneys in the majority of patients were less than 2% and almost all cross-doses were less than 10%. Cross-dose exceeded 10% only in rare cases of patients with high tumor burden and low absorbed doses to kidneys.The absorbed dose from 177Lu-octreotate to solid organs due to cross-fire is generally low and can usually be neglected." @default.
- W2754110156 created "2017-09-25" @default.
- W2754110156 creator A5022827045 @default.
- W2754110156 creator A5027523686 @default.
- W2754110156 creator A5032815019 @default.
- W2754110156 creator A5034734088 @default.
- W2754110156 creator A5061260633 @default.
- W2754110156 creator A5090273747 @default.
- W2754110156 date "2017-09-18" @default.
- W2754110156 modified "2023-10-11" @default.
- W2754110156 title "Kidney dosimetry during <sup>177</sup>Lu-DOTATATE therapy in patients with neuroendocrine tumors: aspects on calculation and tolerance" @default.
- W2754110156 cites W1833439679 @default.
- W2754110156 cites W1971384116 @default.
- W2754110156 cites W1983654749 @default.
- W2754110156 cites W1983680048 @default.
- W2754110156 cites W1989552774 @default.
- W2754110156 cites W2000340774 @default.
- W2754110156 cites W2009629472 @default.
- W2754110156 cites W2016237506 @default.
- W2754110156 cites W2017183061 @default.
- W2754110156 cites W2017884723 @default.
- W2754110156 cites W2024035978 @default.
- W2754110156 cites W2027676394 @default.
- W2754110156 cites W2031048655 @default.
- W2754110156 cites W2038146080 @default.
- W2754110156 cites W2047019936 @default.
- W2754110156 cites W2097512974 @default.
- W2754110156 cites W2099478219 @default.
- W2754110156 cites W2108613323 @default.
- W2754110156 cites W2125398839 @default.
- W2754110156 cites W2127498681 @default.
- W2754110156 cites W2142346458 @default.
- W2754110156 cites W2154289925 @default.
- W2754110156 cites W2177207346 @default.
- W2754110156 doi "https://doi.org/10.1080/0284186x.2017.1378431" @default.
- W2754110156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28920501" @default.
- W2754110156 hasPublicationYear "2017" @default.
- W2754110156 type Work @default.
- W2754110156 sameAs 2754110156 @default.
- W2754110156 citedByCount "22" @default.
- W2754110156 countsByYear W27541101562018 @default.
- W2754110156 countsByYear W27541101562019 @default.
- W2754110156 countsByYear W27541101562020 @default.
- W2754110156 countsByYear W27541101562021 @default.
- W2754110156 countsByYear W27541101562022 @default.
- W2754110156 countsByYear W27541101562023 @default.
- W2754110156 crossrefType "journal-article" @default.
- W2754110156 hasAuthorship W2754110156A5022827045 @default.
- W2754110156 hasAuthorship W2754110156A5027523686 @default.
- W2754110156 hasAuthorship W2754110156A5032815019 @default.
- W2754110156 hasAuthorship W2754110156A5034734088 @default.
- W2754110156 hasAuthorship W2754110156A5061260633 @default.
- W2754110156 hasAuthorship W2754110156A5090273747 @default.
- W2754110156 hasBestOaLocation W27541101561 @default.
- W2754110156 hasConcept C126322002 @default.
- W2754110156 hasConcept C126838900 @default.
- W2754110156 hasConcept C149857219 @default.
- W2754110156 hasConcept C151337348 @default.
- W2754110156 hasConcept C2779066768 @default.
- W2754110156 hasConcept C2779983558 @default.
- W2754110156 hasConcept C2780091579 @default.
- W2754110156 hasConcept C2780441642 @default.
- W2754110156 hasConcept C2989005 @default.
- W2754110156 hasConcept C2993559085 @default.
- W2754110156 hasConcept C71924100 @default.
- W2754110156 hasConcept C75088862 @default.
- W2754110156 hasConceptScore W2754110156C126322002 @default.
- W2754110156 hasConceptScore W2754110156C126838900 @default.
- W2754110156 hasConceptScore W2754110156C149857219 @default.
- W2754110156 hasConceptScore W2754110156C151337348 @default.
- W2754110156 hasConceptScore W2754110156C2779066768 @default.
- W2754110156 hasConceptScore W2754110156C2779983558 @default.
- W2754110156 hasConceptScore W2754110156C2780091579 @default.
- W2754110156 hasConceptScore W2754110156C2780441642 @default.
- W2754110156 hasConceptScore W2754110156C2989005 @default.
- W2754110156 hasConceptScore W2754110156C2993559085 @default.
- W2754110156 hasConceptScore W2754110156C71924100 @default.
- W2754110156 hasConceptScore W2754110156C75088862 @default.
- W2754110156 hasIssue "4" @default.
- W2754110156 hasLocation W27541101561 @default.
- W2754110156 hasLocation W27541101562 @default.
- W2754110156 hasOpenAccess W2754110156 @default.
- W2754110156 hasPrimaryLocation W27541101561 @default.
- W2754110156 hasRelatedWork W1833439679 @default.
- W2754110156 hasRelatedWork W1981223719 @default.
- W2754110156 hasRelatedWork W1999397438 @default.
- W2754110156 hasRelatedWork W2017183061 @default.
- W2754110156 hasRelatedWork W2267591082 @default.
- W2754110156 hasRelatedWork W2768013131 @default.
- W2754110156 hasRelatedWork W2900733241 @default.
- W2754110156 hasRelatedWork W3107500641 @default.
- W2754110156 hasRelatedWork W4242130129 @default.
- W2754110156 hasRelatedWork W4255937668 @default.
- W2754110156 hasVolume "57" @default.
- W2754110156 isParatext "false" @default.
- W2754110156 isRetracted "false" @default.
- W2754110156 magId "2754110156" @default.
- W2754110156 workType "article" @default.