Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754322997> ?p ?o ?g. }
- W2754322997 endingPage "271" @default.
- W2754322997 startingPage "245" @default.
- W2754322997 abstract "Natriuretic peptides have received considerable attention in the recent years both as biomarkers for heart failure and as treatment for the disease. Atrial (ANP) and B-type natriuretic peptide (BNP) stimulate the natriuretic peptide receptor (NPR)-A, whereas C-type natriuretic peptide (CNP) stimulates the NPR-B. Both NPR-A and NPR-B are guanylyl cyclases which generate cGMP when stimulated. All three peptides bind the NPR-C which does not possess guanylyl cyclase (GC) activity. Evidence is accumulating that natriuretic peptides are involved in regulating contractility and hypertrophic responses through a complex system of signalling pathways, both cGMP dependent and independent, in different compartments in cardiomyocytes. This review discusses compartmentalisation of natriuretic peptide signalling in cardiomyocytes, with focus on contractile and antihypertrophic effects in healthy and diseased hearts." @default.
- W2754322997 created "2017-09-25" @default.
- W2754322997 creator A5016082073 @default.
- W2754322997 creator A5021485114 @default.
- W2754322997 creator A5042045668 @default.
- W2754322997 creator A5048216612 @default.
- W2754322997 date "2017-01-01" @default.
- W2754322997 modified "2023-09-23" @default.
- W2754322997 title "Compartmentation of Natriuretic Peptide Signalling in Cardiac Myocytes: Effects on Cardiac Contractility and Hypertrophy" @default.
- W2754322997 cites W1491435711 @default.
- W2754322997 cites W1511221661 @default.
- W2754322997 cites W1530911438 @default.
- W2754322997 cites W1531734841 @default.
- W2754322997 cites W1537905458 @default.
- W2754322997 cites W1545935022 @default.
- W2754322997 cites W1553668020 @default.
- W2754322997 cites W1569449226 @default.
- W2754322997 cites W1570238722 @default.
- W2754322997 cites W1584351787 @default.
- W2754322997 cites W1595835172 @default.
- W2754322997 cites W1870846109 @default.
- W2754322997 cites W1948425938 @default.
- W2754322997 cites W1968130104 @default.
- W2754322997 cites W1969046837 @default.
- W2754322997 cites W1969391897 @default.
- W2754322997 cites W1969535241 @default.
- W2754322997 cites W1970184826 @default.
- W2754322997 cites W1972224111 @default.
- W2754322997 cites W1972658664 @default.
- W2754322997 cites W1973872618 @default.
- W2754322997 cites W1981438457 @default.
- W2754322997 cites W1982121289 @default.
- W2754322997 cites W1984732206 @default.
- W2754322997 cites W1985951474 @default.
- W2754322997 cites W1994871589 @default.
- W2754322997 cites W1996140321 @default.
- W2754322997 cites W1998494333 @default.
- W2754322997 cites W2004508563 @default.
- W2754322997 cites W2004795993 @default.
- W2754322997 cites W2007305364 @default.
- W2754322997 cites W2011780678 @default.
- W2754322997 cites W2011920764 @default.
- W2754322997 cites W2012238802 @default.
- W2754322997 cites W2014500068 @default.
- W2754322997 cites W2016975684 @default.
- W2754322997 cites W2017554373 @default.
- W2754322997 cites W2018753286 @default.
- W2754322997 cites W2020159180 @default.
- W2754322997 cites W2020287089 @default.
- W2754322997 cites W2023982165 @default.
- W2754322997 cites W2024105372 @default.
- W2754322997 cites W2025064492 @default.
- W2754322997 cites W2031055455 @default.
- W2754322997 cites W2032341194 @default.
- W2754322997 cites W2033155132 @default.
- W2754322997 cites W2035100090 @default.
- W2754322997 cites W2039165650 @default.
- W2754322997 cites W2043814983 @default.
- W2754322997 cites W2045747999 @default.
- W2754322997 cites W2048990297 @default.
- W2754322997 cites W2052097767 @default.
- W2754322997 cites W2055000625 @default.
- W2754322997 cites W2057937236 @default.
- W2754322997 cites W2058178144 @default.
- W2754322997 cites W2063129749 @default.
- W2754322997 cites W2064466885 @default.
- W2754322997 cites W2064776178 @default.
- W2754322997 cites W2066806344 @default.
- W2754322997 cites W2067021644 @default.
- W2754322997 cites W2069722675 @default.
- W2754322997 cites W2071787882 @default.
- W2754322997 cites W2072214348 @default.
- W2754322997 cites W2072892297 @default.
- W2754322997 cites W2073040810 @default.
- W2754322997 cites W2074388931 @default.
- W2754322997 cites W2074862244 @default.
- W2754322997 cites W2076454764 @default.
- W2754322997 cites W2077969074 @default.
- W2754322997 cites W2082603621 @default.
- W2754322997 cites W2083980443 @default.
- W2754322997 cites W2085011800 @default.
- W2754322997 cites W2085661728 @default.
- W2754322997 cites W2086645400 @default.
- W2754322997 cites W2088190410 @default.
- W2754322997 cites W2088881200 @default.
- W2754322997 cites W2090926515 @default.
- W2754322997 cites W2092312515 @default.
- W2754322997 cites W2093272613 @default.
- W2754322997 cites W2093310120 @default.
- W2754322997 cites W2096716690 @default.
- W2754322997 cites W2097688301 @default.
- W2754322997 cites W2098347291 @default.
- W2754322997 cites W2098548847 @default.
- W2754322997 cites W2098610804 @default.
- W2754322997 cites W2100773246 @default.
- W2754322997 cites W2103751591 @default.
- W2754322997 cites W2105095326 @default.
- W2754322997 cites W2105408675 @default.