Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754384145> ?p ?o ?g. }
- W2754384145 endingPage "592" @default.
- W2754384145 startingPage "578" @default.
- W2754384145 abstract "Rapid progress in the fields of giant cell arteritis and polymyalgia rheumatica has resulted in the introduction of imaging techniques into routine clinical practice and in promising reports on the efficacy of biologic agents for treatment. Further research should further advance our understanding of the epidemiology, pathogenesis, imaging and treatment of these diseases. The fields of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) have advanced rapidly, resulting in a new understanding of these diseases. Fast-track strategies and improved awareness programmes that prevent irreversible sight loss through early diagnosis and treatment are a notable advance. Ultrasonography and other imaging techniques have been introduced into routine clinical practice and there have been promising reports on the efficacy of biologic agents, particularly IL-6 antagonists such as tocilizumab, in treating these conditions. Along with these developments, which should improve outcomes in patients with GCA and PMR, new questions and unmet needs have emerged; future research should address which pathogenetic mechanisms contribute to the different phases and clinical phenotypes of GCA, what role imaging has in the early diagnosis and monitoring of GCA and PMR, and in which patients and phases of these diseases novel biologic drugs should be used. This article discusses the implications of recent developments in our understanding of GCA and PMR, as well as the unmet needs concerning epidemiology, pathogenesis, imaging and treatment of these diseases." @default.
- W2754384145 created "2017-09-25" @default.
- W2754384145 creator A5005994370 @default.
- W2754384145 creator A5011063805 @default.
- W2754384145 creator A5052273654 @default.
- W2754384145 creator A5058094909 @default.
- W2754384145 creator A5062360747 @default.
- W2754384145 creator A5080953929 @default.
- W2754384145 date "2017-09-14" @default.
- W2754384145 modified "2023-10-17" @default.
- W2754384145 title "Giant cell arteritis and polymyalgia rheumatica: current challenges and opportunities" @default.
- W2754384145 cites W116317464 @default.
- W2754384145 cites W1487335409 @default.
- W2754384145 cites W1518484196 @default.
- W2754384145 cites W1521367633 @default.
- W2754384145 cites W1565359762 @default.
- W2754384145 cites W1586194739 @default.
- W2754384145 cites W1654976680 @default.
- W2754384145 cites W1774118966 @default.
- W2754384145 cites W1806117020 @default.
- W2754384145 cites W1908060123 @default.
- W2754384145 cites W1968607662 @default.
- W2754384145 cites W1971675265 @default.
- W2754384145 cites W1974619073 @default.
- W2754384145 cites W1975297209 @default.
- W2754384145 cites W1975835182 @default.
- W2754384145 cites W1978086794 @default.
- W2754384145 cites W1980321521 @default.
- W2754384145 cites W1980820955 @default.
- W2754384145 cites W1983844350 @default.
- W2754384145 cites W1987219056 @default.
- W2754384145 cites W1987316799 @default.
- W2754384145 cites W1989068788 @default.
- W2754384145 cites W1992238153 @default.
- W2754384145 cites W1995278898 @default.
- W2754384145 cites W1998677128 @default.
- W2754384145 cites W1999667015 @default.
- W2754384145 cites W2003810412 @default.
- W2754384145 cites W2012858896 @default.
- W2754384145 cites W2014330392 @default.
- W2754384145 cites W2014570169 @default.
- W2754384145 cites W2015141710 @default.
- W2754384145 cites W2016775906 @default.
- W2754384145 cites W2017295541 @default.
- W2754384145 cites W2022027604 @default.
- W2754384145 cites W2031682782 @default.
- W2754384145 cites W2034454116 @default.
- W2754384145 cites W2041184642 @default.
- W2754384145 cites W2041969183 @default.
- W2754384145 cites W2043657282 @default.
- W2754384145 cites W2043852192 @default.
- W2754384145 cites W2044646622 @default.
- W2754384145 cites W2045925332 @default.
- W2754384145 cites W2047022411 @default.
- W2754384145 cites W2053328369 @default.
- W2754384145 cites W2056768892 @default.
- W2754384145 cites W2057448446 @default.
- W2754384145 cites W2057653070 @default.
- W2754384145 cites W2058952280 @default.
- W2754384145 cites W2062309610 @default.
- W2754384145 cites W2065329061 @default.
- W2754384145 cites W2067965233 @default.
- W2754384145 cites W2071326876 @default.
- W2754384145 cites W2073907836 @default.
- W2754384145 cites W2076498186 @default.
- W2754384145 cites W2077650659 @default.
- W2754384145 cites W2083407120 @default.
- W2754384145 cites W2084214906 @default.
- W2754384145 cites W2086598637 @default.
- W2754384145 cites W2086870793 @default.
- W2754384145 cites W2091058122 @default.
- W2754384145 cites W2093961109 @default.
- W2754384145 cites W2095658145 @default.
- W2754384145 cites W2099377287 @default.
- W2754384145 cites W2100538505 @default.
- W2754384145 cites W2100651899 @default.
- W2754384145 cites W2101211910 @default.
- W2754384145 cites W2101281484 @default.
- W2754384145 cites W2101528090 @default.
- W2754384145 cites W2102149438 @default.
- W2754384145 cites W2111122944 @default.
- W2754384145 cites W2111465526 @default.
- W2754384145 cites W2111894252 @default.
- W2754384145 cites W211424878 @default.
- W2754384145 cites W2115145575 @default.
- W2754384145 cites W2116148601 @default.
- W2754384145 cites W2119733361 @default.
- W2754384145 cites W2119858095 @default.
- W2754384145 cites W2121381593 @default.
- W2754384145 cites W2123496807 @default.
- W2754384145 cites W2124611759 @default.
- W2754384145 cites W2127445888 @default.
- W2754384145 cites W2131663402 @default.
- W2754384145 cites W2132803587 @default.
- W2754384145 cites W2133889834 @default.
- W2754384145 cites W2133915381 @default.
- W2754384145 cites W2135960849 @default.
- W2754384145 cites W2136208734 @default.