FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754425433> ?p ?o ?g. }

• W2754425433 endingPage "365" @default.
• W2754425433 startingPage "355" @default.
• W2754425433 abstract "The great radiation in the infraorder Cyclorrhapha involved several morphological and molecular changes, including important changes in anterior egg development. During Drosophila oogenesis, exuperantia (exu) is critical for localizing bicoid (bcd) messenger RNA (mRNA) to the anterior region of the oocyte. Because it is phylogenetically older than bcd, which is exclusive to Cyclorrhapha, we hypothesize that exu has undergone adaptive changes to enable this new function. Although exu has been well studied in Drosophila, there is no functional or transcriptional information about it in any other Diptera. Here, we investigate exu in the South American fruit fly Anastrepha fraterculus, a Cyclorrhapha of great agricultural importance that have lost bcd, aiming to understand the evolution of exu in this infraorder. We assessed its pattern of gene expression in A. fraterculus by analyzing transcriptomes from cephalic and reproductive tissues. A combination of next-generation data with classical sequencing procedures enabled identification of the structure of exu and its alternative transcripts in this species. In addition to the sex-specific isoforms described for Drosophila, we found that not only exu is expressed in heads, but this is mediated by two transcripts with a specific 5'UTR exon-likely a result from usage of a third promoter. Furthermore, we tested the hypothesis that exu is evolving under positive selection in Cyclorrhapha after divergence from lower Diptera. We found evidence of positive selection at two important exu domains, EXO-like and SAM-like, both involved with mRNA binding during bcd mRNA localization in Drosophila, which could reflect its cooptation for the new function of bcd mRNA localization in Cyclorrhapha." @default.
• W2754425433 created "2017-09-25" @default.
• W2754425433 creator A5003629742 @default.
• W2754425433 creator A5013337867 @default.
• W2754425433 creator A5018753684 @default.
• W2754425433 creator A5050780467 @default.
• W2754425433 date "2017-09-01" @default.
• W2754425433 modified "2023-09-24" @default.
• W2754425433 title "Evolutionary coincidence of adaptive changes in exuperantia and the emergence of bicoid in Cyclorrhapha (Diptera)" @default.
• W2754425433 cites W128773806 @default.
• W2754425433 cites W1571632059 @default.
• W2754425433 cites W1595231518 @default.
• W2754425433 cites W175619361 @default.
• W2754425433 cites W1899988492 @default.
• W2754425433 cites W1964318658 @default.
• W2754425433 cites W1967469883 @default.
• W2754425433 cites W1968224408 @default.
• W2754425433 cites W1969042907 @default.
• W2754425433 cites W1982603712 @default.
• W2754425433 cites W1984261859 @default.
• W2754425433 cites W1987471677 @default.
• W2754425433 cites W1993351732 @default.
• W2754425433 cites W1994760550 @default.
• W2754425433 cites W2003365838 @default.
• W2754425433 cites W2008751779 @default.
• W2754425433 cites W2022397266 @default.
• W2754425433 cites W2025293107 @default.
• W2754425433 cites W2026664850 @default.
• W2754425433 cites W2027180071 @default.
• W2754425433 cites W2028098940 @default.
• W2754425433 cites W2029549914 @default.
• W2754425433 cites W2038813685 @default.
• W2754425433 cites W2050222376 @default.
• W2754425433 cites W2054935441 @default.
• W2754425433 cites W2055043387 @default.
• W2754425433 cites W2056791167 @default.
• W2754425433 cites W2070878566 @default.
• W2754425433 cites W2072718843 @default.
• W2754425433 cites W2082928585 @default.
• W2754425433 cites W2089897307 @default.
• W2754425433 cites W2094671300 @default.
• W2754425433 cites W2097977090 @default.
• W2754425433 cites W2100829140 @default.
• W2754425433 cites W2101353772 @default.
• W2754425433 cites W2103546861 @default.
• W2754425433 cites W2110335151 @default.
• W2754425433 cites W2111211467 @default.
• W2754425433 cites W2112202119 @default.
• W2754425433 cites W2113321565 @default.
• W2754425433 cites W2113644509 @default.
• W2754425433 cites W2116668053 @default.
• W2754425433 cites W2118982822 @default.
• W2754425433 cites W2125867054 @default.
• W2754425433 cites W2126419817 @default.
• W2754425433 cites W2127774996 @default.
• W2754425433 cites W2127981150 @default.
• W2754425433 cites W2140028978 @default.
• W2754425433 cites W2147019339 @default.
• W2754425433 cites W2147191250 @default.
• W2754425433 cites W2147710356 @default.
• W2754425433 cites W2148255658 @default.
• W2754425433 cites W2154845780 @default.
• W2754425433 cites W2156211435 @default.
• W2754425433 cites W2158047579 @default.
• W2754425433 cites W2160714946 @default.
• W2754425433 cites W2161083392 @default.
• W2754425433 cites W2162238964 @default.
• W2754425433 cites W2170565120 @default.
• W2754425433 cites W2173518071 @default.
• W2754425433 cites W2201927605 @default.
• W2754425433 cites W2216863369 @default.
• W2754425433 cites W2464519447 @default.
• W2754425433 cites W2507670212 @default.
• W2754425433 doi "https://doi.org/10.1007/s00427-017-0594-3" @default.
• W2754425433 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5597691" @default.
• W2754425433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28894941" @default.
• W2754425433 hasPublicationYear "2017" @default.
• W2754425433 type Work @default.
• W2754425433 sameAs 2754425433 @default.
• W2754425433 citedByCount "2" @default.
• W2754425433 countsByYear W27544254332018 @default.
• W2754425433 countsByYear W27544254332021 @default.
• W2754425433 crossrefType "journal-article" @default.
• W2754425433 hasAuthorship W2754425433A5003629742 @default.
• W2754425433 hasAuthorship W2754425433A5013337867 @default.
• W2754425433 hasAuthorship W2754425433A5018753684 @default.
• W2754425433 hasAuthorship W2754425433A5050780467 @default.
• W2754425433 hasBestOaLocation W27544254332 @default.
• W2754425433 hasConcept C104317684 @default.
• W2754425433 hasConcept C150194340 @default.
• W2754425433 hasConcept C162317418 @default.
• W2754425433 hasConcept C167290458 @default.
• W2754425433 hasConcept C183074962 @default.
• W2754425433 hasConcept C2776041557 @default.
• W2754425433 hasConcept C2780104201 @default.
• W2754425433 hasConcept C54355233 @default.
• W2754425433 hasConcept C78458016 @default.
• W2754425433 hasConcept C86803240 @default.

• next