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- W2754619391 abstract "We herein report an aqueous synthesis of gelatin stabilized CdTe/CdS/ZnS (CSSG) core/double shell quantum dots (QDs) with improved biocompatibility. The as-synthesized QDs were characterized by ultraviolet-visible (UV–vis) and photoluminescence (PL) spectroscopic techniques, x-ray diffraction technique (XRD), x-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM). The CSSG QDs revealed high photoluminescence quantum yield (PLQY) with excellent stability over a period of one year and retained 90% of its initial PLQY without any aggregation or precipitation under ambient condition. The cell viability study conducted on HeLa, cervical cancer cell lines indicated that the gelatin stabilization effectively decreased the QDs cytotoxicity by about 50%. The CSSG QDs were conjugated with transferrin (Tf) for the efficient delivery to the cancer cells followed by fluorescence imaging. The results showed that the CSSG QDs illuminates the entire cell which renders the QDs as cell labeling markers. The gelatin stabilized core/double shell QDs are potential candidates for long time fluorescent bio-imaging." @default.
- W2754619391 created "2017-09-25" @default.
- W2754619391 creator A5006943962 @default.
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- W2754619391 date "2018-02-01" @default.
- W2754619391 modified "2023-09-27" @default.
- W2754619391 title "Gelatin stabilization of quantum dots for improved stability and biocompatibility" @default.
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- W2754619391 doi "https://doi.org/10.1016/j.ijbiomac.2017.09.039" @default.
- W2754619391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28919525" @default.
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