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- W2754865690 abstract "Background: There have been very few studies on the clinical course of hypertrophic cardiomyopathy (HCM) in a community-based patient cohort in Japan. This time, we focused on types of heart failure (HF) in our unselected registry. Methods and Results: In 2004, we established a cardiomyopathy registration network in Kochi Prefecture, Japan, named Kochi RYOMA study, consisting of 9 hospitals, and finally 293 patients with HCM were followed. The ages at registration and at diagnosis were 63 ± 14 and 56 ± 16 years, respectively. HF events defined as HF deaths and hospitalization for HF, occurred in 35 patients during a mean follow-up period of 6.1 years. Of those patients, 14 patients were due to dilated phase of HCM (D-HCM) defined as left ventricular (LV) systolic dysfunction of ejection fraction <50%. In the remaining 21 patients, 7 patients were associated with LV outflow obstruction, 2 patients had severe mitral regurgitation due to organic abnormality of mitral valve. The other 12 patients were considered to be mainly related to LV diastolic dysfunction. Conclusions: In our unselected registry in an aged Japanese community, HF is an important complication of HCM and 40% of the patients with HF events were associated with D-HCM and 20% were due to LV outflow obstruction. Recognition of the multi-factors evoked to HF is important in HCM." @default.
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- W2754865690 date "2017-10-01" @default.
- W2754865690 modified "2023-09-25" @default.
- W2754865690 title "Different Types of Heart Failure in Hypertrophic Cardiomyopathy in a Community-Based Japanese Cohort: Results From Kochi RYOMA Study" @default.
- W2754865690 doi "https://doi.org/10.1016/j.cardfail.2017.08.358" @default.
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