Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754886464> ?p ?o ?g. }
- W2754886464 endingPage "745" @default.
- W2754886464 startingPage "728" @default.
- W2754886464 abstract "Allergic diseases are common and frequently coexist. Allergen immunotherapy (AIT) is a disease-modifying treatment for IgE-mediated allergic disease with effects beyond cessation of AIT that may include important preventive effects. The European Academy of Allergy and Clinical Immunology (EAACI) has developed a clinical practice guideline to provide evidence-based recommendations for AIT for the prevention of (i) development of allergic comorbidities in those with established allergic diseases, (ii) development of first allergic condition, and (iii) allergic sensitization. This guideline has been developed using the Appraisal of Guidelines for Research & Evaluation (AGREE II) framework, which involved a multidisciplinary expert working group, a systematic review of the underpinning evidence, and external peer-review of draft recommendations. Our key recommendation is that a 3-year course of subcutaneous or sublingual AIT can be recommended for children and adolescents with moderate-to-severe allergic rhinitis (AR) triggered by grass/birch pollen allergy to prevent asthma for up to 2 years post-AIT in addition to its sustained effect on AR symptoms and medication. Some trial data even suggest a preventive effect on asthma symptoms and medication more than 2 years post-AIT. We need more evidence concerning AIT for prevention in individuals with AR triggered by house dust mites or other allergens and for the prevention of allergic sensitization, the first allergic disease, or for the prevention of allergic comorbidities in those with other allergic conditions. Evidence for the preventive potential of AIT as disease-modifying treatment exists but there is an urgent need for more high-quality clinical trials." @default.
- W2754886464 created "2017-09-25" @default.
- W2754886464 creator A5002715841 @default.
- W2754886464 creator A5026215303 @default.
- W2754886464 creator A5026812830 @default.
- W2754886464 creator A5027993808 @default.
- W2754886464 creator A5029886595 @default.
- W2754886464 creator A5030200964 @default.
- W2754886464 creator A5030244193 @default.
- W2754886464 creator A5030907652 @default.
- W2754886464 creator A5032018810 @default.
- W2754886464 creator A5034364156 @default.
- W2754886464 creator A5035034281 @default.
- W2754886464 creator A5035157513 @default.
- W2754886464 creator A5035180962 @default.
- W2754886464 creator A5038251079 @default.
- W2754886464 creator A5040023578 @default.
- W2754886464 creator A5049613521 @default.
- W2754886464 creator A5051198129 @default.
- W2754886464 creator A5054596261 @default.
- W2754886464 creator A5055891096 @default.
- W2754886464 creator A5057548978 @default.
- W2754886464 creator A5058426906 @default.
- W2754886464 creator A5064146791 @default.
- W2754886464 creator A5065281895 @default.
- W2754886464 creator A5069757827 @default.
- W2754886464 creator A5070488224 @default.
- W2754886464 creator A5076448184 @default.
- W2754886464 creator A5083725831 @default.
- W2754886464 creator A5085287314 @default.
- W2754886464 creator A5087343864 @default.
- W2754886464 creator A5091399252 @default.
- W2754886464 date "2017-10-27" @default.
- W2754886464 modified "2023-10-15" @default.
- W2754886464 title "EAACI guidelines on allergen immunotherapy: Prevention of allergy" @default.
- W2754886464 cites W1495964112 @default.
- W2754886464 cites W1515073689 @default.
- W2754886464 cites W1548476693 @default.
- W2754886464 cites W1612985926 @default.
- W2754886464 cites W1875082978 @default.
- W2754886464 cites W1877156325 @default.
- W2754886464 cites W1971098378 @default.
- W2754886464 cites W1973262225 @default.
- W2754886464 cites W1974712839 @default.
- W2754886464 cites W1975510539 @default.
- W2754886464 cites W1977868567 @default.
- W2754886464 cites W1980806499 @default.
- W2754886464 cites W1992719588 @default.
- W2754886464 cites W1995588838 @default.
- W2754886464 cites W1997205735 @default.
- W2754886464 cites W2005115124 @default.
- W2754886464 cites W2010998136 @default.
- W2754886464 cites W2023202501 @default.
- W2754886464 cites W2025143882 @default.
- W2754886464 cites W2025520010 @default.
- W2754886464 cites W2025536251 @default.
- W2754886464 cites W2025695277 @default.
- W2754886464 cites W2027750887 @default.
- W2754886464 cites W2028930921 @default.
- W2754886464 cites W2033232206 @default.
- W2754886464 cites W2038121739 @default.
- W2754886464 cites W2057145918 @default.
- W2754886464 cites W2060328264 @default.
- W2754886464 cites W2062346210 @default.
- W2754886464 cites W2062758156 @default.
- W2754886464 cites W2065738222 @default.
- W2754886464 cites W2072667562 @default.
- W2754886464 cites W2079088504 @default.
- W2754886464 cites W2085196853 @default.
- W2754886464 cites W2086794365 @default.
- W2754886464 cites W2090363075 @default.
- W2754886464 cites W2112333165 @default.
- W2754886464 cites W2124871577 @default.
- W2754886464 cites W2129688566 @default.
- W2754886464 cites W2138363439 @default.
- W2754886464 cites W2140659140 @default.
- W2754886464 cites W2142388937 @default.
- W2754886464 cites W2143397396 @default.
- W2754886464 cites W2150187523 @default.
- W2754886464 cites W2151365195 @default.
- W2754886464 cites W2154126700 @default.
- W2754886464 cites W2154889919 @default.
- W2754886464 cites W2155979288 @default.
- W2754886464 cites W2156787187 @default.
- W2754886464 cites W2164921171 @default.
- W2754886464 cites W2171254450 @default.
- W2754886464 cites W2191648401 @default.
- W2754886464 cites W2272379762 @default.
- W2754886464 cites W2313983825 @default.
- W2754886464 cites W2397222630 @default.
- W2754886464 cites W2462514031 @default.
- W2754886464 cites W2514972674 @default.
- W2754886464 cites W2520815795 @default.
- W2754886464 cites W2521983393 @default.
- W2754886464 cites W2528005888 @default.
- W2754886464 cites W2548351853 @default.
- W2754886464 cites W2730224823 @default.
- W2754886464 cites W2753319752 @default.