Matches in SemOpenAlex for { <https://semopenalex.org/work/W2755202448> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2755202448 abstract "Diabetic nephropathy is the principal single cause of end-stage renal disease. The most important parameter in the clinical evaluation of kidney function is the glomerular filtration rate (GFR), which is generally accepted as the best overall index of kidney function; GFR remains the cornerstone of the clinical evaluation of overall kidney function. Our study was performed to compare between estimated GFR equations based on serum creatinine and/or cystatin C performance in relation to measured GFR using radionuclide study and degree of proteinuria. In our cross-sectional study, 80 adult type 2 diabetic patients, with diabetic nephropathy and proteinuria more than 300 mg/24h, were included after application of inclusion and exclusion criteria, and subjected to history taking, clinical examination, and laboratory investigation including serum creatinine, cystatin C, 24-h urinary protein/creatinine clearance, and renal isotope technetium-99m-diethylene triamine pentaacetic acid scanning. There was a linear correlation between serum creatinine and cystatin C (r=0.867, P=0.000). Cystatin C was better correlated (r=-0.781, P=0.000) with isotopically measured GFR than creatinine (r=-0.106, P=0.348). Cystatin C was better than creatinine in all estimated GFR equations tested in our study [Modification of Diet in Renal Disease, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) Cr 2009, CKD-EPI Cr-Cys2012, CKD-EPI Cys 2012]. Thebest performance among all equations tested when compared with isotopically measured GFR was the CKD-EPI Cr-Cyst 2012 (r=0.816, P=0.000). Cystatin C showed a significant negative correlation with hemoglobin level, a finding that could not be established with serum creatinine; there was no significant association of creatinine or cystatin with the level of proteinuria. In patients with early overt diabetic nephropathy, serum cystatin C showed a significantly stronger correlation than creatinine with isotopically measured GFR, and among the studied equations for GFR estimation the CKD-EPI Cr-Cyst 2012 equation performed best." @default.
- W2755202448 created "2017-09-25" @default.
- W2755202448 creator A5028458390 @default.
- W2755202448 creator A5078347789 @default.
- W2755202448 creator A5083577682 @default.
- W2755202448 date "2017-09-01" @default.
- W2755202448 modified "2023-09-26" @default.
- W2755202448 title "Creatinine, cystatin, and combined-based equations in assessment of renal functions in type 2 diabetic Egyptian patients" @default.
- W2755202448 cites W1974112501 @default.
- W2755202448 cites W1987493257 @default.
- W2755202448 cites W1999056511 @default.
- W2755202448 cites W2003056396 @default.
- W2755202448 cites W2105258594 @default.
- W2755202448 cites W2106932460 @default.
- W2755202448 cites W2107516910 @default.
- W2755202448 cites W2118625269 @default.
- W2755202448 cites W2123655973 @default.
- W2755202448 cites W2123775770 @default.
- W2755202448 cites W2128486308 @default.
- W2755202448 cites W2147165428 @default.
- W2755202448 cites W2155965977 @default.
- W2755202448 cites W2157460296 @default.
- W2755202448 cites W2168905961 @default.
- W2755202448 cites W2169776294 @default.
- W2755202448 cites W2326790784 @default.
- W2755202448 doi "https://doi.org/10.4103/ejim.ejim_26_17" @default.
- W2755202448 hasPublicationYear "2017" @default.
- W2755202448 type Work @default.
- W2755202448 sameAs 2755202448 @default.
- W2755202448 citedByCount "1" @default.
- W2755202448 countsByYear W27552024482021 @default.
- W2755202448 crossrefType "journal-article" @default.
- W2755202448 hasAuthorship W2755202448A5028458390 @default.
- W2755202448 hasAuthorship W2755202448A5078347789 @default.
- W2755202448 hasAuthorship W2755202448A5083577682 @default.
- W2755202448 hasBestOaLocation W27552024481 @default.
- W2755202448 hasConcept C126322002 @default.
- W2755202448 hasConcept C126894567 @default.
- W2755202448 hasConcept C134018914 @default.
- W2755202448 hasConcept C159641895 @default.
- W2755202448 hasConcept C2778653478 @default.
- W2755202448 hasConcept C2779548226 @default.
- W2755202448 hasConcept C2779561371 @default.
- W2755202448 hasConcept C2779922275 @default.
- W2755202448 hasConcept C2780091579 @default.
- W2755202448 hasConcept C2780306776 @default.
- W2755202448 hasConcept C2780412452 @default.
- W2755202448 hasConcept C71924100 @default.
- W2755202448 hasConceptScore W2755202448C126322002 @default.
- W2755202448 hasConceptScore W2755202448C126894567 @default.
- W2755202448 hasConceptScore W2755202448C134018914 @default.
- W2755202448 hasConceptScore W2755202448C159641895 @default.
- W2755202448 hasConceptScore W2755202448C2778653478 @default.
- W2755202448 hasConceptScore W2755202448C2779548226 @default.
- W2755202448 hasConceptScore W2755202448C2779561371 @default.
- W2755202448 hasConceptScore W2755202448C2779922275 @default.
- W2755202448 hasConceptScore W2755202448C2780091579 @default.
- W2755202448 hasConceptScore W2755202448C2780306776 @default.
- W2755202448 hasConceptScore W2755202448C2780412452 @default.
- W2755202448 hasConceptScore W2755202448C71924100 @default.
- W2755202448 hasLocation W27552024481 @default.
- W2755202448 hasOpenAccess W2755202448 @default.
- W2755202448 hasPrimaryLocation W27552024481 @default.
- W2755202448 hasRelatedWork W1984255815 @default.
- W2755202448 hasRelatedWork W1994112911 @default.
- W2755202448 hasRelatedWork W1996136424 @default.
- W2755202448 hasRelatedWork W2003056396 @default.
- W2755202448 hasRelatedWork W2010961667 @default.
- W2755202448 hasRelatedWork W2015143075 @default.
- W2755202448 hasRelatedWork W2088544069 @default.
- W2755202448 hasRelatedWork W2090135940 @default.
- W2755202448 hasRelatedWork W2106809798 @default.
- W2755202448 hasRelatedWork W2414947876 @default.
- W2755202448 hasRelatedWork W2502019889 @default.
- W2755202448 hasRelatedWork W2582790305 @default.
- W2755202448 hasRelatedWork W2591679759 @default.
- W2755202448 hasRelatedWork W2595735708 @default.
- W2755202448 hasRelatedWork W2962337755 @default.
- W2755202448 hasRelatedWork W3010935120 @default.
- W2755202448 hasRelatedWork W3031221918 @default.
- W2755202448 hasRelatedWork W3127888290 @default.
- W2755202448 hasRelatedWork W307339792 @default.
- W2755202448 hasRelatedWork W3104128289 @default.
- W2755202448 isParatext "false" @default.
- W2755202448 isRetracted "false" @default.
- W2755202448 magId "2755202448" @default.
- W2755202448 workType "article" @default.