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- W275525383 abstract "We investigated the effects of the neuroprotective drug cerebrolysin on the autoimmune parameters (FasL, Fas and metallotionein-1) in 20 newborns with perinatal ischemic CNS damage and 20 healthy newborns. The treatment with cerebrolysin in dosage of 0,1 ml per 1 kg of body mass, 10 injections every other day, resulted in the normalization (p<0,001) of the T-lymphocyte apoptosis (the increase of Fas and decrease of FasL) and activation of antioxidant protection through the increase of metallotionein-1 expression. The normalization of the autoimmunity was found to reduce edema and improve the circulation of the brain sites affected with ischemia." @default.
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- W275525383 date "2008-01-01" @default.
- W275525383 modified "2023-09-27" @default.
- W275525383 title "Cerebrolysin alleviates perinatal CNS disorders through the autoimmune modulation and antioxidant protection" @default.
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