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- W2755727310 abstract "Background The benefit of vitamin D on SLE global and renal activity have now been proven by both cohort studies and a clinical trial. The benefits on cardiovascular risk factors, however, are less well understood. Objectives We present the first longitudinal study on hyperlipidemia. Methods A within-person aanalysis addressed the question of whether a person tends to have higher cholesterol when her vitamin D is lower than her average vitamin D. To assess this, for each visit, we calculated the difference between the vitamin D level at that visit and the person9s average of vitamin D. Differences in the range of vitamin D Results This means that at a particular clinic visit, if a person9s vitamin D is higher than the person9s mean vitamin D by 10 ng/mL and the person has vitamin D below 40 ng/mL, then the expected cholesterol will decrease by 3.4 mg/dL. There is no significant effect of higher vitamin D among those whose mean vitamin D exceeds 50. Conclusions Vitamin D supplementation (in those whose level is below 40 ng/mL) has a significant benefit on total cholesterol that is independent of age, sex, ethnicity, Plaquenil, prednisone and body mass index. Vitamin D supplementation - as it also helps systolic blood pressure - is both important for SLE activity and for reduction of cardiovascular disease. Disclosure of Interest None declared" @default.
- W2755727310 created "2017-09-25" @default.
- W2755727310 creator A5082713013 @default.
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- W2755727310 date "2017-06-01" @default.
- W2755727310 modified "2023-09-27" @default.
- W2755727310 title "AB0462 Vitamin d supplementation significantly reduces cholesterol in sle" @default.
- W2755727310 doi "https://doi.org/10.1136/annrheumdis-2017-eular.1647" @default.
- W2755727310 hasPublicationYear "2017" @default.
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