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- W2755982103 abstract "Oxygen is one of the most critical nutrients for all aerobic organisms, especially because most organisms have a very low capacity to carry it. This chapter discusses importance of oxygen as a nutrient and oxygen transfer in cell cultivation. The rate of oxygen transference depends on two other factors: the area that is available for oxygen transfer, and the mass transfer coefficient. The efficiency of mass transfer increases with increasing surface area available for transfer. The oxygen transfer rate (OTR) through an interface is calculated as the multiplicative product of the mass transfer coefficient, the specific transfer area, and the concentration driving force. The chapter presents a few ways to describe the concentration driving force for oxygen transfer. In a bioreactor for cell cultivation, oxygen is typically supplied by blowing air into the culture medium through a sparger. In bioreactors, air sparging is the most common means of supplying oxygen." @default.
- W2755982103 created "2017-09-25" @default.
- W2755982103 creator A5026884944 @default.
- W2755982103 date "2017-09-15" @default.
- W2755982103 modified "2023-10-17" @default.
- W2755982103 title "Oxygen Transfer in Bioreactors" @default.
- W2755982103 doi "https://doi.org/10.1002/9781119159056.ch8" @default.
- W2755982103 hasPublicationYear "2017" @default.
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