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- W2756067852 abstract "A highly selective copper ions fluorescent probe based on the coumarin-type Schiff base derivative 1 (probe) was produced by condensation reaction between coumarin carbohydrazide and 1H-indazole-3-carbaldehyde. The UV–vis spectroscopy showed that the maximum absorption peak of compound 1 appeared at 439 nm. In the presence of Cu2 + ions, the maximum peak decreased remarkably compared with other physiological important metal ions and a new absorption peak at 500 nm appeared. The job's plot experiments showed that complexes of 1:2 binding mode were formed in CH3CN:HEPES (3:2, v/v) solution. Compound 1 exhibited a strong blue fluorescence. Upon addition of copper ions, the fluorescence gradually decreased and reached a plateau with the fluorescence quenching rate up to 98.73%. The detection limit for Cu2 + ions was estimated to 0.384 ppm. Fluorescent microscopy experiments demonstrated that probe 1 had potential to be used to investigate biological processes involving Cu2 + ions within living cells." @default.
- W2756067852 created "2017-09-25" @default.
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- W2756067852 date "2018-02-01" @default.
- W2756067852 modified "2023-10-11" @default.
- W2756067852 title "Synthesis and application of a highly selective copper ions fluorescent probe based on the coumarin group" @default.
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- W2756067852 doi "https://doi.org/10.1016/j.saa.2017.09.028" @default.
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