Matches in SemOpenAlex for { <https://semopenalex.org/work/W2756100732> ?p ?o ?g. }
- W2756100732 abstract "Ultrasonic vocalizations (USVs) are mediated through specific dopaminergic and cholinergic neural pathways and serve as real-time measures of positive and negative emotional status in rodents. Although most USV studies focus primarily on USV counts, each USV possesses a number of characteristics shown to reflect activity in the associated neurotransmitter system. In the present study, we recorded spontaneously emitted USVs from alcohol-naïve high alcohol drinking (HAD-1) and low alcohol drinking (LAD-1) rats. Using our recently developed WAAVES algorithm, we quantified four acoustic characteristics (mean frequency, duration, power, and bandwidth) from each 22-28 kHz and 50-55 kHz frequency-modulated (FM) USV. This rich USV representation allowed us to apply advanced statistical techniques to identify the USV acoustic characteristics that distinguished HAD-1 from LAD-1 rats. Linear mixed models (LMM) examined the predictability of each USV characteristic in isolation and linear discriminant analysis (LDA), and binomial logistic regression examined the predictability of linear combinations of the USV characteristics as a group. Results revealed significant differences in acoustic characteristics between HAD-1 and LAD-1 rats in both 22-28 kHz and 50-55 kHz FM USVs. In other words, these rats selectively bred for high- and low-alcohol consumption can be identified as HAD-1 or LAD-1 rats with high classification accuracy (approximately 92-100%) exclusively based on their emitted 22-28 kHz and 50-55 kHz FM USV acoustic characteristics. In addition, acoustic characteristics of 22-28 kHz and 50-55 kHz FM USVs emitted by alcohol-naïve HAD-1 and LAD-1 rats significantly correlate with their future alcohol consumption. Our current findings provide novel evidence that USV acoustic characteristics can be used to discriminate between alcohol-naïve HAD-1 and LAD-1 rats, and may serve as biomarkers in rodents with a predisposition for, or against, excessive alcohol intake." @default.
- W2756100732 created "2017-09-25" @default.
- W2756100732 creator A5020669661 @default.
- W2756100732 creator A5032781961 @default.
- W2756100732 creator A5049840520 @default.
- W2756100732 creator A5070595162 @default.
- W2756100732 creator A5080273132 @default.
- W2756100732 creator A5080937269 @default.
- W2756100732 creator A5087782377 @default.
- W2756100732 date "2018-05-01" @default.
- W2756100732 modified "2023-10-15" @default.
- W2756100732 title "Alcohol-naïve USVs distinguish male HAD-1 from LAD-1 rat strains" @default.
- W2756100732 cites W1023607167 @default.
- W2756100732 cites W1972318409 @default.
- W2756100732 cites W1974943902 @default.
- W2756100732 cites W1986206654 @default.
- W2756100732 cites W1995702730 @default.
- W2756100732 cites W1997881752 @default.
- W2756100732 cites W2013032254 @default.
- W2756100732 cites W2013683788 @default.
- W2756100732 cites W2016994260 @default.
- W2756100732 cites W2024051599 @default.
- W2756100732 cites W2033560214 @default.
- W2756100732 cites W2034728437 @default.
- W2756100732 cites W2037393837 @default.
- W2756100732 cites W2038942915 @default.
- W2756100732 cites W2039618998 @default.
- W2756100732 cites W2049733279 @default.
- W2756100732 cites W2053046056 @default.
- W2756100732 cites W2057734967 @default.
- W2756100732 cites W2065648602 @default.
- W2756100732 cites W2068719023 @default.
- W2756100732 cites W2077863458 @default.
- W2756100732 cites W2078340404 @default.
- W2756100732 cites W2078716429 @default.
- W2756100732 cites W2087080450 @default.
- W2756100732 cites W2093730749 @default.
- W2756100732 cites W2125859211 @default.
- W2756100732 cites W2128406566 @default.
- W2756100732 cites W2128849538 @default.
- W2756100732 cites W2128864608 @default.
- W2756100732 cites W2134945999 @default.
- W2756100732 cites W2146685566 @default.
- W2756100732 cites W2157759655 @default.
- W2756100732 cites W2179737758 @default.
- W2756100732 cites W2221261812 @default.
- W2756100732 cites W2275703686 @default.
- W2756100732 cites W2284657754 @default.
- W2756100732 cites W2287238275 @default.
- W2756100732 cites W2397857871 @default.
- W2756100732 cites W2418056822 @default.
- W2756100732 cites W2460239665 @default.
- W2756100732 cites W2465817884 @default.
- W2756100732 cites W2491859250 @default.
- W2756100732 cites W2553183677 @default.
- W2756100732 cites W2575945055 @default.
- W2756100732 cites W2582499615 @default.
- W2756100732 cites W2774486220 @default.
- W2756100732 cites W4236777406 @default.
- W2756100732 cites W4377237676 @default.
- W2756100732 doi "https://doi.org/10.1016/j.alcohol.2017.09.003" @default.
- W2756100732 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5851795" @default.
- W2756100732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29427829" @default.
- W2756100732 hasPublicationYear "2018" @default.
- W2756100732 type Work @default.
- W2756100732 sameAs 2756100732 @default.
- W2756100732 citedByCount "6" @default.
- W2756100732 countsByYear W27561007322017 @default.
- W2756100732 countsByYear W27561007322019 @default.
- W2756100732 countsByYear W27561007322020 @default.
- W2756100732 countsByYear W27561007322021 @default.
- W2756100732 crossrefType "journal-article" @default.
- W2756100732 hasAuthorship W2756100732A5020669661 @default.
- W2756100732 hasAuthorship W2756100732A5032781961 @default.
- W2756100732 hasAuthorship W2756100732A5049840520 @default.
- W2756100732 hasAuthorship W2756100732A5070595162 @default.
- W2756100732 hasAuthorship W2756100732A5080273132 @default.
- W2756100732 hasAuthorship W2756100732A5080937269 @default.
- W2756100732 hasAuthorship W2756100732A5087782377 @default.
- W2756100732 hasBestOaLocation W27561007321 @default.
- W2756100732 hasConcept C126322002 @default.
- W2756100732 hasConcept C2781066024 @default.
- W2756100732 hasConcept C3019635848 @default.
- W2756100732 hasConcept C548259974 @default.
- W2756100732 hasConcept C55493867 @default.
- W2756100732 hasConcept C71924100 @default.
- W2756100732 hasConcept C86803240 @default.
- W2756100732 hasConceptScore W2756100732C126322002 @default.
- W2756100732 hasConceptScore W2756100732C2781066024 @default.
- W2756100732 hasConceptScore W2756100732C3019635848 @default.
- W2756100732 hasConceptScore W2756100732C548259974 @default.
- W2756100732 hasConceptScore W2756100732C55493867 @default.
- W2756100732 hasConceptScore W2756100732C71924100 @default.
- W2756100732 hasConceptScore W2756100732C86803240 @default.
- W2756100732 hasLocation W27561007321 @default.
- W2756100732 hasLocation W27561007322 @default.
- W2756100732 hasLocation W27561007323 @default.
- W2756100732 hasLocation W27561007324 @default.
- W2756100732 hasLocation W27561007325 @default.
- W2756100732 hasOpenAccess W2756100732 @default.