Matches in SemOpenAlex for { <https://semopenalex.org/work/W2756153529> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2756153529 endingPage "33" @default.
- W2756153529 startingPage "24" @default.
- W2756153529 abstract "Abstract The aim of this study was to develop micro- or macro-porous substrates of poly(L-lactic acid) (PLLA) for the sustained release of water-soluble proteins. A model protein, bovine serum albumin (BSA), was incorporated into the hydrophobous PLLA matrix by emulsifying an aqueous BSA solution into an organic PLLA solution. The work focused on the effect of the fabrication procedure on substrates' microstructure and protein delivery kinetics. The films were prepared by solvent casting or freeze-extraction, after which the protein release profiles from both matrices were compared. A homogeneous distribution of BSA in the PLLA-films and membranes was obtained. In vitro release of the protein from the freeze-extraction membranes was more significant than the release from the solvent cast films. BSA was found to be released from the freeze-extraction membranes in two stages: an initial fast release followed by a sustained release. The release from the solvent cast films was more moderated and accompanied by the polymer degradation. These materials can find applications in wound healing by local delivery of proteins known to have a positive effect on the regeneration of basal lamina. They can also be used to produce macroporous scaffolds able to deliver growth factors during bone or cartilage regeneration." @default.
- W2756153529 created "2017-09-25" @default.
- W2756153529 creator A5040167678 @default.
- W2756153529 creator A5047383841 @default.
- W2756153529 creator A5061951701 @default.
- W2756153529 creator A5083680222 @default.
- W2756153529 date "2017-12-01" @default.
- W2756153529 modified "2023-09-24" @default.
- W2756153529 title "Emulsion based microencapsulation of proteins in poly(L-lactic acid) films and membranes for the controlled release of drugs" @default.
- W2756153529 cites W1964051507 @default.
- W2756153529 cites W1968088053 @default.
- W2756153529 cites W1968518371 @default.
- W2756153529 cites W1989879890 @default.
- W2756153529 cites W2009492770 @default.
- W2756153529 cites W2010446759 @default.
- W2756153529 cites W2014611041 @default.
- W2756153529 cites W2019717996 @default.
- W2756153529 cites W2043812085 @default.
- W2756153529 cites W2051428460 @default.
- W2756153529 cites W2063579545 @default.
- W2756153529 cites W2070029492 @default.
- W2756153529 cites W2073598879 @default.
- W2756153529 cites W2087800771 @default.
- W2756153529 cites W2097411724 @default.
- W2756153529 cites W2099572386 @default.
- W2756153529 cites W2141965713 @default.
- W2756153529 cites W2145023819 @default.
- W2756153529 cites W2165571895 @default.
- W2756153529 cites W2257946332 @default.
- W2756153529 cites W2279223249 @default.
- W2756153529 cites W2288927818 @default.
- W2756153529 cites W2294239686 @default.
- W2756153529 cites W2312627459 @default.
- W2756153529 cites W2316460535 @default.
- W2756153529 cites W2333157808 @default.
- W2756153529 cites W4251960546 @default.
- W2756153529 doi "https://doi.org/10.1016/j.polymdegradstab.2017.09.012" @default.
- W2756153529 hasPublicationYear "2017" @default.
- W2756153529 type Work @default.
- W2756153529 sameAs 2756153529 @default.
- W2756153529 citedByCount "5" @default.
- W2756153529 countsByYear W27561535292019 @default.
- W2756153529 countsByYear W27561535292020 @default.
- W2756153529 countsByYear W27561535292021 @default.
- W2756153529 crossrefType "journal-article" @default.
- W2756153529 hasAuthorship W2756153529A5040167678 @default.
- W2756153529 hasAuthorship W2756153529A5047383841 @default.
- W2756153529 hasAuthorship W2756153529A5061951701 @default.
- W2756153529 hasAuthorship W2756153529A5083680222 @default.
- W2756153529 hasConcept C126348684 @default.
- W2756153529 hasConcept C127413603 @default.
- W2756153529 hasConcept C178790620 @default.
- W2756153529 hasConcept C185592680 @default.
- W2756153529 hasConcept C188027245 @default.
- W2756153529 hasConcept C192562407 @default.
- W2756153529 hasConcept C2775920511 @default.
- W2756153529 hasConcept C2778123984 @default.
- W2756153529 hasConcept C41625074 @default.
- W2756153529 hasConcept C42360764 @default.
- W2756153529 hasConcept C523546767 @default.
- W2756153529 hasConcept C54355233 @default.
- W2756153529 hasConcept C55493867 @default.
- W2756153529 hasConcept C86803240 @default.
- W2756153529 hasConceptScore W2756153529C126348684 @default.
- W2756153529 hasConceptScore W2756153529C127413603 @default.
- W2756153529 hasConceptScore W2756153529C178790620 @default.
- W2756153529 hasConceptScore W2756153529C185592680 @default.
- W2756153529 hasConceptScore W2756153529C188027245 @default.
- W2756153529 hasConceptScore W2756153529C192562407 @default.
- W2756153529 hasConceptScore W2756153529C2775920511 @default.
- W2756153529 hasConceptScore W2756153529C2778123984 @default.
- W2756153529 hasConceptScore W2756153529C41625074 @default.
- W2756153529 hasConceptScore W2756153529C42360764 @default.
- W2756153529 hasConceptScore W2756153529C523546767 @default.
- W2756153529 hasConceptScore W2756153529C54355233 @default.
- W2756153529 hasConceptScore W2756153529C55493867 @default.
- W2756153529 hasConceptScore W2756153529C86803240 @default.
- W2756153529 hasFunder F4320334923 @default.
- W2756153529 hasFunder F4320335322 @default.
- W2756153529 hasLocation W27561535291 @default.
- W2756153529 hasOpenAccess W2756153529 @default.
- W2756153529 hasPrimaryLocation W27561535291 @default.
- W2756153529 hasRelatedWork W2013389144 @default.
- W2756153529 hasRelatedWork W2033391218 @default.
- W2756153529 hasRelatedWork W2777720552 @default.
- W2756153529 hasRelatedWork W2990101235 @default.
- W2756153529 hasRelatedWork W3020193469 @default.
- W2756153529 hasRelatedWork W3035401649 @default.
- W2756153529 hasRelatedWork W4283742444 @default.
- W2756153529 hasRelatedWork W4310750409 @default.
- W2756153529 hasRelatedWork W4313824467 @default.
- W2756153529 hasRelatedWork W4315619474 @default.
- W2756153529 hasVolume "146" @default.
- W2756153529 isParatext "false" @default.
- W2756153529 isRetracted "false" @default.
- W2756153529 magId "2756153529" @default.
- W2756153529 workType "article" @default.