Matches in SemOpenAlex for { <https://semopenalex.org/work/W2756281098> ?p ?o ?g. }
- W2756281098 abstract "Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency are at risk of severe haemolysis following the administration of 8-aminoquinoline compounds. Primaquine is the only widely available 8-aminoquinoline for the radical cure of Plasmodium vivax. Tafenoquine is under development with the potential to simplify treatment regimens, but point-of-care (PoC) tests will be needed to provide quantitative measurement of G6PD activity prior to its administration. There is currently a lack of appropriate G6PD PoC tests, but a number of new tests are in development and are likely to enter the market in the coming years. As these are implemented, they will need to be validated in field studies. This article outlines the technical details for the field evaluation of novel quantitative G6PD diagnostics such as sample handling, reference testing and statistical analysis. Field evaluation is based on the comparison of paired samples, including one sample tested by the new assay at point of care and one sample tested by the gold-standard reference method, UV spectrophotometry in an established laboratory. Samples can be collected as capillary or venous blood; the existing literature suggests that potential differences in capillary or venous blood are unlikely to affect results substantially. The collection and storage of samples is critical to ensure preservation of enzyme activity, it is recommended that samples are stored at 4 °C and testing occurs within 4 days of collection. Test results can be visually presented as scatter plot, Bland-Altman plot, and a histogram of the G6PD activity distribution of the study population. Calculating the adjusted male median allows categorizing results according to G6PD activity to calculate standard performance indicators and to perform receiver operating characteristic (ROC) analysis." @default.
- W2756281098 created "2017-09-25" @default.
- W2756281098 creator A5004484860 @default.
- W2756281098 creator A5019034894 @default.
- W2756281098 creator A5029292055 @default.
- W2756281098 creator A5048285768 @default.
- W2756281098 creator A5050939729 @default.
- W2756281098 creator A5075552954 @default.
- W2756281098 creator A5091743305 @default.
- W2756281098 date "2017-09-11" @default.
- W2756281098 modified "2023-10-14" @default.
- W2756281098 title "Methods for the field evaluation of quantitative G6PD diagnostics: a review" @default.
- W2756281098 cites W1491184535 @default.
- W2756281098 cites W1494052777 @default.
- W2756281098 cites W1572077412 @default.
- W2756281098 cites W1965872090 @default.
- W2756281098 cites W1997182468 @default.
- W2756281098 cites W2015795623 @default.
- W2756281098 cites W2016066083 @default.
- W2756281098 cites W2020296173 @default.
- W2756281098 cites W2038084338 @default.
- W2756281098 cites W2052568053 @default.
- W2756281098 cites W2053138534 @default.
- W2756281098 cites W2064306519 @default.
- W2756281098 cites W2082525341 @default.
- W2756281098 cites W2087711878 @default.
- W2756281098 cites W2088888368 @default.
- W2756281098 cites W2103147419 @default.
- W2756281098 cites W2104946694 @default.
- W2756281098 cites W2107453477 @default.
- W2756281098 cites W2110552450 @default.
- W2756281098 cites W2112999303 @default.
- W2756281098 cites W2116590229 @default.
- W2756281098 cites W2117767554 @default.
- W2756281098 cites W2127073450 @default.
- W2756281098 cites W2129838040 @default.
- W2756281098 cites W2133140374 @default.
- W2756281098 cites W2136086474 @default.
- W2756281098 cites W2144016867 @default.
- W2756281098 cites W2154179758 @default.
- W2756281098 cites W2154397011 @default.
- W2756281098 cites W2158266463 @default.
- W2756281098 cites W2161252729 @default.
- W2756281098 cites W2164581339 @default.
- W2756281098 cites W2165752279 @default.
- W2756281098 cites W2181406325 @default.
- W2756281098 cites W2228811009 @default.
- W2756281098 cites W2261982693 @default.
- W2756281098 cites W2284987684 @default.
- W2756281098 cites W2328977475 @default.
- W2756281098 cites W2329953645 @default.
- W2756281098 cites W2418660282 @default.
- W2756281098 cites W2507296118 @default.
- W2756281098 cites W2508919424 @default.
- W2756281098 cites W2539685726 @default.
- W2756281098 cites W2582844219 @default.
- W2756281098 cites W2604837458 @default.
- W2756281098 cites W2749887661 @default.
- W2756281098 cites W4235948172 @default.
- W2756281098 cites W4298337257 @default.
- W2756281098 cites W4300670732 @default.
- W2756281098 doi "https://doi.org/10.1186/s12936-017-2017-3" @default.
- W2756281098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5594530" @default.
- W2756281098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28893237" @default.
- W2756281098 hasPublicationYear "2017" @default.
- W2756281098 type Work @default.
- W2756281098 sameAs 2756281098 @default.
- W2756281098 citedByCount "39" @default.
- W2756281098 countsByYear W27562810982018 @default.
- W2756281098 countsByYear W27562810982019 @default.
- W2756281098 countsByYear W27562810982020 @default.
- W2756281098 countsByYear W27562810982021 @default.
- W2756281098 countsByYear W27562810982022 @default.
- W2756281098 countsByYear W27562810982023 @default.
- W2756281098 crossrefType "journal-article" @default.
- W2756281098 hasAuthorship W2756281098A5004484860 @default.
- W2756281098 hasAuthorship W2756281098A5019034894 @default.
- W2756281098 hasAuthorship W2756281098A5029292055 @default.
- W2756281098 hasAuthorship W2756281098A5048285768 @default.
- W2756281098 hasAuthorship W2756281098A5050939729 @default.
- W2756281098 hasAuthorship W2756281098A5075552954 @default.
- W2756281098 hasAuthorship W2756281098A5091743305 @default.
- W2756281098 hasBestOaLocation W27562810981 @default.
- W2756281098 hasConcept C105795698 @default.
- W2756281098 hasConcept C126322002 @default.
- W2756281098 hasConcept C134018914 @default.
- W2756281098 hasConcept C142724271 @default.
- W2756281098 hasConcept C185592680 @default.
- W2756281098 hasConcept C19527891 @default.
- W2756281098 hasConcept C198531522 @default.
- W2756281098 hasConcept C203014093 @default.
- W2756281098 hasConcept C2776793103 @default.
- W2756281098 hasConcept C2777425658 @default.
- W2756281098 hasConcept C2777580121 @default.
- W2756281098 hasConcept C2778048844 @default.
- W2756281098 hasConcept C2908647359 @default.
- W2756281098 hasConcept C2910801743 @default.
- W2756281098 hasConcept C3018890749 @default.
- W2756281098 hasConcept C33070731 @default.
- W2756281098 hasConcept C33923547 @default.