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- W2756475796 abstract "We took advantage of gasotransmitter H2S as a chemical reaction-based trigger for controlled release of doxorubicin which is precoordinated by copper ions and enclosed in horse spleen apoferritin. The nanocomposite is stable at physiological pH and temperature before H2S activation. The drug release process avoids disassembly of protein shells and is controllable by the strong affinity of sulfide with copper ions. The in vitro cytotoxicity assay indicates the antitumor effect of doxorubicin toward tumor cells could be achievable by H2S activation." @default.
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- W2756475796 date "2017-09-19" @default.
- W2756475796 modified "2023-09-27" @default.
- W2756475796 title "H<sub>2</sub>S Activated Drug Release from Protein Cages" @default.
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- W2756475796 doi "https://doi.org/10.1021/acsami.7b12524" @default.
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