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- W2756543990 abstract "Beside a proven antimicrobial and inflammatory-modulating spectrum of plasma therapy, recent studies point to impressive molecular and cellular effects against tumor cells. However, underlying mechanisms of anticancer effects and improved wound healing, in particular plasma associated influence on microcirculation, have not been sufficiently clarified yet. To date, there is no convincing method for monitoring therapy with cold atmospheric plasma (CAP) in vivo. After cold plasma treatment with kINPen MED a hyperspectral analysis with the TIVITA™ Tissue System (Diaspective Vision, Pepelow, Germany) was performed in two different patient cases. TIVITA™ Tissue System is an innovative hybrid technology that combines imaging and spectroscopy for assessment and documentation of tissue. HSI was able to demonstrate CAP associated effects on microcirculation showing a relevant increase of superficial and deeper cutaneous oxygen saturation, hemoglobin concentration and distribution. HSI was able to demonstrate CAP-associated effects on microcirculation showing a relevant increase in superficial and deeper skin oxygen saturation, haemoglobin concentration and distribution. As a clinical diagnostic tool, hyperspectral imaging thus provides further information for a better understanding of microcirculatory CAP effects in cancer therapy and wound healing processes." @default.
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- W2756543990 date "2017-12-01" @default.
- W2756543990 modified "2023-10-12" @default.
- W2756543990 title "Hyperspectral imaging for in vivo monitoring of cold atmospheric plasma effects on microcirculation in treatment of head and neck cancer and wound healing" @default.
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- W2756543990 doi "https://doi.org/10.1016/j.cpme.2017.09.002" @default.
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