Matches in SemOpenAlex for { <https://semopenalex.org/work/W2757000254> ?p ?o ?g. }
- W2757000254 endingPage "12066" @default.
- W2757000254 startingPage "12054" @default.
- W2757000254 abstract "An engineered metallic nanostructure is an excellent candidate for theranosis of cancer, having intrinsic properties of multimodal imaging and therapy. Toward this target, the development of silver-neodymium bimetallic nanoparticles (Ag-Nd BNPs) via microwave-assisted polyol synthesis is presented. The resultant Ag-Nd BNPs exhibit good monodispersity with average size of 10 nm, fluorescence in the near-infrared (NIR) region, and magnetic properties. The Ag-Nd BNPs also validate MRI, CT, and NIR trimodal imaging ability and enunciate valuable temperature response upon irradiation under a NIR laser. Aided by chitosan functionalization on the surface, the Ag-Nd BNPs deliver good biocompatibility and also promote the loading of paclitaxel, an anticancer drug. Isothermal titration calorimetry affirms the combination of strong binding affinity of drug and high loading efficiency of 7 drug molecules per nanoparticle. Moreover, Ag-Nd BNPs also illustrate a highly efficient photothermal effect in PBS. Therefore, the synergistic effects of paclitaxel and the photothermal effect make BNPs excellent combined therapeutic agents, and also give them the important ability to destroy cancer cells in vitro at very low dose in comparison to single therapy. Thus, the Ag-Nd BNPs unveil a combination of MRI/CT/NIR imaging and chemo-photothermal therapy that ensures accurate diagnosis at an early stage and comprehensive eradication of tumor cells without affecting healthy cells." @default.
- W2757000254 created "2017-10-06" @default.
- W2757000254 creator A5042964770 @default.
- W2757000254 creator A5059589515 @default.
- W2757000254 date "2017-09-21" @default.
- W2757000254 modified "2023-10-12" @default.
- W2757000254 title "A Bimetallic Silver–Neodymium Theranostic Nanoparticle with Multimodal NIR/MRI/CT Imaging and Combined Chemo-photothermal Therapy" @default.
- W2757000254 cites W1837084752 @default.
- W2757000254 cites W1859613743 @default.
- W2757000254 cites W1967645047 @default.
- W2757000254 cites W1967678184 @default.
- W2757000254 cites W1984364596 @default.
- W2757000254 cites W1985105201 @default.
- W2757000254 cites W1997924525 @default.
- W2757000254 cites W2002921622 @default.
- W2757000254 cites W2006687439 @default.
- W2757000254 cites W2011186375 @default.
- W2757000254 cites W2012777785 @default.
- W2757000254 cites W2017266185 @default.
- W2757000254 cites W2017456485 @default.
- W2757000254 cites W2018307798 @default.
- W2757000254 cites W2022209864 @default.
- W2757000254 cites W2028744130 @default.
- W2757000254 cites W2035855761 @default.
- W2757000254 cites W2039260558 @default.
- W2757000254 cites W2041671919 @default.
- W2757000254 cites W2043939902 @default.
- W2757000254 cites W2044125214 @default.
- W2757000254 cites W2046132696 @default.
- W2757000254 cites W2052973806 @default.
- W2757000254 cites W2058457363 @default.
- W2757000254 cites W2061446026 @default.
- W2757000254 cites W2066254002 @default.
- W2757000254 cites W2073301678 @default.
- W2757000254 cites W2074744511 @default.
- W2757000254 cites W2074816429 @default.
- W2757000254 cites W2076690149 @default.
- W2757000254 cites W2086158052 @default.
- W2757000254 cites W2088075975 @default.
- W2757000254 cites W2089613422 @default.
- W2757000254 cites W2096157569 @default.
- W2757000254 cites W2112205420 @default.
- W2757000254 cites W2121576598 @default.
- W2757000254 cites W2134353889 @default.
- W2757000254 cites W2138625819 @default.
- W2757000254 cites W2144324113 @default.
- W2757000254 cites W2145699985 @default.
- W2757000254 cites W2155465461 @default.
- W2757000254 cites W2161914936 @default.
- W2757000254 cites W2170824662 @default.
- W2757000254 cites W2256119932 @default.
- W2757000254 cites W2273413083 @default.
- W2757000254 cites W2289358753 @default.
- W2757000254 cites W2293545604 @default.
- W2757000254 cites W2312528880 @default.
- W2757000254 cites W2315665240 @default.
- W2757000254 cites W2321481829 @default.
- W2757000254 cites W2322129584 @default.
- W2757000254 cites W2327315751 @default.
- W2757000254 cites W2327341564 @default.
- W2757000254 cites W2404759276 @default.
- W2757000254 cites W2414123584 @default.
- W2757000254 cites W2468538105 @default.
- W2757000254 cites W2475831462 @default.
- W2757000254 cites W2507547566 @default.
- W2757000254 cites W2513844403 @default.
- W2757000254 cites W2526079712 @default.
- W2757000254 cites W2530865780 @default.
- W2757000254 cites W2556407097 @default.
- W2757000254 cites W2562434823 @default.
- W2757000254 cites W2567270793 @default.
- W2757000254 cites W2581991848 @default.
- W2757000254 cites W4247140791 @default.
- W2757000254 cites W4237906573 @default.
- W2757000254 doi "https://doi.org/10.1021/acs.inorgchem.7b02103" @default.
- W2757000254 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28933536" @default.
- W2757000254 hasPublicationYear "2017" @default.
- W2757000254 type Work @default.
- W2757000254 sameAs 2757000254 @default.
- W2757000254 citedByCount "33" @default.
- W2757000254 countsByYear W27570002542017 @default.
- W2757000254 countsByYear W27570002542018 @default.
- W2757000254 countsByYear W27570002542019 @default.
- W2757000254 countsByYear W27570002542020 @default.
- W2757000254 countsByYear W27570002542021 @default.
- W2757000254 countsByYear W27570002542022 @default.
- W2757000254 countsByYear W27570002542023 @default.
- W2757000254 crossrefType "journal-article" @default.
- W2757000254 hasAuthorship W2757000254A5042964770 @default.
- W2757000254 hasAuthorship W2757000254A5059589515 @default.
- W2757000254 hasConcept C115537861 @default.
- W2757000254 hasConcept C147789679 @default.
- W2757000254 hasConcept C155672457 @default.
- W2757000254 hasConcept C171250308 @default.
- W2757000254 hasConcept C178790620 @default.
- W2757000254 hasConcept C182606246 @default.
- W2757000254 hasConcept C185592680 @default.
- W2757000254 hasConcept C192562407 @default.