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• W2757005118 abstract "Since the first experimental hint for the existence of “an actual desire or striving for the drug” in nonhuman animals by Sidney Spragg in the late 1930s, much effort has been expended by lab researchers to try to model in a valid manner the key behavioral aspects and signs of addiction in animals, typically in rodents (i.e., mainly rats and, to a lesser extent, mice). Despite much advances, there still remains a lingering doubt about the disordered status of drug use in rodents. This is mainly because drug use occurs in a particular setting where animals have access to a drug for self-administration but without access to other valuable behavioral options that could compete with and divert from drug use. Here I review evidence showing that enriching the drug setting with other behavioral options can dramatically influence the pattern of drug choices in rodents. Overall, access to other options during drug access can divert the vast majority of rats from continued drug use. Only few individuals continue to engage in drug use despite access to and at the expense of other options. However, there exist certain high-risk settings in which virtually all animals are vulnerable to develop a harmful pattern of exclusive drug use that can even become fatal in the long run if not discontinued by an outside intervention. Paradoxically, it appears that the behavioral trait that is hypothesized to uniquely render rodents vulnerable to the latter settings (i.e., a narrow focus on the local, current choice, with no consideration of the global pattern of choice) would also protect most of them from using drugs in other choice settings. I conclude with an attempt to make sense of this peculiar setting-specific behavior and with some general propositions for future research." @default.
• W2757005118 created "2017-10-06" @default.
• W2757005118 creator A5047946147 @default.
• W2757005118 date "2018-12-01" @default.
• W2757005118 modified "2023-10-09" @default.
• W2757005118 title "Trying to make sense of rodents' drug choice behavior" @default.
• W2757005118 cites W1571530925 @default.
• W2757005118 cites W1584054336 @default.
• W2757005118 cites W1823260965 @default.
• W2757005118 cites W1898180549 @default.
• W2757005118 cites W1912972409 @default.
• W2757005118 cites W1941428045 @default.
• W2757005118 cites W1943481740 @default.
• W2757005118 cites W1948666820 @default.
• W2757005118 cites W1965927079 @default.
• W2757005118 cites W1970238016 @default.
• W2757005118 cites W1981101811 @default.
• W2757005118 cites W1981372632 @default.
• W2757005118 cites W1982311927 @default.
• W2757005118 cites W1984024293 @default.
• W2757005118 cites W1984045082 @default.
• W2757005118 cites W1984727326 @default.
• W2757005118 cites W1986287138 @default.
• W2757005118 cites W1986911450 @default.
• W2757005118 cites W1988182239 @default.
• W2757005118 cites W1994077204 @default.
• W2757005118 cites W1994285916 @default.
• W2757005118 cites W2000409926 @default.
• W2757005118 cites W2005092824 @default.
• W2757005118 cites W2005604072 @default.
• W2757005118 cites W2005921391 @default.
• W2757005118 cites W2010185204 @default.
• W2757005118 cites W2013536737 @default.
• W2757005118 cites W2017133033 @default.
• W2757005118 cites W2019686965 @default.
• W2757005118 cites W2020320083 @default.
• W2757005118 cites W2021055249 @default.
• W2757005118 cites W2021576621 @default.
• W2757005118 cites W2022691480 @default.
• W2757005118 cites W2024621487 @default.
• W2757005118 cites W2027931582 @default.
• W2757005118 cites W2030255787 @default.
• W2757005118 cites W2039389383 @default.
• W2757005118 cites W2040903782 @default.
• W2757005118 cites W2043150207 @default.
• W2757005118 cites W2043476737 @default.
• W2757005118 cites W2053414348 @default.
• W2757005118 cites W2055084871 @default.
• W2757005118 cites W2063553039 @default.
• W2757005118 cites W2063933554 @default.
• W2757005118 cites W2064184606 @default.
• W2757005118 cites W2065485036 @default.
• W2757005118 cites W2066926223 @default.
• W2757005118 cites W2077624548 @default.
• W2757005118 cites W2078716429 @default.
• W2757005118 cites W2079656841 @default.
• W2757005118 cites W2080895561 @default.
• W2757005118 cites W2082529291 @default.
• W2757005118 cites W2086313373 @default.
• W2757005118 cites W2087657646 @default.
• W2757005118 cites W2094928962 @default.
• W2757005118 cites W2101674265 @default.
• W2757005118 cites W2107606334 @default.
• W2757005118 cites W2109944937 @default.
• W2757005118 cites W2112323466 @default.
• W2757005118 cites W2112643649 @default.
• W2757005118 cites W2117002154 @default.
• W2757005118 cites W2118363256 @default.
• W2757005118 cites W2120395042 @default.
• W2757005118 cites W2121183290 @default.
• W2757005118 cites W2128676800 @default.
• W2757005118 cites W2138420705 @default.
• W2757005118 cites W2143057278 @default.
• W2757005118 cites W2146631303 @default.
• W2757005118 cites W2159343161 @default.
• W2757005118 cites W2165108227 @default.
• W2757005118 cites W2178312212 @default.
• W2757005118 cites W2286968510 @default.
• W2757005118 cites W2332011491 @default.
• W2757005118 cites W2346864595 @default.
• W2757005118 cites W2409888425 @default.
• W2757005118 cites W2416801995 @default.
• W2757005118 cites W2475598822 @default.
• W2757005118 cites W2525592754 @default.
• W2757005118 cites W2559087812 @default.
• W2757005118 cites W2560835752 @default.
• W2757005118 cites W2564294648 @default.
• W2757005118 cites W2565740901 @default.
• W2757005118 cites W4247072139 @default.
• W2757005118 cites W4317923751 @default.
• W2757005118 doi "https://doi.org/10.1016/j.pnpbp.2017.09.027" @default.
• W2757005118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28965843" @default.
• W2757005118 hasPublicationYear "2018" @default.
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