FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2757264577> ?p ?o ?g. }

• W2757264577 endingPage "750" @default.
• W2757264577 startingPage "743" @default.
• W2757264577 abstract "Heparanase activity is involved in cancer growth and development in humans and single nucleotide polymorphisms (SNPs) in the heparanase gene (HPSE) have been shown to be associated with tumors. In this study, we investigated whether SNPs in HPSE were a risk factor for hepatocellular carcinoma (HCC) by undertaking a comprehensive haplotype-tagging, case-control study. For this, six haplotype-tagging SNPs (htSNPs) in HPSE were genotyped in 400 HCC patients and 480 controls by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis. A log-additive model revealed significant correlations between the HPSE polymorphisms rs12331678 and rs12503843 and the risk of HCC in the overall samples (p = 0.0046 and p = 0.0055). When the analysis was stratified based on hepatitis B virus (HBV) carrier status, significant interactions between rs12331678 and rs12503843 and HBV were observed. Conditional logistic regression analysis for the independent effect of one significant SNP suggested that rs12331678 or rs12503843 contributed an independent effect to the significant association with the risk of HCC, respectively. Our findings suggest that the SNPs rs12331678 and rs12503843 are HCC risk factors, although the potential functional roles of these two SNPs remain to be fully elucidated." @default.
• W2757264577 created "2017-10-06" @default.
• W2757264577 creator A5001769423 @default.
• W2757264577 creator A5013653434 @default.
• W2757264577 creator A5051480897 @default.
• W2757264577 creator A5053202587 @default.
• W2757264577 creator A5054139176 @default.
• W2757264577 creator A5058366891 @default.
• W2757264577 creator A5063592417 @default.
• W2757264577 creator A5072106006 @default.
• W2757264577 creator A5074899417 @default.
• W2757264577 creator A5078710220 @default.
• W2757264577 date "2017-10-02" @default.
• W2757264577 modified "2023-10-16" @default.
• W2757264577 title "Association of polymorphisms in the heparanase gene (HPSE) with hepatocellular carcinoma in Chinese populations" @default.
• W2757264577 cites W1665762888 @default.
• W2757264577 cites W1965001494 @default.
• W2757264577 cites W1975173354 @default.
• W2757264577 cites W1981989535 @default.
• W2757264577 cites W1996795546 @default.
• W2757264577 cites W1997483863 @default.
• W2757264577 cites W2003727136 @default.
• W2757264577 cites W2004055810 @default.
• W2757264577 cites W2008581828 @default.
• W2757264577 cites W2011208401 @default.
• W2757264577 cites W2015588350 @default.
• W2757264577 cites W2025369063 @default.
• W2757264577 cites W2030705868 @default.
• W2757264577 cites W2031251284 @default.
• W2757264577 cites W2036633274 @default.
• W2757264577 cites W2069783532 @default.
• W2757264577 cites W2086055165 @default.
• W2757264577 cites W2096289548 @default.
• W2757264577 cites W2100069865 @default.
• W2757264577 cites W2101535860 @default.
• W2757264577 cites W2107646761 @default.
• W2757264577 cites W2121051541 @default.
• W2757264577 cites W2147631692 @default.
• W2757264577 cites W2155528918 @default.
• W2757264577 cites W2159303900 @default.
• W2757264577 cites W2401555132 @default.
• W2757264577 cites W4245721392 @default.
• W2757264577 doi "https://doi.org/10.1590/1678-4685-gmb-2014-0338" @default.
• W2757264577 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5738625" @default.
• W2757264577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28981558" @default.
• W2757264577 hasPublicationYear "2017" @default.
• W2757264577 type Work @default.
• W2757264577 sameAs 2757264577 @default.
• W2757264577 citedByCount "4" @default.
• W2757264577 countsByYear W27572645772019 @default.
• W2757264577 countsByYear W27572645772020 @default.
• W2757264577 countsByYear W27572645772021 @default.
• W2757264577 crossrefType "journal-article" @default.
• W2757264577 hasAuthorship W2757264577A5001769423 @default.
• W2757264577 hasAuthorship W2757264577A5013653434 @default.
• W2757264577 hasAuthorship W2757264577A5051480897 @default.
• W2757264577 hasAuthorship W2757264577A5053202587 @default.
• W2757264577 hasAuthorship W2757264577A5054139176 @default.
• W2757264577 hasAuthorship W2757264577A5058366891 @default.
• W2757264577 hasAuthorship W2757264577A5063592417 @default.
• W2757264577 hasAuthorship W2757264577A5072106006 @default.
• W2757264577 hasAuthorship W2757264577A5074899417 @default.
• W2757264577 hasAuthorship W2757264577A5078710220 @default.
• W2757264577 hasBestOaLocation W27572645771 @default.
• W2757264577 hasConcept C104317684 @default.
• W2757264577 hasConcept C121608353 @default.
• W2757264577 hasConcept C126322002 @default.
• W2757264577 hasConcept C135763542 @default.
• W2757264577 hasConcept C139275648 @default.
• W2757264577 hasConcept C143998085 @default.
• W2757264577 hasConcept C153209595 @default.
• W2757264577 hasConcept C197754878 @default.
• W2757264577 hasConcept C2522874641 @default.
• W2757264577 hasConcept C2777478136 @default.
• W2757264577 hasConcept C2778019345 @default.
• W2757264577 hasConcept C2778997737 @default.
• W2757264577 hasConcept C2779013556 @default.
• W2757264577 hasConcept C2780593183 @default.
• W2757264577 hasConcept C509974204 @default.
• W2757264577 hasConcept C54355233 @default.
• W2757264577 hasConcept C71924100 @default.
• W2757264577 hasConcept C86803240 @default.
• W2757264577 hasConceptScore W2757264577C104317684 @default.
• W2757264577 hasConceptScore W2757264577C121608353 @default.
• W2757264577 hasConceptScore W2757264577C126322002 @default.
• W2757264577 hasConceptScore W2757264577C135763542 @default.
• W2757264577 hasConceptScore W2757264577C139275648 @default.
• W2757264577 hasConceptScore W2757264577C143998085 @default.
• W2757264577 hasConceptScore W2757264577C153209595 @default.
• W2757264577 hasConceptScore W2757264577C197754878 @default.
• W2757264577 hasConceptScore W2757264577C2522874641 @default.
• W2757264577 hasConceptScore W2757264577C2777478136 @default.
• W2757264577 hasConceptScore W2757264577C2778019345 @default.
• W2757264577 hasConceptScore W2757264577C2778997737 @default.
• W2757264577 hasConceptScore W2757264577C2779013556 @default.
• W2757264577 hasConceptScore W2757264577C2780593183 @default.
• W2757264577 hasConceptScore W2757264577C509974204 @default.
• W2757264577 hasConceptScore W2757264577C54355233 @default.

• next