FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2757876855> ?p ?o ?g. }

• W2757876855 endingPage "67" @default.
• W2757876855 startingPage "58" @default.
• W2757876855 abstract "Abstract This paper describes a straightforward and easy-to-implement method for comparing mass spectra using multivariate chemometric techniques in order to detect differences and obtain representative similarity metrics. For this purpose, we have programmed own MATLAB function called Protiago. Protiago successfully transforms complex vectors (i.e. intensities and m / z values from mass spectra) with different lengths in binary vectors with the same number of elements. In addition, Protiago is able to read and properly process a set of spectra vectors in order to carry out a proper similarity analysis using four similarity metrics (i.e. the coefficient of determination, the cosine of the angle, the Bray-Curtis index and the nearness index). The latter is a new similarity index proposed by the authors and applied for the first time in this study. It calculates a standardized Euclidean distance between two vectors in the space in order to obtain a numerical value, ranged between 0 and 1, of the proximity of both vectors. To supplement the similarity analysis information, two multivariate exploratory methods were applied, i.e. principal component analysis (PCA) and multivariate analysis of variance (MANOVA). As an example of the proposed method, the comparison of peptide mass fingerprints obtained using MALDI-TOF mass spectrometry from two therapeutical monoclonal antibodies, infliximab (INF) and rituximab (RTX), was carried out. By using this method it was possible detect changes in the primary structure of the two proteins in order to study their chemical stability for 7 days under two storage conditions (refrigerated at 4 °C, and frozen at −20 °C)." @default.
• W2757876855 created "2017-10-06" @default.
• W2757876855 creator A5018038327 @default.
• W2757876855 creator A5038652260 @default.
• W2757876855 creator A5060586453 @default.
• W2757876855 creator A5062503108 @default.
• W2757876855 date "2017-11-01" @default.
• W2757876855 modified "2023-10-18" @default.
• W2757876855 title "Method for the comparison of complex matrix assisted laser desorption ionization-time of flight mass spectra. Stability of therapeutical monoclonal antibodies" @default.
• W2757876855 cites W2030685682 @default.
• W2757876855 cites W2032881490 @default.
• W2757876855 cites W2035024255 @default.
• W2757876855 cites W2035756516 @default.
• W2757876855 cites W2048150858 @default.
• W2757876855 cites W2051950507 @default.
• W2757876855 cites W2072048943 @default.
• W2757876855 cites W2110286249 @default.
• W2757876855 cites W2147618390 @default.
• W2757876855 cites W2160139866 @default.
• W2757876855 cites W2163112013 @default.
• W2757876855 cites W2369825981 @default.
• W2757876855 cites W2399583684 @default.
• W2757876855 cites W2406164926 @default.
• W2757876855 cites W2414433514 @default.
• W2757876855 cites W2763148304 @default.
• W2757876855 cites W4235940105 @default.
• W2757876855 doi "https://doi.org/10.1016/j.chemolab.2017.09.008" @default.
• W2757876855 hasPublicationYear "2017" @default.
• W2757876855 type Work @default.
• W2757876855 sameAs 2757876855 @default.
• W2757876855 citedByCount "6" @default.
• W2757876855 countsByYear W27578768552018 @default.
• W2757876855 countsByYear W27578768552020 @default.
• W2757876855 countsByYear W27578768552022 @default.
• W2757876855 countsByYear W27578768552023 @default.
• W2757876855 crossrefType "journal-article" @default.
• W2757876855 hasAuthorship W2757876855A5018038327 @default.
• W2757876855 hasAuthorship W2757876855A5038652260 @default.
• W2757876855 hasAuthorship W2757876855A5060586453 @default.
• W2757876855 hasAuthorship W2757876855A5062503108 @default.
• W2757876855 hasConcept C106487976 @default.
• W2757876855 hasConcept C113196181 @default.
• W2757876855 hasConcept C121332964 @default.
• W2757876855 hasConcept C1276947 @default.
• W2757876855 hasConcept C145148216 @default.
• W2757876855 hasConcept C147789679 @default.
• W2757876855 hasConcept C150394285 @default.
• W2757876855 hasConcept C159654299 @default.
• W2757876855 hasConcept C162356407 @default.
• W2757876855 hasConcept C162711632 @default.
• W2757876855 hasConcept C16291436 @default.
• W2757876855 hasConcept C178790620 @default.
• W2757876855 hasConcept C185592680 @default.
• W2757876855 hasConcept C192562407 @default.
• W2757876855 hasConcept C198291218 @default.
• W2757876855 hasConcept C203014093 @default.
• W2757876855 hasConcept C40325409 @default.
• W2757876855 hasConcept C43617362 @default.
• W2757876855 hasConcept C4839761 @default.
• W2757876855 hasConcept C542903549 @default.
• W2757876855 hasConcept C71924100 @default.
• W2757876855 hasConcept C98960154 @default.
• W2757876855 hasConceptScore W2757876855C106487976 @default.
• W2757876855 hasConceptScore W2757876855C113196181 @default.
• W2757876855 hasConceptScore W2757876855C121332964 @default.
• W2757876855 hasConceptScore W2757876855C1276947 @default.
• W2757876855 hasConceptScore W2757876855C145148216 @default.
• W2757876855 hasConceptScore W2757876855C147789679 @default.
• W2757876855 hasConceptScore W2757876855C150394285 @default.
• W2757876855 hasConceptScore W2757876855C159654299 @default.
• W2757876855 hasConceptScore W2757876855C162356407 @default.
• W2757876855 hasConceptScore W2757876855C162711632 @default.
• W2757876855 hasConceptScore W2757876855C16291436 @default.
• W2757876855 hasConceptScore W2757876855C178790620 @default.
• W2757876855 hasConceptScore W2757876855C185592680 @default.
• W2757876855 hasConceptScore W2757876855C192562407 @default.
• W2757876855 hasConceptScore W2757876855C198291218 @default.
• W2757876855 hasConceptScore W2757876855C203014093 @default.
• W2757876855 hasConceptScore W2757876855C40325409 @default.
• W2757876855 hasConceptScore W2757876855C43617362 @default.
• W2757876855 hasConceptScore W2757876855C4839761 @default.
• W2757876855 hasConceptScore W2757876855C542903549 @default.
• W2757876855 hasConceptScore W2757876855C71924100 @default.
• W2757876855 hasConceptScore W2757876855C98960154 @default.
• W2757876855 hasLocation W27578768551 @default.
• W2757876855 hasOpenAccess W2757876855 @default.
• W2757876855 hasPrimaryLocation W27578768551 @default.
• W2757876855 hasRelatedWork W1972245467 @default.
• W2757876855 hasRelatedWork W2014259498 @default.
• W2757876855 hasRelatedWork W2033303661 @default.
• W2757876855 hasRelatedWork W2039221321 @default.
• W2757876855 hasRelatedWork W2052494781 @default.
• W2757876855 hasRelatedWork W2061341112 @default.
• W2757876855 hasRelatedWork W2115089515 @default.
• W2757876855 hasRelatedWork W2137528709 @default.
• W2757876855 hasRelatedWork W2325981527 @default.
• W2757876855 hasRelatedWork W3010828135 @default.
• W2757876855 hasVolume "170" @default.

• next