FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2758009818> ?p ?o ?g. }

• W2758009818 endingPage "28" @default.
• W2758009818 startingPage "21" @default.
• W2758009818 abstract "Carotenoids are plant pigment molecules that are potent antioxidants. Carotenoids cannot be synthesized de novo; therefore, their dietary intake and transport to various tissues are essential to harness their health benefits. Two of the three scavenger receptor class B (SRB) proteins, SR-B1 and CD36, have been implicated as carotenoid transporters in lower species and in various tissues of higher animals. The function of the third SRB protein, SR-B2, in carotenoid transport is unknown. Using surface plasmon resonance (SPR) analyses, we have determined that all three human SRB proteins are capable of binding the macular xanthophyll carotenoids; lutein, zeaxanthin, and meso-zeaxanthin. By over-expressing human SRB proteins in cells that do not endogenously express SRBs, we have determined that lutein uptake is enhanced in the presence of LDL and is mediated by SR-B1 and CD36. SR-B1, SR-B2, and CD36 were able to take up significant amounts of zeaxanthin as well as meso-zeaxanthin, and uptake was increased in the presence of HDL. Our analyses revealed no apparent differences in protein expression profiles of SRBs in central and peripheral regions of human donor tissues, indicating that carotenoid-binding proteins rather than transporters are likely to mediate selective accumulation of carotenoids into the macula." @default.
• W2758009818 created "2017-10-06" @default.
• W2758009818 creator A5004004204 @default.
• W2758009818 creator A5016525527 @default.
• W2758009818 creator A5020929451 @default.
• W2758009818 creator A5021661809 @default.
• W2758009818 creator A5029557286 @default.
• W2758009818 date "2017-11-01" @default.
• W2758009818 modified "2023-10-11" @default.
• W2758009818 title "All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids" @default.
• W2758009818 cites W151625338 @default.
• W2758009818 cites W1855180909 @default.
• W2758009818 cites W1932447330 @default.
• W2758009818 cites W1948539164 @default.
• W2758009818 cites W1967420021 @default.
• W2758009818 cites W1971090773 @default.
• W2758009818 cites W1980700229 @default.
• W2758009818 cites W1991274568 @default.
• W2758009818 cites W2007309421 @default.
• W2758009818 cites W2025894338 @default.
• W2758009818 cites W2036490840 @default.
• W2758009818 cites W2066260483 @default.
• W2758009818 cites W2072253833 @default.
• W2758009818 cites W2105811828 @default.
• W2758009818 cites W2108732045 @default.
• W2758009818 cites W2109860975 @default.
• W2758009818 cites W2116977711 @default.
• W2758009818 cites W2119194983 @default.
• W2758009818 cites W2119608540 @default.
• W2758009818 cites W2125295822 @default.
• W2758009818 cites W2127797389 @default.
• W2758009818 cites W2149841688 @default.
• W2758009818 cites W2151050370 @default.
• W2758009818 cites W2155732479 @default.
• W2758009818 cites W2275686904 @default.
• W2758009818 cites W2340339686 @default.
• W2758009818 cites W2508864126 @default.
• W2758009818 cites W2752317959 @default.
• W2758009818 doi "https://doi.org/10.1016/j.abb.2017.09.013" @default.
• W2758009818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5698089" @default.
• W2758009818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28947101" @default.
• W2758009818 hasPublicationYear "2017" @default.
• W2758009818 type Work @default.
• W2758009818 sameAs 2758009818 @default.
• W2758009818 citedByCount "33" @default.
• W2758009818 countsByYear W27580098182017 @default.
• W2758009818 countsByYear W27580098182018 @default.
• W2758009818 countsByYear W27580098182019 @default.
• W2758009818 countsByYear W27580098182020 @default.
• W2758009818 countsByYear W27580098182021 @default.
• W2758009818 countsByYear W27580098182022 @default.
• W2758009818 countsByYear W27580098182023 @default.
• W2758009818 crossrefType "journal-article" @default.
• W2758009818 hasAuthorship W2758009818A5004004204 @default.
• W2758009818 hasAuthorship W2758009818A5016525527 @default.
• W2758009818 hasAuthorship W2758009818A5020929451 @default.
• W2758009818 hasAuthorship W2758009818A5021661809 @default.
• W2758009818 hasAuthorship W2758009818A5029557286 @default.
• W2758009818 hasBestOaLocation W27580098182 @default.
• W2758009818 hasConcept C125575132 @default.
• W2758009818 hasConcept C170493617 @default.
• W2758009818 hasConcept C185592680 @default.
• W2758009818 hasConcept C2776099141 @default.
• W2758009818 hasConcept C2778163477 @default.
• W2758009818 hasConcept C2778411929 @default.
• W2758009818 hasConcept C2779828298 @default.
• W2758009818 hasConcept C2780072125 @default.
• W2758009818 hasConcept C28781525 @default.
• W2758009818 hasConcept C41443022 @default.
• W2758009818 hasConcept C55493867 @default.
• W2758009818 hasConcept C86803240 @default.
• W2758009818 hasConceptScore W2758009818C125575132 @default.
• W2758009818 hasConceptScore W2758009818C170493617 @default.
• W2758009818 hasConceptScore W2758009818C185592680 @default.
• W2758009818 hasConceptScore W2758009818C2776099141 @default.
• W2758009818 hasConceptScore W2758009818C2778163477 @default.
• W2758009818 hasConceptScore W2758009818C2778411929 @default.
• W2758009818 hasConceptScore W2758009818C2779828298 @default.
• W2758009818 hasConceptScore W2758009818C2780072125 @default.
• W2758009818 hasConceptScore W2758009818C28781525 @default.
• W2758009818 hasConceptScore W2758009818C41443022 @default.
• W2758009818 hasConceptScore W2758009818C55493867 @default.
• W2758009818 hasConceptScore W2758009818C86803240 @default.
• W2758009818 hasFunder F4320332161 @default.
• W2758009818 hasLocation W27580098181 @default.
• W2758009818 hasLocation W27580098182 @default.
• W2758009818 hasLocation W27580098183 @default.
• W2758009818 hasLocation W27580098184 @default.
• W2758009818 hasOpenAccess W2758009818 @default.
• W2758009818 hasPrimaryLocation W27580098181 @default.
• W2758009818 hasRelatedWork W180925084 @default.
• W2758009818 hasRelatedWork W1874791027 @default.
• W2758009818 hasRelatedWork W2029339810 @default.
• W2758009818 hasRelatedWork W2048380650 @default.
• W2758009818 hasRelatedWork W2052260720 @default.
• W2758009818 hasRelatedWork W2213481214 @default.
• W2758009818 hasRelatedWork W2230053621 @default.
• W2758009818 hasRelatedWork W2233592504 @default.

• next