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- W2758413708 abstract "The optimal target blood pressure (BP) in the treatment of hypertensive patients remains controversial. Recently, the systolic blood pressure trial (SPRINT) has proposed that a target systolic blood pressure of < 120 mmHg provides prognostic benefit in elderly hypertensive patients at high cardiovascular risk. The results of SPRINT contrast with several other intervention trials which have investigated the effect of intense BP lowering (Secondary Prevention of Small Subcortical Strokes [SPS3], Action to Control Cardiovascular Risk in Diabetes [ACCORD], Heart Outcomes Prevention Evaluation [HOPE]-3). The differences in outcomes in SPRINT vs. other intervention trials are, to a large extend, due to an unobserved BP measurement procedure utilized in the SPRINT trial. Thus, a BP goal of < 120 mmHg, at least by conventional BP measurement, remains unproven. Independent of SPRINT the controversial evidence with respect to BP targets calls for further studies and, possibly, for more individualized treatment goals." @default.
- W2758413708 created "2017-10-06" @default.
- W2758413708 creator A5000764134 @default.
- W2758413708 date "2017-09-01" @default.
- W2758413708 modified "2023-09-27" @default.
- W2758413708 title "Therapieziele bei der Hypertoniebehandlung" @default.
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- W2758413708 doi "https://doi.org/10.1055/s-0043-107269" @default.
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