Matches in SemOpenAlex for { <https://semopenalex.org/work/W2758498281> ?p ?o ?g. }
- W2758498281 abstract "Infection with Gram-negative bacteria is a major cause of aberrant inflammation in the oviduct; consequences can include tubal-based infertility and/or ectopic pregnancy. Understanding the inflammatory response is necessary for the development of novel treatment options that counter inflammation-induced infertility. The aim of the present study was to determine the effect of intraperitoneal (i.p.) administration of Escherichia coli-derived lipopolysaccharide (LPS) on the acute expression of inflammatory mRNAs and microRNAs (miRNAs) in the oviduct. On the day of oestrus, 6- to 8-week-old CD1 mice were injected i.p. with 0, 2 or 10 µg LPS in 100 μL phosphate-buffered saline. Mice were killed 24 h later and the oviducts collected for gene expression analyses. The effect of treatment on the expression of mRNAs and miRNAs was evaluated by one-way analysis of variance (ANOVA), with treatment means of differentially expressed (P < 0.05) transcripts separated using Scheffé’s test. LPS treatment affected 49 of 179 targeted inflammatory mRNAs and 51 of 578 miRNAs (P < 0.05). The identity of differentially expressed miRNAs predicted as regulators of chemokine and interleukin ligand mRNAs was then extracted using the microRNA.org database. The results of the present study indicate that systemic treatment with LPS induces a robust inflammatory response in the oviducts of mice, and identify key mRNAs and putative miRNAs modulating this effect." @default.
- W2758498281 created "2017-10-06" @default.
- W2758498281 creator A5004661360 @default.
- W2758498281 creator A5014270309 @default.
- W2758498281 creator A5017221653 @default.
- W2758498281 creator A5053780153 @default.
- W2758498281 creator A5090362895 @default.
- W2758498281 date "2018-01-01" @default.
- W2758498281 modified "2023-10-14" @default.
- W2758498281 title "Effect of lipopolysaccharide on the expression of inflammatory mRNAs and microRNAs in the mouse oviduct" @default.
- W2758498281 cites W1689603631 @default.
- W2758498281 cites W1711544787 @default.
- W2758498281 cites W1965751633 @default.
- W2758498281 cites W1967313249 @default.
- W2758498281 cites W1970440778 @default.
- W2758498281 cites W1973573335 @default.
- W2758498281 cites W1977540238 @default.
- W2758498281 cites W1984866315 @default.
- W2758498281 cites W1988969478 @default.
- W2758498281 cites W1989219560 @default.
- W2758498281 cites W1999852922 @default.
- W2758498281 cites W2000153769 @default.
- W2758498281 cites W2006588703 @default.
- W2758498281 cites W2008484972 @default.
- W2758498281 cites W2009166328 @default.
- W2758498281 cites W2019241761 @default.
- W2758498281 cites W2020541351 @default.
- W2758498281 cites W2021759928 @default.
- W2758498281 cites W2036891449 @default.
- W2758498281 cites W2041509376 @default.
- W2758498281 cites W2048009279 @default.
- W2758498281 cites W2060975209 @default.
- W2758498281 cites W2068035089 @default.
- W2758498281 cites W2077888633 @default.
- W2758498281 cites W2078541812 @default.
- W2758498281 cites W2094901227 @default.
- W2758498281 cites W2098114556 @default.
- W2758498281 cites W2104537148 @default.
- W2758498281 cites W2104918497 @default.
- W2758498281 cites W2105727196 @default.
- W2758498281 cites W2107277218 @default.
- W2758498281 cites W2115807816 @default.
- W2758498281 cites W2120950950 @default.
- W2758498281 cites W2121563779 @default.
- W2758498281 cites W2127751957 @default.
- W2758498281 cites W2133658633 @default.
- W2758498281 cites W2134917885 @default.
- W2758498281 cites W2140398232 @default.
- W2758498281 cites W2143596855 @default.
- W2758498281 cites W2145070308 @default.
- W2758498281 cites W2156178538 @default.
- W2758498281 cites W2156861863 @default.
- W2758498281 cites W2157511209 @default.
- W2758498281 cites W2168745915 @default.
- W2758498281 cites W2170124538 @default.
- W2758498281 cites W2239797373 @default.
- W2758498281 cites W2297754275 @default.
- W2758498281 cites W2314682488 @default.
- W2758498281 cites W2484877107 @default.
- W2758498281 cites W4230911957 @default.
- W2758498281 cites W4234317413 @default.
- W2758498281 doi "https://doi.org/10.1071/rd17241" @default.
- W2758498281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28945983" @default.
- W2758498281 hasPublicationYear "2018" @default.
- W2758498281 type Work @default.
- W2758498281 sameAs 2758498281 @default.
- W2758498281 citedByCount "0" @default.
- W2758498281 crossrefType "journal-article" @default.
- W2758498281 hasAuthorship W2758498281A5004661360 @default.
- W2758498281 hasAuthorship W2758498281A5014270309 @default.
- W2758498281 hasAuthorship W2758498281A5017221653 @default.
- W2758498281 hasAuthorship W2758498281A5053780153 @default.
- W2758498281 hasAuthorship W2758498281A5090362895 @default.
- W2758498281 hasConcept C104317684 @default.
- W2758498281 hasConcept C13373296 @default.
- W2758498281 hasConcept C134018914 @default.
- W2758498281 hasConcept C145059251 @default.
- W2758498281 hasConcept C150194340 @default.
- W2758498281 hasConcept C153911025 @default.
- W2758498281 hasConcept C16685009 @default.
- W2758498281 hasConcept C203014093 @default.
- W2758498281 hasConcept C2776914184 @default.
- W2758498281 hasConcept C2777129507 @default.
- W2758498281 hasConcept C2777688143 @default.
- W2758498281 hasConcept C2778754761 @default.
- W2758498281 hasConcept C2779234561 @default.
- W2758498281 hasConcept C54355233 @default.
- W2758498281 hasConcept C71924100 @default.
- W2758498281 hasConcept C86803240 @default.
- W2758498281 hasConceptScore W2758498281C104317684 @default.
- W2758498281 hasConceptScore W2758498281C13373296 @default.
- W2758498281 hasConceptScore W2758498281C134018914 @default.
- W2758498281 hasConceptScore W2758498281C145059251 @default.
- W2758498281 hasConceptScore W2758498281C150194340 @default.
- W2758498281 hasConceptScore W2758498281C153911025 @default.
- W2758498281 hasConceptScore W2758498281C16685009 @default.
- W2758498281 hasConceptScore W2758498281C203014093 @default.
- W2758498281 hasConceptScore W2758498281C2776914184 @default.
- W2758498281 hasConceptScore W2758498281C2777129507 @default.
- W2758498281 hasConceptScore W2758498281C2777688143 @default.