Matches in SemOpenAlex for { <https://semopenalex.org/work/W2758744229> ?p ?o ?g. }
- W2758744229 endingPage "861" @default.
- W2758744229 startingPage "846" @default.
- W2758744229 abstract "Summary Plasmodesmata ( PD ), unique to the plant kingdom, are structurally complex microchannels that cross the cell wall to establish symplastic communication between neighbouring cells. Viral intercellular movement occurs through PD . To better understand the involvement of PD in viral infection, we conducted a quantitative proteomic study on the PD ‐enriched fraction from Nicotiana benthamiana leaves in response to infection by Turnip mosaic virus (Tu MV ). We report the identification of a total of 1070 PD protein candidates, of which 100 (≥2‐fold increase) and 48 (≥2‐fold reduction) are significantly differentially accumulated in the PD ‐enriched fraction, when compared with protein levels in the corresponding healthy control. Among the differentially accumulated PD protein candidates, we show that an α‐expansin designated Nb EXPA 1, a cell wall loosening protein, is PD ‐specific. Tu MV infection downregulates Nb EXPA 1 mRNA expression and protein accumulation. We further demonstrate that Nb EXPA 1 is recruited to the viral replication complex via the interaction with NI b, the only RNA ‐dependent RNA polymerase of Tu MV . Silencing of Nb EXPA 1 inhibits plant growth and Tu MV infection, whereas overexpression of Nb EXPA 1 promotes viral replication and intercellular movement. These data suggest that Nb EXPA 1 is a host factor for potyviral infection. This study not only generates a PD ‐proteome dataset that is useful in future studies to expound PD biology and PD ‐mediated virus–host interactions but also characterizes Nb EXPA 1 as the first PD ‐specific cell wall loosening protein and its essential role in potyviral infection." @default.
- W2758744229 created "2017-10-06" @default.
- W2758744229 creator A5013169889 @default.
- W2758744229 creator A5040124787 @default.
- W2758744229 creator A5048523292 @default.
- W2758744229 creator A5054012489 @default.
- W2758744229 creator A5055982663 @default.
- W2758744229 creator A5065701342 @default.
- W2758744229 creator A5066005897 @default.
- W2758744229 creator A5075411450 @default.
- W2758744229 creator A5081202199 @default.
- W2758744229 date "2017-11-17" @default.
- W2758744229 modified "2023-10-12" @default.
- W2758744229 title "NbEXPA1, an α‐expansin, is plasmodesmata‐specific and a novel host factor for potyviral infection" @default.
- W2758744229 cites W1800847167 @default.
- W2758744229 cites W1828149617 @default.
- W2758744229 cites W1886507932 @default.
- W2758744229 cites W1926826741 @default.
- W2758744229 cites W1942019064 @default.
- W2758744229 cites W1957571100 @default.
- W2758744229 cites W1967547967 @default.
- W2758744229 cites W1969353942 @default.
- W2758744229 cites W1971924348 @default.
- W2758744229 cites W1973057648 @default.
- W2758744229 cites W1973260273 @default.
- W2758744229 cites W1973731551 @default.
- W2758744229 cites W1978439509 @default.
- W2758744229 cites W1980400357 @default.
- W2758744229 cites W1985160283 @default.
- W2758744229 cites W1992512552 @default.
- W2758744229 cites W2001191731 @default.
- W2758744229 cites W2011466044 @default.
- W2758744229 cites W2013124267 @default.
- W2758744229 cites W2018171099 @default.
- W2758744229 cites W2018322506 @default.
- W2758744229 cites W2018430463 @default.
- W2758744229 cites W2023001306 @default.
- W2758744229 cites W2025479911 @default.
- W2758744229 cites W2035404796 @default.
- W2758744229 cites W2038555068 @default.
- W2758744229 cites W2043826840 @default.
- W2758744229 cites W2047995004 @default.
- W2758744229 cites W2059552594 @default.
- W2758744229 cites W2060078754 @default.
- W2758744229 cites W2067348599 @default.
- W2758744229 cites W2068830600 @default.
- W2758744229 cites W2077856929 @default.
- W2758744229 cites W2079239646 @default.
- W2758744229 cites W2080752012 @default.
- W2758744229 cites W2080929480 @default.
- W2758744229 cites W2081773176 @default.
- W2758744229 cites W2082378699 @default.
- W2758744229 cites W2082909190 @default.
- W2758744229 cites W2089031128 @default.
- W2758744229 cites W2092053018 @default.
- W2758744229 cites W2093437187 @default.
- W2758744229 cites W2093484541 @default.
- W2758744229 cites W2094201044 @default.
- W2758744229 cites W2096192175 @default.
- W2758744229 cites W2099750055 @default.
- W2758744229 cites W2100988810 @default.
- W2758744229 cites W2101028370 @default.
- W2758744229 cites W2101581180 @default.
- W2758744229 cites W2102721610 @default.
- W2758744229 cites W2103249145 @default.
- W2758744229 cites W2109035143 @default.
- W2758744229 cites W2109187906 @default.
- W2758744229 cites W2112231811 @default.
- W2758744229 cites W2112577372 @default.
- W2758744229 cites W2114321548 @default.
- W2758744229 cites W2119477250 @default.
- W2758744229 cites W2121360165 @default.
- W2758744229 cites W2125217346 @default.
- W2758744229 cites W2125802029 @default.
- W2758744229 cites W2128551987 @default.
- W2758744229 cites W2133044145 @default.
- W2758744229 cites W2137553842 @default.
- W2758744229 cites W2138641013 @default.
- W2758744229 cites W2141429272 @default.
- W2758744229 cites W2151806057 @default.
- W2758744229 cites W2154354934 @default.
- W2758744229 cites W2165243968 @default.
- W2758744229 cites W2170825900 @default.
- W2758744229 cites W2171805686 @default.
- W2758744229 cites W2175485020 @default.
- W2758744229 cites W2184738469 @default.
- W2758744229 cites W2187645922 @default.
- W2758744229 cites W2188912514 @default.
- W2758744229 cites W2259792993 @default.
- W2758744229 cites W2284349707 @default.
- W2758744229 cites W2325103100 @default.
- W2758744229 cites W2343639134 @default.
- W2758744229 cites W2400520586 @default.
- W2758744229 cites W2413385656 @default.
- W2758744229 cites W2418609321 @default.
- W2758744229 cites W2480451908 @default.
- W2758744229 cites W2511091302 @default.
- W2758744229 cites W2513814202 @default.