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• W2758767524 endingPage "273" @default.
• W2758767524 startingPage "273" @default.
• W2758767524 abstract "Begomoviruses are vectored in a circulative persistent manner by the whitefly Bemisia tabaci. The insect ingests viral particles with its stylets. Virions pass along the food canal and reach the esophagus and the midgut. They cross the filter chamber and the midgut into the haemolymph, translocate into the primary salivary glands and are egested with the saliva into the plant phloem. Begomoviruses have to cross several barriers and checkpoints successfully, while interacting with would-be receptors and other whitefly proteins. The bulk of the virus remains associated with the midgut and the filter chamber. In these tissues, viral genomes, mainly from the tomato yellow leaf curl virus (TYLCV) family, may be transcribed and may replicate. However, at the same time, virus amounts peak, and the insect autophagic response is activated, which in turn inhibits replication and induces the destruction of the virus. Some begomoviruses invade tissues outside the circulative pathway, such as ovaries and fat cells. Autophagy limits the amounts of virus associated with these organs. In this review, we discuss the different sites begomoviruses need to cross to complete a successful circular infection, the role of the coat protein in this process and the sites that balance between virus accumulation and virus destruction." @default.
• W2758767524 created "2017-10-06" @default.
• W2758767524 creator A5010482447 @default.
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• W2758767524 creator A5017116967 @default.
• W2758767524 creator A5066422363 @default.
• W2758767524 creator A5085869563 @default.
• W2758767524 date "2017-09-24" @default.
• W2758767524 modified "2023-10-18" @default.
• W2758767524 title "The Incredible Journey of Begomoviruses in Their Whitefly Vector" @default.
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• W2758767524 doi "https://doi.org/10.3390/v9100273" @default.
• W2758767524 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5691625" @default.
• W2758767524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28946649" @default.

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