FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2758835369> ?p ?o ?g. }

• W2758835369 endingPage "205" @default.
• W2758835369 startingPage "197" @default.
• W2758835369 abstract "Adipsic hypernatremia is a rare disease presenting as persistent hypernatremia with disturbance of thirst regulation and hypothalamic dysfunction. As a result of congenital disease, tumors, or inflammation, most cases are accompanied by structural abnormalities in the hypothalamic-pituitary area. While cases with no hypothalamic-pituitary structural lesion have been reported, their etiology has not been elucidated. Recently, we reported three patients with adipsic hypernatremia whose serum-derived immunoglobulin (Ig) specifically reacted with mouse subfornical organ (SFO) tissue. As one of the circumventricular organs (CVOs) that form a sensory interface between the blood and brain, the SFO is a critical site for generating physiological responses to dehydration and hypernatremia. Intravenous injection of the patient’s Ig fraction induced hypernatremia in mice, along with inflammation and apoptosis in the SFO. These results support a new autoimmunity-related mechanism for inducing adipsic hypernatremia without demonstrable hypothalamic-pituitary structural lesions. In this review, we aim to highlight the characteristic clinical features of these patients, in addition to etiological mechanisms related to SFO function. These findings may be useful for diagnosing adipsic hypernatremia caused by an autoimmune response to the SFO, and support development of new strategies for prevention and treatment." @default.
• W2758835369 created "2017-10-06" @default.
• W2758835369 creator A5007417706 @default.
• W2758835369 creator A5021431246 @default.
• W2758835369 creator A5027300481 @default.
• W2758835369 creator A5029038415 @default.
• W2758835369 creator A5030970846 @default.
• W2758835369 date "2017-01-01" @default.
• W2758835369 modified "2023-10-07" @default.
• W2758835369 title "Characteristic clinical features of adipsic hypernatremia patients with subfornical organ-targeting antibody" @default.
• W2758835369 cites W1607299816 @default.
• W2758835369 cites W162205626 @default.
• W2758835369 cites W1637971961 @default.
• W2758835369 cites W1639503045 @default.
• W2758835369 cites W1969989097 @default.
• W2758835369 cites W1970096729 @default.
• W2758835369 cites W1972953707 @default.
• W2758835369 cites W1975327379 @default.
• W2758835369 cites W1977488173 @default.
• W2758835369 cites W1983986289 @default.
• W2758835369 cites W1985271502 @default.
• W2758835369 cites W2000359682 @default.
• W2758835369 cites W2003349875 @default.
• W2758835369 cites W2006941910 @default.
• W2758835369 cites W2014952196 @default.
• W2758835369 cites W2017154095 @default.
• W2758835369 cites W2019569144 @default.
• W2758835369 cites W2023262819 @default.
• W2758835369 cites W2033110150 @default.
• W2758835369 cites W2035107170 @default.
• W2758835369 cites W2037250847 @default.
• W2758835369 cites W2057966179 @default.
• W2758835369 cites W2080514050 @default.
• W2758835369 cites W2101424648 @default.
• W2758835369 cites W2111753781 @default.
• W2758835369 cites W2117766577 @default.
• W2758835369 cites W2131437319 @default.
• W2758835369 cites W2139652346 @default.
• W2758835369 cites W2150678055 @default.
• W2758835369 cites W2163865122 @default.
• W2758835369 cites W2172080321 @default.
• W2758835369 cites W2172465647 @default.
• W2758835369 cites W2174975492 @default.
• W2758835369 cites W2343630105 @default.
• W2758835369 cites W2471181136 @default.
• W2758835369 cites W2519953634 @default.
• W2758835369 cites W2564293300 @default.
• W2758835369 cites W2797871317 @default.
• W2758835369 cites W4233284663 @default.
• W2758835369 doi "https://doi.org/10.1297/cpe.26.197" @default.
• W2758835369 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5627220" @default.
• W2758835369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29026268" @default.
• W2758835369 hasPublicationYear "2017" @default.
• W2758835369 type Work @default.
• W2758835369 sameAs 2758835369 @default.
• W2758835369 citedByCount "11" @default.
• W2758835369 countsByYear W27588353692019 @default.
• W2758835369 countsByYear W27588353692020 @default.
• W2758835369 countsByYear W27588353692021 @default.
• W2758835369 countsByYear W27588353692022 @default.
• W2758835369 crossrefType "journal-article" @default.
• W2758835369 hasAuthorship W2758835369A5007417706 @default.
• W2758835369 hasAuthorship W2758835369A5021431246 @default.
• W2758835369 hasAuthorship W2758835369A5027300481 @default.
• W2758835369 hasAuthorship W2758835369A5029038415 @default.
• W2758835369 hasAuthorship W2758835369A5030970846 @default.
• W2758835369 hasBestOaLocation W27588353691 @default.
• W2758835369 hasConcept C126322002 @default.
• W2758835369 hasConcept C134018914 @default.
• W2758835369 hasConcept C137627325 @default.
• W2758835369 hasConcept C170493617 @default.
• W2758835369 hasConcept C178790620 @default.
• W2758835369 hasConcept C185592680 @default.
• W2758835369 hasConcept C203014093 @default.
• W2758835369 hasConcept C2775857624 @default.
• W2758835369 hasConcept C2776958162 @default.
• W2758835369 hasConcept C2777003273 @default.
• W2758835369 hasConcept C2777619780 @default.
• W2758835369 hasConcept C2778713406 @default.
• W2758835369 hasConcept C2778864100 @default.
• W2758835369 hasConcept C2908929049 @default.
• W2758835369 hasConcept C537181965 @default.
• W2758835369 hasConcept C71924100 @default.
• W2758835369 hasConceptScore W2758835369C126322002 @default.
• W2758835369 hasConceptScore W2758835369C134018914 @default.
• W2758835369 hasConceptScore W2758835369C137627325 @default.
• W2758835369 hasConceptScore W2758835369C170493617 @default.
• W2758835369 hasConceptScore W2758835369C178790620 @default.
• W2758835369 hasConceptScore W2758835369C185592680 @default.
• W2758835369 hasConceptScore W2758835369C203014093 @default.
• W2758835369 hasConceptScore W2758835369C2775857624 @default.
• W2758835369 hasConceptScore W2758835369C2776958162 @default.
• W2758835369 hasConceptScore W2758835369C2777003273 @default.
• W2758835369 hasConceptScore W2758835369C2777619780 @default.
• W2758835369 hasConceptScore W2758835369C2778713406 @default.
• W2758835369 hasConceptScore W2758835369C2778864100 @default.
• W2758835369 hasConceptScore W2758835369C2908929049 @default.
• W2758835369 hasConceptScore W2758835369C537181965 @default.

• next