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• W2758967567 abstract "Objective: To validate the FLAME (Fatality by Longevity, APACHE II score and Measured Entent of bum) score for outcome prediction in bum patients. Design: Multi-centre prospective study. Setting: Five Canadian burn centres: Hamilton (ON), St. John (NB). Toronto (ON), Vancouver (BC), and Windsor (ON). Patiene 527 adult bum patients (1997-1998). Outcorne: Hospi ta1 mortality . Resuits: The typical patient was a man (69%) with mean age of 44 years, mean body area bwed of 17%, and mean hospital stay of 19 days. There were 76 deaths (14%). The FLAME score was the simplest logistic mode1 with strong agreement between observed and predicted deaths (ROC area = 0.96). Using 2x2 classification table with 0.5 predicted risk of death, patients were comtly classified 94% of the time. Sensitivity: 68%, specificity: 9856, and positive likeiihad ratio: 34 were found. Conclusion: The FLAME score is a valid mortality predictive twl for bum patients. ACKNOWLEDGEMENTS = -A 2 This diesis is dedicated to Dr. Joel S. Fish, medical director of the Ross Tilley Burn Centre program, at the Sunnybrodr & Women's College Health Sciences Centre, and menber of my thesis comrnittee, who gave me the oppomuiity to increase my knowledge, skills and experience in burn management, reconstructive surgery, and bum research. Joel's continuous encouragement, wise advice and great enthusiasm, have been of paramount importance for the completion of this research study. 1 am deeply indebted with my thesis supervisor, Dr. Donald Redelmeier, whose expert advice, and invaluable support, had inspird me to complete this thesis. 1 would also like to thank Dr. John Paul Szalai, member of my thesis cornmittee, and Marko Katic, statistician, who gave me the extraordinary statistical support and guidance for the analysis of this study data. 1 would also like to thank Dr. David T. Wong, critical care specialist and anaesthesiologist, who gave me the opportunity to leam, administer and evaluate the APACHE II scoring system in severely il1 critical care patients. Special thanks to Dr. Thomas Stewart, critical care specialist, who stimulated me to conduct the initial retrospective analysis of outcome predictors in b u m patients. 1 would like to express my sincere gratitude to the medical directors of this study pdcipating bum centres: Dr. Janet Sproat (Hamilton, ON), Dr. H. Lalonde (St. John, NB), Dr. James Boyle (Vancouver, BC), and Dr. B. Snowdon (Windsor, ON), for their invaluable cooperation. 1 would like to thank the Work and Health Program of the Ontario Workplace Safety & Insurance Board for awarding me the scholarship to complete this thesis. Lastly, 1 would like to thank my family, whose eternal love, pemanent support, unlimited patience and generosity, have made possible the successfbl journey of my medical education, surgical training, and professional activities." @default.
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• W2758967567 date "2001-01-01" @default.
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• W2758967567 title "Predicting death in burn patients" @default.
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