Matches in SemOpenAlex for { <https://semopenalex.org/work/W2759026991> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2759026991 endingPage "82" @default.
- W2759026991 startingPage "75" @default.
- W2759026991 abstract "Introduction and Aims: Acute and chronic heart failure may manifest different degrees of endothelial damage and angiogenesis. Circulating endothelial cells (CEC) have been identified as marker of vascular damage. The aim of our study was to evaluate the evolution of the CEC at different stages of patients with heart failure. We also investigated a potential correlation between CEC and markers of vascular damage and angiogenesis. Methods: We studied 32 heart failure patients at hospital admission (acute phase) and at revision after 3 months (stable phase) and 32 controls. Circulating markers of endothelial damage (CEC; von Willebrand factor, vWF and soluble E-selectin, sEsel) and angiogenesis (vascular endothelial growth factor, VEGF and thrombospondin-1) were quantified. Results: Levels of CEC, vWF, sEsel and VEGF are significantly higher in heart failure patients than in controls. Levels of CEC (36.9 ± 15.3 vs. 21.5 ± 10.0 cells/ml; p < 0.001), vWF (325 ± 101 vs. 231 ± 82%; p < 0.001) and VEGF (26.3 ± 15.2 vs. 21.9 ± 11.9 ng/ml; p < 0.001) are significantly higher in the acute phase than in the stable phase of heart failure. CEC levels correlate with vWF and VEGF. Results show than 100% of patients in acute phase and 37.5% in stable phase have levels of CEC higher than the 99th percentile of the distribution of controls (16 cells/ml). Therefore, increases in CEC represent a relative risk of 9.5 for heart failure patients suffering from acute phase. Conclusions: CEC, in addition to being elevated in heart failure, correlate with vWF levels, providing further support for CEC as markers of endothelial damage. Levels of CEC are associated with the acute phase of heart failure and could be used as a marker of the worsening in heart failure." @default.
- W2759026991 created "2017-10-06" @default.
- W2759026991 creator A5004466207 @default.
- W2759026991 creator A5007441004 @default.
- W2759026991 creator A5018808691 @default.
- W2759026991 creator A5043490633 @default.
- W2759026991 creator A5075161508 @default.
- W2759026991 creator A5085690750 @default.
- W2759026991 date "2011-01-01" @default.
- W2759026991 modified "2023-10-17" @default.
- W2759026991 title "Circulating Endothelial Cells in Patients with Heart Failure and Left Ventricular Dysfunction" @default.
- W2759026991 cites W1918540162 @default.
- W2759026991 cites W1967586814 @default.
- W2759026991 cites W1968539943 @default.
- W2759026991 cites W1976460214 @default.
- W2759026991 cites W1977112395 @default.
- W2759026991 cites W1978427224 @default.
- W2759026991 cites W2020600709 @default.
- W2759026991 cites W2021448917 @default.
- W2759026991 cites W2022181032 @default.
- W2759026991 cites W2036491754 @default.
- W2759026991 cites W2039150609 @default.
- W2759026991 cites W2040805775 @default.
- W2759026991 cites W2048515649 @default.
- W2759026991 cites W2051252262 @default.
- W2759026991 cites W2052341105 @default.
- W2759026991 cites W2057313292 @default.
- W2759026991 cites W2071969279 @default.
- W2759026991 cites W2073136932 @default.
- W2759026991 cites W2079730469 @default.
- W2759026991 cites W2084837257 @default.
- W2759026991 cites W2109680555 @default.
- W2759026991 cites W2134388588 @default.
- W2759026991 cites W2157439567 @default.
- W2759026991 cites W2181350280 @default.
- W2759026991 cites W2187246504 @default.
- W2759026991 doi "https://doi.org/10.1155/2011/757840" @default.
- W2759026991 hasPublicationYear "2011" @default.
- W2759026991 type Work @default.
- W2759026991 sameAs 2759026991 @default.
- W2759026991 citedByCount "11" @default.
- W2759026991 countsByYear W27590269912013 @default.
- W2759026991 countsByYear W27590269912015 @default.
- W2759026991 countsByYear W27590269912016 @default.
- W2759026991 countsByYear W27590269912019 @default.
- W2759026991 countsByYear W27590269912022 @default.
- W2759026991 countsByYear W27590269912023 @default.
- W2759026991 crossrefType "journal-article" @default.
- W2759026991 hasAuthorship W2759026991A5004466207 @default.
- W2759026991 hasAuthorship W2759026991A5007441004 @default.
- W2759026991 hasAuthorship W2759026991A5018808691 @default.
- W2759026991 hasAuthorship W2759026991A5043490633 @default.
- W2759026991 hasAuthorship W2759026991A5075161508 @default.
- W2759026991 hasAuthorship W2759026991A5085690750 @default.
- W2759026991 hasBestOaLocation W27590269911 @default.
- W2759026991 hasConcept C126322002 @default.
- W2759026991 hasConcept C164705383 @default.
- W2759026991 hasConcept C167734588 @default.
- W2759026991 hasConcept C2777025900 @default.
- W2759026991 hasConcept C2778198053 @default.
- W2759026991 hasConcept C2779394231 @default.
- W2759026991 hasConcept C2780394083 @default.
- W2759026991 hasConcept C2780972559 @default.
- W2759026991 hasConcept C71924100 @default.
- W2759026991 hasConcept C89560881 @default.
- W2759026991 hasConceptScore W2759026991C126322002 @default.
- W2759026991 hasConceptScore W2759026991C164705383 @default.
- W2759026991 hasConceptScore W2759026991C167734588 @default.
- W2759026991 hasConceptScore W2759026991C2777025900 @default.
- W2759026991 hasConceptScore W2759026991C2778198053 @default.
- W2759026991 hasConceptScore W2759026991C2779394231 @default.
- W2759026991 hasConceptScore W2759026991C2780394083 @default.
- W2759026991 hasConceptScore W2759026991C2780972559 @default.
- W2759026991 hasConceptScore W2759026991C71924100 @default.
- W2759026991 hasConceptScore W2759026991C89560881 @default.
- W2759026991 hasFunder F4320322930 @default.
- W2759026991 hasIssue "2" @default.
- W2759026991 hasLocation W27590269911 @default.
- W2759026991 hasLocation W27590269912 @default.
- W2759026991 hasOpenAccess W2759026991 @default.
- W2759026991 hasPrimaryLocation W27590269911 @default.
- W2759026991 hasRelatedWork W140163974 @default.
- W2759026991 hasRelatedWork W1975903478 @default.
- W2759026991 hasRelatedWork W1985222413 @default.
- W2759026991 hasRelatedWork W2020600709 @default.
- W2759026991 hasRelatedWork W2039995053 @default.
- W2759026991 hasRelatedWork W2063007996 @default.
- W2759026991 hasRelatedWork W2076843464 @default.
- W2759026991 hasRelatedWork W2356933011 @default.
- W2759026991 hasRelatedWork W2389557435 @default.
- W2759026991 hasRelatedWork W4247718175 @default.
- W2759026991 hasVolume "31" @default.
- W2759026991 isParatext "false" @default.
- W2759026991 isRetracted "false" @default.
- W2759026991 magId "2759026991" @default.
- W2759026991 workType "article" @default.