FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2759231887> ?p ?o ?g. }

• W2759231887 endingPage "299" @default.
• W2759231887 startingPage "294" @default.
• W2759231887 abstract "Mast cells (MCs) are implicated in an array of diseases, especially those involving a mucosal surface, including intestine. On appropriate activation from cytoplasmatic granules, MCs release preformed chemical mediators and generate inflammatory lipids and cytokines/chemokines. Intracellular signal and Lyn activation pathways can cause the degranulation of MCs and the generation of lipid mediators and cytokines/chemokines. MCs undergo maturation and polarization in gut mucosal surfaces where they are constitutively present, and can alter intestinal permeability, an important factor in many inflammatory mucosal disorders including autoimmune diseases. On the other hand, since they are immununosuppressive, MCs have potential anti-inflammatory properties by producing TGF-β1, interleukin (IL)-4, IL-10, IL-13 and histamine. In addition, MC chymase, located in the sub-mucosa, acts on intestinal permeability by protecting the bowel. To carry the inflammatory response, MCs need to be attracted by CC chemokines such as RANTES (CCL5) and MCP-1(CCL2), an effect absent in genetically W/Wv mast cell-deficient mice, where the inflammatory reaction is not present. Here, we focused our attention on recent findings regarding how MCs can initiate and develop the cellular immune response in the gut and mediate inflammation, an effect that can be inhibited by IL-37. These studies contribute to clarify the mechanisms by which MCs profoundly affect immunity and inflammation of the intestine." @default.
• W2759231887 created "2017-10-06" @default.
• W2759231887 creator A5000139771 @default.
• W2759231887 creator A5021257221 @default.
• W2759231887 creator A5054106836 @default.
• W2759231887 creator A5071941913 @default.
• W2759231887 creator A5077573350 @default.
• W2759231887 creator A5085356549 @default.
• W2759231887 creator A5087329343 @default.
• W2759231887 date "2018-01-01" @default.
• W2759231887 modified "2023-09-25" @default.
• W2759231887 title "Impact of mast cells in mucosal immunity of intestinal inflammation: Inhibitory effect of IL-37" @default.
• W2759231887 cites W115070922 @default.
• W2759231887 cites W1516355571 @default.
• W2759231887 cites W1524632935 @default.
• W2759231887 cites W1603039868 @default.
• W2759231887 cites W1607957872 @default.
• W2759231887 cites W1779434421 @default.
• W2759231887 cites W1792432231 @default.
• W2759231887 cites W1924842828 @default.
• W2759231887 cites W1937792941 @default.
• W2759231887 cites W1963808807 @default.
• W2759231887 cites W1967311384 @default.
• W2759231887 cites W1967629432 @default.
• W2759231887 cites W1968206308 @default.
• W2759231887 cites W1976118863 @default.
• W2759231887 cites W1977761329 @default.
• W2759231887 cites W1979375310 @default.
• W2759231887 cites W1979873552 @default.
• W2759231887 cites W1989287592 @default.
• W2759231887 cites W2001140826 @default.
• W2759231887 cites W2007298827 @default.
• W2759231887 cites W2016482156 @default.
• W2759231887 cites W2023731445 @default.
• W2759231887 cites W2028190708 @default.
• W2759231887 cites W2038511363 @default.
• W2759231887 cites W2046456597 @default.
• W2759231887 cites W2070975187 @default.
• W2759231887 cites W2079678457 @default.
• W2759231887 cites W2099660723 @default.
• W2759231887 cites W2108798510 @default.
• W2759231887 cites W2111613296 @default.
• W2759231887 cites W2116448165 @default.
• W2759231887 cites W2118752824 @default.
• W2759231887 cites W2135525156 @default.
• W2759231887 cites W2152131300 @default.
• W2759231887 cites W2152336072 @default.
• W2759231887 cites W2152710382 @default.
• W2759231887 cites W2158252341 @default.
• W2759231887 cites W2169362733 @default.
• W2759231887 cites W2188811924 @default.
• W2759231887 cites W2259709647 @default.
• W2759231887 cites W2263972934 @default.
• W2759231887 cites W2281974748 @default.
• W2759231887 cites W2286299526 @default.
• W2759231887 cites W2294764545 @default.
• W2759231887 cites W2339388181 @default.
• W2759231887 cites W2347089414 @default.
• W2759231887 cites W2413074882 @default.
• W2759231887 cites W2539122817 @default.
• W2759231887 cites W2543603406 @default.
• W2759231887 cites W2563513585 @default.
• W2759231887 cites W2605829102 @default.
• W2759231887 cites W2610916249 @default.
• W2759231887 cites W2612683641 @default.
• W2759231887 cites W2739016310 @default.
• W2759231887 cites W3190336012 @default.
• W2759231887 cites W65678198 @default.
• W2759231887 doi "https://doi.org/10.1016/j.ejphar.2017.09.044" @default.
• W2759231887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28970014" @default.
• W2759231887 hasPublicationYear "2018" @default.
• W2759231887 type Work @default.
• W2759231887 sameAs 2759231887 @default.
• W2759231887 citedByCount "23" @default.
• W2759231887 countsByYear W27592318872018 @default.
• W2759231887 countsByYear W27592318872019 @default.
• W2759231887 countsByYear W27592318872020 @default.
• W2759231887 countsByYear W27592318872021 @default.
• W2759231887 countsByYear W27592318872022 @default.
• W2759231887 countsByYear W27592318872023 @default.
• W2759231887 crossrefType "journal-article" @default.
• W2759231887 hasAuthorship W2759231887A5000139771 @default.
• W2759231887 hasAuthorship W2759231887A5021257221 @default.
• W2759231887 hasAuthorship W2759231887A5054106836 @default.
• W2759231887 hasAuthorship W2759231887A5071941913 @default.
• W2759231887 hasAuthorship W2759231887A5077573350 @default.
• W2759231887 hasAuthorship W2759231887A5085356549 @default.
• W2759231887 hasAuthorship W2759231887A5087329343 @default.
• W2759231887 hasConcept C101666144 @default.
• W2759231887 hasConcept C1122143 @default.
• W2759231887 hasConcept C116484652 @default.
• W2759231887 hasConcept C13373296 @default.
• W2759231887 hasConcept C170493617 @default.
• W2759231887 hasConcept C191732599 @default.
• W2759231887 hasConcept C203014093 @default.
• W2759231887 hasConcept C2776090121 @default.
• W2759231887 hasConcept C2776914184 @default.
• W2759231887 hasConcept C2778690821 @default.

• next